Analysis of clinical and environmental strains of nontoxigenic Vibrio cholerae for susceptibility to CTXΦ: Molecular basis for origination of new strains with epidemic potential

Infection and Immunity

Volumn 66, Issue 12, 1998, Pages 5819-5825

  Faruque, Shah M ^a,b   Asadulghani, ^a   Saha, Manujendra N ^a   Alim, A R M Abdul ^a   Albert, M John ^a   Islam, K M Nasirul ^a   Mekalanos, John J ^c  

^a INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH   (Bangladesh)

^b ICDDRB Laboratory Sciences Division   (Bangladesh)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOSOME RNA;

ANIMAL TISSUE; ARTICLE; BACTERIAL VIRULENCE; BACTERIOPHAGE; BACTERIUM TRANSFORMATION; CHOLERA; CLONE; DNA RESTRICTION; DNA STRUCTURE; EPIDEMIC; LYSOGENIZATION; MOUSE; NEWBORN; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REGULATOR GENE; VIBRIO CHOLERAE;

VIBRIO CHOLERAE;

EID: 0031769501     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.12.5819-5825.1998     Document Type: Article

References (37)

1. Baselski, V. S., R. A. Medina, and C. D. Parker. 1979. In vivo and in vitro characterization of virulence-deficient mutants of Vibrio cholerae. Infect. Immun. 24:111-116.
2. Baudry, B., A. Fasano, J. Ketley, and J. B. Kaper. 1992. Cloning of a gene (zot) encoding a new toxin produced by Vibrio cholerae. Infect. Immun. 60:428-434.
3. Brosius, J., A. Ullrich, M. A. Raker, A. Gray, T. J. Dull, R. R. Gutell, and H. F. Noller. 1981. Construction and fine mapping of recombinant plasmids containing the rRNB ribosomal RNA operon of E. coli. Plasmid 6:112-118.
4. Dalsgaard, A., H. F. Mortensen, K. Mølbak, F. Dias, O. Serichantalergs, and P. Echeverria. 1996. Molecular characterization of Vibrio cholerae O1 strains isolated during cholera outbreaks in Guinea-Bissau. J. Clin. Microbiol. 34: 1189-1192.
5. Everiss, K. D., K. J. Hughes, M. E. Kovach, and K. M. Peterson. 1994. The Vibrio cholerae acfB colonization determinant encodes an inner membrane protein that is related to a family of signal-transducing proteins. Infect. Immun. 62:3289-3298.
6. Faruque, S. M., S. K. Roy, A. R. M. A. Alim, A. K. Siddique, and M. J. Albert. 1995. Molecular epidemiology of toxigenic Vibrio cholerae in Bangladesh studied by numerical analysis of rRNA gene restriction patterns. J. Clin. Microbiol. 33:2833-2838.
7. Faruque, S. M., K. M. Ahmed, A. R. M. A. Alim, F. Qadri, A. K. Siddique, and M. J. Albert. 1997. Emergence of a new clone of toxigenic Vibrio cholerae O1 biotype E1 Tor displacing V. cholerae O139 Bengal in Bangladesh. J. Clin. Microbiol. 35:624-630.
8. Faruque, S. M., K. M. Ahmed, A. K. Siddique, K. Zaman, A. R. M. A. Alim, and M. J. Albert. 1997. Molecular analysis of toxigenic Vibrio cholerae O139 Bengal strains isolated in Bangladesh between 1993 and 1996: evidence for emergence of a new clone of the Bengal vibrios. J. Clin. Microbiol. 35:2299-2306.
9. Faruque, S. M., L. Comstock, J. B. Kaper, and M. J. Albert. 1994. Distribution of zonula occludens toxin (zot) gene among clinical isolates of Vibrio cholerae O1 from Bangladesh and Africa. J. Diarrhoeal Dis. Res. 12:222-224.
10. Faruque, S. M., Asadulghani, A. R. M. A. Alim, M. J. Albert, K. M. N. Islam, and J. J. Mekalanos. 1998. Induction of the lysogenic phage encoding cholera toxin in naturally occurring strains of toxigenic Vibrio cholerae O1 and O139. Infect. Immun. 66:3752-3757.
11. Feinberg, A., and B. Volgelstein. 1984. A technique for radio labelling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 137:266-267.
12. Ghosh, A. R., H. Koley, D. De, S. Garg, M. K. Bhattacharya, S. K. Bhattacharya, B. Manna, G. B. Nair, T. Shimada, T. Takeda, and Y. Takeda. 1994. Incidence and toxigenicity of Vibrio cholerae in a freshwater lake during the epidemic of cholera caused by serogroup O139 Bengal in Calcutta, India. FEMS Microbiol. Ecol. 14:285-291.
13. Ghosh, C., R. K. Nandi, S. K. Dasgupta, G. B. Nair, R. H. Hall, and A. C. Ghose. 1997. A search for cholera toxin (CT), toxin coregulated pilus (TCP), the regulatory element ToxR and other virulence factors in non-O1/non-O139 Vibrio cholerae. Microb. Pathog. 22:199-208.
14. Goldberg, I., and J. J. Mekalanos. 1986. Effect of a recA mutation on cholera toxin gene amplification and deletion events. J. Bacteriol. 165:723-731.
