Proadrenomedullin N-terminal 20 peptide: Minimal active region to regulate nicotinic receptors

Hypertension

Volumn 32, Issue 5, 1998, Pages 907-916

  Mahata, Manjula ^a   Mahata, Sushil K ^a   Parmer, Robert J ^a   O'Connor, Daniel T ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Adrenal gland; Adrenomedullin; Catecholamines; Chromaffin granule; Chromogranin

Indexed keywords

CATECHOLAMINE; NICOTINIC RECEPTOR; PROADRENOMEDULLIN;

ANIMAL CELL; ARTICLE; CATECHOLAMINE METABOLISM; CATECHOLAMINE RELEASE; CONTROLLED STUDY; HORMONAL REGULATION; HORMONE ACTION; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SODIUM TRANSPORT;

EID: 0031771025     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.32.5.907     Document Type: Article

References (47)

1. Kitamura K, Sakata J, Kangawa K, Kojima M, Matsuo H, Eto T. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin [published correction appears in Biochem Biophys Res Commun. 1994;202:643]. Biochem Biophys Res Commun. 1993;194: 720-725.
2. Sakata J, Shimokubo T, Kitamura K, Nakamura S, Kangawa K, Matsuo H, Eto T. Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide. Biochem Biophys Res Commun. 1993;195:921-927.
3. Kitamura K, Kangawa K, Kojima M, Ichiki Y, Matsuo H, Eto T. Complete amino acid sequence of porcine adrenomedullin and cloning of cDNA encoding its precursor [published correction appears in FEBS Lett. 1994;348:220]. FEBS Lett. 1994;338:306-310.
4. Washimine H, Kitamura K, Ichiki Y, Yamamoto Y, Kangawa K, Matsuo H, Eto T. Immunoreactive proadrenomedullin N-terminal 20 peptide in human tissue, plasma and urine. Biochem Biophys Res Commun. 1994; 202:1081-1087.
5. Ishizaka Y, Ishizaka Y, Tanaka M, Kitamura K, Kangawa K, Minamino N, Matsuo H, Eto T. Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells. Biochem Biophys Res Commun. 1994; 200:642-646.
6. Kitamura K, Kangawa K, Ishiyama Y, Washimine H, Ichiki Y, Kawamoto M, Minamino N, Matsuo H, Eto T. Identification and hypotensive activity of proadrenomedullin N-terminal 20 peptide (PAMP). FEBS Lett. 1994;351:35-37.
7. Kuwasako K, Kitamura K, Ishiyama Y, Washimine H, Kato J, Kangawa K, Eto T. Purification and characterization of PAMP-12 (PAMP[9-20]) in porcine adrenal medulla as a major endogenous biologically active peptide. FEBS Lett. 1997;414:105-110.
8. Fry RC, Champion HC, Lawrence TC, Murphy WA, Coy DH, Kadowitz PJ. Proadrenomedullin NH2-terminal peptide (PAMP)(12-20) has vasodepressor activity in the rat and cat. Life Sci. 1997;60:L161-L167.
9. Champion HC, Czapla MA, Friedman DE, Lambert DG, Murphy WA, Coy DH, Kadowitz PJ. Tone-dependent vasodilator responses to proadrenomedullin NH2-terminal 20 peptide in the hindquarters vascular bed of the rat. Peptides. 1997;18:513-519.
10. Champion HC, Murphy WA, Coy DH, Kadowitz PJ. Proadrenomedullin NH2-terminal 20 peptide has direct vasodilator activity in the cat. Am J Physiol. 1997;272(pt 2):R1047-R1054.
11. Shimosawa T, Fujita T. Hypotensive effect of a newly identified peptide, proadrenomedullin N-terminal 20 peptide Hypertension. 1996;28: 325-329.
12. Shimosawa T, Ando K, Fujita T. A newly identified peptide, proadrenomedullin N-terminal 20 peptide, induces hypotensive action via pertussis toxin-sensitive mechanisms. Hypertension. 1997;30: 1009-1014.
