Fluorescence in situ hybridization for the BCR/ABL rearrangement is dependent on the percentage of nonlymphocytic cells in peripheral blood stem cell harvests

Journal of Hematotherapy and Stem Cell Research

Volumn 7, Issue 5, 1998, Pages 425-430

  Bornhäuser, Martin ^a   Mohr, Brigitte ^a   Ehrenlechner, Ulrike ^a   Neubauer, Andreas ^a   Ehninger, Gerhard ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; CD34 ANTIGEN;

ADULT; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; CELL COMPOSITION; CELL SELECTION; CELL SEPARATION; CELL TRANSPLANTATION; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; LEUKAPHERESIS; MINIMAL RESIDUAL DISEASE; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL;

EID: 0031770680     PISSN: 15258165     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.1.1998.7.425     Document Type: Article

References (14)

1. Carella, A.M., Podesta, M., & Frassoni, F. Collection of "normal" blood repopulating cells during early hematopoietic recovery after intensive conventional chemotherapy in chronic myelogenous leukemia. Bone Marrow Transplant. 12:267, 1993.
2. + cells present in autologous marrow of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow transplantation CML. Blood 83:3068, 1994.
3. Martin-Henao, G.A., Ingles-Esteve, J., Cancelas, J.A., et al. Isolation of CD34+ hematopoietic progenitor cells in chronic myeloid leukemia by magnetic activated cell sorting. Bone Marrow Transplant. 18:603, 1996.
4. Verfaille, C.M., Bhatia, R., Miller, W., et al. BCR/ABL-negative primitive progenitors suitable for transplantation can be selected from the marrow of most early-chronic phase but not accelerated-phase chronic myelogenous leukemia patients. Blood 87:4770, 1996.
5. Lin, F., van Rhee, F., Goldman, J.M., et al. Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation. Blood 87:4473, 1996.
6. Sinclair, P.B., Green, A.R., Grace, C., et al. Improved sensitivity of BCR-ABL detection: A triple-probe three-color fluorescence in situ hybridization system. Blood 90:1395, 1997.
7. Lichter, P., Boyle, A.L., Cremer, T., et al. Analysis of genes and chromosomes by nonisotopic in situ hybridization. Genet. Anal. Tech. Appl. 8:24, 1991.
8. Biernaux, C., Loos, M., Sels, A., et al. Detection of major bcr-abl gene expression at a very low level in blood cells of some healthy individuals. Blood 86:3118, 1995.
9. lo population in chronic myeloid leukemia: An analysis using interphase fluorescence in situ hybridization. Blood 86:737, 1995.
10. Bain, B.J. The role of cytogenetics in the assessment in the assessment of haematological disorders. In Human Cytogenetics: A Practical Approach, eds. Rooney, D.E. & Czepulkowski, B.H. Oxford University Press, New York, 1992, 2:121.
11. Chen, Z., Notohamiprodjo, M., Richards, P.D., et al. Some observations on fluorescence in situ hybridization evaluation of chronic myelocytic leukemia. Cancer Genet. Cytogenet. 98:1, 1997.
12. + cells arising from hematopoietic progenitors in chronic myeloid leukemia. Blood 83:1744, 1994.
13. Leitner, A., Strobl, H., Fischmeister, G., et al. Lack of DANN synthesis among CD34+ cells in cord blood and cytokine mobilized blood. Br. J. Haematol. 92:255, 1996.
14. Wa'el, E.R., Tapani, R., Vettenranta, K., et al. Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukemia: A metaphase-FISH study. Br. J. Haematol. 92:365, 1996.