15. Herrington, D. A., R. H. Hall, G. Losonsky, J. J. Mekalanos, R. K. Taylor, and M. M. Levine. 1988. Toxin, toxin-coregulated pili and ToxR regulon are essential for Vibrio cholerae pathogenesis in humans. J. Exp. Med. 168:1487-1492.
16. Kaper, J. B., J. G. Morris, Jr., and M. Nishibuchi. 1988. DNA probes for pathogenic Vibrio species, p. 65-77. In F. C. Tenover (ed.), DNA probes for infectious disease. CRC Press, Inc., Boca Raton, Fla.
17. Karaolis, D. K., J. A. Johnson, C. C. Bailey, E. C. Boedeker, J. B. Kaper, and P. R. Reeves. 1998. A Vibrio cholerae pathogenicity island associated with epidemic and pandemic strains. Proc. Natl. Acad. Sci. USA 95:3134-3139.
18. Keasler, S. P., and R. H. Hall. 1993. Detection and biotyping Vibrio cholerae O1 with multiplex polymerase chain reaction. Lancet 341:1661.
19. Kovach, M. E., M. D. Shaffer, and K. M. Peterson. 1996. A putative integrase gene defines the distal end of a large cluster of ToxR-regulated colonization genes in Vibrio cholerae. Microbiology 142:2165-2174.
20. Lazar, S., and M. K. Waldor. 1998. ToxR-independent expression of cholera toxin from the replicative form of CTXΦ. Infect. Immun. 66:394-397.
21. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
22. Miller, V. L., and J. J. Mekalanos. 1984. Synthesis of cholera toxin is positively regulated at the transcriptional level by toxR. Proc. Natl. Acad. Sci. USA 81:3471-3475.
23. Miller, V. L., and J. J. Mekalanos. 1988. A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR. J. Bacteriol. 170:2575-2583.
24. Parsot, C., and J. J. Mekalanos. 1991. Expression of the Vibrio cholerae gene encoding aldehyde dehydrogenase is under control of ToxR, the cholera toxin transcriptional activator. J. Bacteriol. 173:2842-2851.
25. Pearson, G. D. N., A. Woods, S. L. Chiang, and J. J. Mekalanos. 1993. CTX genetic element encodes a site-specific recombination system and an intestinal colonization factor. Proc. Natl. Acad. Sci. USA 90:3750-3754.
26. Popovic, T., C. Bopp, Ø. Olsvic, and K. Wachsmuth. 1993. Epidemiological application of a standardized ribotype scheme for Vibrio cholerae O1. J. Clin. Microbiol. 31:2474-2482.
27. Rabbani, G. H., and W. B. Greenough. 1990. Cholera, p. 233-253. In E. Lebenthal and M. Duffy (ed.), Text book of secretory diarrhea. Raven Press, New York, N.Y.
28. Saha, P. K., H. Koley, A. K. Mukhopadhyay, S. K. Bhattacharya, G. B. Nair, B. S. Ramakrishnan, S. Krishnan, T. Takeda, and Y. Takeda. 1996. Non-toxigenic Vibrio cholerae O1 serotype Inaba biotype E1 Tor associated with a cluster of cases of cholera in southern India. J. Clin. Microbiol. 34:1114-1117.
29. Said, B., H. R. Smith, S. M. Scotland, and B. Rowe. 1995. Detection and differentiation of the gene for toxin co-regulated pili (tcpA) in Vibrio cholerae non-O1 using the polymerase chain reaction. FEMS Microbiol. Lett. 125: 205-210.
30. Sharma, C., M. Thungapathra, A. Ghosh, A. K. Mukhopadhyay, A. Basu, R. Mitra, I. Basu, S. K. Bhattacharya, T. Shimada, T. Ramamurthy, T. Takeda, S. Yamasaki, Y. Takeda, and G. B. Nair. 1998. Molecular analysis of non-O1, non-O139 Vibrio cholerae associated with an unusual upsurge in the incidence of cholera-like disease in Calcutta, India. J. Clin. Microbiol. 36:756-763.
31. Southern, E. M. 1975. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:503-517.
32. Stroeher, U. H., K. E. Jedani, B. K. Dredge, R. Morona, M. H. Brown, L. E. Karageorgos, M. J. Albert, and P. A. Manning. 1995. Genetic rearrangements in the rfb regions of Vibrio choleras O1 and O139. Proc. Natl. Acad. Sci. USA 92:10374-10378.
33. Taylor, R., C. Shaw, K. Peterson, P. Spears, and J. Mekalanos. 1988. Safe, live Vibrio cholerae vaccines? Vaccine 6:151-154.
34. Taylor, R. K., V. L. Miller, D. B. Furlong, and J. J. Mekalanos. 1987. Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin. Proc. Natl. Acad. Sci. USA 84:2833-2837.
35. Waldor, M. K., and J. J. Mekalanos. 1996. Lysogenic conversion by a filamentous phage encoding cholera toxin. Science 272:1910-1914.
36. Waldor, M. K., and J. J. Mekalanos. 1994. ToxR regulates virulent gene expression in non-O1 strains of Vibrio cholerae that cause epidemic cholera. Infect. Immun. 62:72-78.
37. World Health Organization. 1974. World Health Organization guidelines for the laboratory diagnosis of cholera. Bacterial Disease Unit, World Health Organization, Geneva, Switzerland.