13. Kohno M, Hanehira T, Kano H, Horio T, Yokokawa K, Ikeda M, Minami M, Yasunari K, Yoshikawa J. Plasma adrenomedullin concentrations in essential hypertension. Hypertension. 1996;27:102-107.
14. Eto T, Washimine H, Kato J, Kitamura K, Yamamoto Y. Adrenomedullin and proadrenomedullin N-terminal 20 peptide in impaired renal function. Kidney Int Suppl. 1996;55:S148-S149.
15. Etoh T, Kato J, Washimine H, Imamura T, Kitamura K, Koiwaya Y, Kangawa K, Eto T. Plasma proadrenomedullin N-terminal 20 peptide (PAMP) in patients with congestive heart failure. Horm Metab Res. 1997;29:46-47.
16. Inatsu H, Sakata J, Shimokubo T, Kitani M, Nishizono M, Washimine H, Kitamura K, Kangawa K, Matsuo H, Eto T. Distribution and characterization of rat immunoreactive proadrenomedullin N-terminal 20 peptide (PAMP) and the augmented cardiac PAMP in spontaneously hypertensive rat. Biochem Mol Biol Int. 1996;38:365-372.
17. Vari RC, Adkins SD, Samson WK. Renal effects of adrenomedullin in the rat. Proc Soc Exp Biol Med. 1996;211:178-183.
18. Feng CJ, Kang B, Kaye AD, Kadowitz PJ, Nossaman BD. L-NAME modulates responses to adrenomedullin in the hindquarters vascular bed of the rat. Life Sci. 1994;55:L433-L438.
19. Nossaman BD, Feng CJ, Kaye AD, DeWitt B, Coy DH, Murphy WA, Kadowitz PJ. Pulmonary vasodilator responses to adrenomedullin are reduced by NOS inhibitors in rats but not in cats. Am J Physiol. 1996; 270(pt 1):L782-L789.
20. Majid DS, Kadowitz PJ, Coy DH, Navar LG. Renal responses to intra-artenal administration of adrenomedullin in dogs. Am J Physiol. 1996; 270(pt 2):F200-F205.
21. Shimosawa T, Ito Y, Ando K, Kitamura K, Kangawa K, Fujita T. Proadrenomedullin NH(2)-terminal 20 peptide, a new product of the adrenomedullin gene, inhibits norepinephrine overflow from nerve endings. J Clin Invest. 1995;96:1672-1676.
22. Champion HC, Erickson CC, Simoneaux ML, Bivalacqua TJ, Murphy WA, Coy DH, Kadowitz PJ. Proadrenomedullin NH2-terminal 20 peptide has cAMP-mediated vasodilator activity in the mesenteric vascular bed of the cat. Peptides. 1996;17:1379-1387.
23. Katoh F, Kitamura K, Niina H, Yamamoto R, Washimine H, Kangawa K, Yamamoto Y, Kobayashi H, Eto T, Wada A. Proadrenomedullin N-terminal 20 peptide (PAMP), an endogenous anticholinergic peptide: its exocytotic secretion and inhibition of catecholamine secretion in adrenal medulla. J Neurochem. 1995;64:459-461.
24. Niina H, Kobayashi H, Kitamura K, Katoh F, Eto T, Wada A. Inhibition of catecholamine synthesis by proadrenomedullin N-terminal 20 peptide in cultured bovine adrenal medullary cells. Eur J Pharmacol. 1995;286:95-97.
25. Nagatomo T, Shibuya I, Kabashima N, Harayama N, Ueta Y, Toyohira Y, Uezono Y, Yanagihara N, Izumi F, Wada A, Yamashita H. Proadrenomedullin N-terminal 20 peptide (PAMP) reduces inward currents and Ca2+ rises induced by nicotine in bovine adrenal medullary cells. Life Sci. 1996;59:1723-1730.
26. Takano K, Yamashita N, Fujita T. Proadrenomedullin NH2-terminal 20 peptide inhibits the voltage-gated Ca2+ channel current through a pertussis toxin-sensitive G protein in rat pheochromocytoma-derived PC 12 cells. J Clin Invest. 1996;98:14-17.
27. Greene LA, Tischler AS. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A. 1976;73:2424-2428.
28. Mahata M, Mahata SK, Parmer RJ, O'Connor DT. Vesicular monoamine transport inhibitors: novel action at calcium channels to prevent catecholamine secretion. Hypertension. 1996;28:414-420.
29. Milligan G. Techniques used in the identification and analysis of function of pertussis toxin-sensitive guanine nucleotide binding proteins. Biochem J. 1988;255:1-13.
30. Merrifield RB. Solid phase peptide synthesis, I: the synthesis of a tetrapeptide. J Am Chem Soc. 1963;85:2149-2154.
31. Amy C, Kirshner N. 22Na+ uptake and catecholamine secretion by primary cultures of adrenal medulla cells. J Neurochem. 1982;39:132-142.
32. Pandol SJ, Schoeffield MS, Fimmel CJ, Muallem S. The agonist-sensitive calcium pool in the pancreatic acinar cell: activation of plasma membrane Ca2+ influx mechanism. J Biol Chem 1987;262:16963-16968.
33. Chou PY, Fasman GD. Empirical predictions of protein conformations. Ann Rev Biochem. 1978;47:251-276.
34. Garnier J, Osguthorpe DJ, Robson B. Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. J Mol Biol. 1978;120:97-120.
35. Eisenberg D, Weiss RM, Terwilliger TC. The Hydrophobic moment plot detects periodicity in protein hydrophobicity. Proc Natl Acad Sci U S A. 1984;81:140-144.
36. Protein Data Bank. Available at: http://www.pdb.bnl.gov. Accessed September 1998.
37. Rost B, Schneider R, Sander C. Protein fold recognition by prediction-based threading. J Mol Biol. 1997;270:471-480.
38. EMBL. Predict-protein web server. Available at: http://www.emblheidelberg.de/predictprotein. Accessed September 1998.
39. Jesior J-C, Filhol A, Tranqui D. Fold-It (light): an interactive program for Macintosh computers to analyze and display Protein Data Bank coordinate files. J Appl Cryst. 1994;27:1075.
40. Kirshner N. Sodium and calcium channels in cultured bovine adrenal medulla cells. In: Rosenheck K, Lelkes PI, eds. Stimulus-Secretion Coupling in Chromaffin Cells. Vol 2. Boca Raton, Fla: CRC Press; 1987:71-86.
41. Inoue K, Nakazawa K, Ohara-Imaizumi M, Obama T, Fujimori K, Takanaka A. Antagonism by reactive blue 2 but not by brilliant blue G of extracellular ATP-evoked responses in PC12 phaeochromocyloma cells. Br J Pharmacol. 1991;102:851-854.
42. Boksa P, Livett BG. Desensitization to nicotinic cholinergic agonists and K+, agents that stimulate catecholamine secretion, in isolated adrenal chromaffin cells. J Neurochem. 1984;42:607-617.
43. Rausch DM, Lewis DL, Barker JL, Eiden LE. Functional expression of dihydropyridine-insensitive calcium channels during PC12 cell differentiation by nerve growth factor (NGF), oncogenic ras, or src tyrosine kinase. Cell Mol Neurobiol. 1990;10:237-255.
44. Mahata SK, O'Connor DT, Mahata M, Yoo SH, Taupenot L, Wu H, Gill BM, Parmer RJ. Novel autocrine feedback control of catecholamine release: a discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist. J Clin Invest. 1997;100:1623-1633.
45. Grant GA. Synthetic Peptides: A User's Guide. New York, NY: WH Freeman and Co; 1992.
46. Champion HC, Fry RC, Murphy WA, Coy DH, Kadowitz PJ. Catecholamine release mediates pressor effects of adrenomedullin-(15-22) in the rat. Hypertension. 1996;28:1041-1046.
47. Watanabe TX, Itahara Y, Inui T, Yoshizawa-Kumagaye K, Nakajima K, Sakakibara S. Vasopressor activities of N-terminal fragments of adrenomedullin in anesthetized rat. Biochem Biophys Res Commun. 1996; 219:59-63.