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Volumn 139, Issue 11, 1998, Pages 4540-4546

Insulin, but not glucose lowering corrects the hyperglucagonemia and increased proglucagon messenger ribonucleic acid levels observed in insulinopenic diabetes

Author keywords

[No Author keywords available]

Indexed keywords

NEUTRAL INSULIN; PROGLUCAGON;

EID: 0031767702     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.11.6294     Document Type: Article
Times cited : (27)

References (31)
  • 1
    • 0026063384 scopus 로고
    • Structure and pancreatic expression of the insulin and glucagon genes
    • Philippe J 1991 Structure and pancreatic expression of the insulin and glucagon genes. Endocr Rev 12:252-271
    • (1991) Endocr Rev , vol.12 , pp. 252-271
    • Philippe, J.1
  • 2
    • 0029035354 scopus 로고
    • Glucagon and its family revisited
    • Lefèbvre PJ 1995 Glucagon and its family revisited. Diabetes Care 18:715-730
    • (1995) Diabetes Care , vol.18 , pp. 715-730
    • Lefèbvre, P.J.1
  • 3
    • 0009446583 scopus 로고    scopus 로고
    • Glucagon and diabetes
    • Lefèbvre PJ (ed) Springer-Verlag, Berlin and Heidelberg
    • Lefèbvre PJ 1996 Glucagon and diabetes. In: Lefèbvre PJ (ed) Handbook of Experimental Pharmacology. Springer-Verlag, Berlin and Heidelberg, vol 3:115-132
    • (1996) Handbook of Experimental Pharmacology , vol.3 , pp. 115-132
    • Lefèbvre, P.J.1
  • 4
    • 0021911168 scopus 로고
    • Correction of hyperglycemia with phloridzin restores the glucagon response to glucose in insulin-deficient dogs: Implications for human diabetes
    • Starke A, Grundy S, McGarry J, Unger RH 1985 Correction of hyperglycemia with phloridzin restores the glucagon response to glucose in insulin-deficient dogs: implications for human diabetes. Proc Natl Acad Sci USA 82:1544-1546
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 1544-1546
    • Starke, A.1    Grundy, S.2    McGarry, J.3    Unger, R.H.4
  • 5
    • 0023155639 scopus 로고
    • Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration
    • Starke A, Imamura T, Unger RH 1987 Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration. J Clin Invest 79:20-24
    • (1987) J Clin Invest , vol.79 , pp. 20-24
    • Starke, A.1    Imamura, T.2    Unger, R.H.3
  • 6
    • 0025933936 scopus 로고
    • Intra-islet insulin permits glucose to directly suppress pancreatic A cell function
    • Greenbaum CJ, Havel PJ, Taborsky Jr J, Klaff LJ 1991 Intra-islet insulin permits glucose to directly suppress pancreatic A cell function. J Clin Invest 88:767-773
    • (1991) J Clin Invest , vol.88 , pp. 767-773
    • Greenbaum, C.J.1    Havel, P.J.2    Taborsky Jr., J.3    Klaff, L.J.4
  • 7
    • 0029937016 scopus 로고    scopus 로고
    • Glucagon response to hypoglycemia is improved by insulin-independent restoration of normoglycemia in diabetic rats
    • Shi ZQ, Rastogi KS, Lekas M, Efendic S, Drucker DJ, Vranic M 1996 Glucagon response to hypoglycemia is improved by insulin-independent restoration of normoglycemia in diabetic rats. Endocrinology 137:3193-3199
    • (1996) Endocrinology , vol.137 , pp. 3193-3199
    • Shi, Z.Q.1    Rastogi, K.S.2    Lekas, M.3    Efendic, S.4    Drucker, D.J.5    Vranic, M.6
  • 8
    • 0024334030 scopus 로고
    • Glucagon gene transcription is negatively regulated by insulin in a hamster islet cell line
    • Philippe J 1989 Glucagon gene transcription is negatively regulated by insulin in a hamster islet cell line. J Clin Invest 84:672-677
    • (1989) J Clin Invest , vol.84 , pp. 672-677
    • Philippe, J.1
  • 9
    • 0025740672 scopus 로고
    • Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element
    • Philippe J 1991 Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element. Proc Natl Acad Sci USA 88:7224-7227
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7224-7227
    • Philippe, J.1
  • 10
    • 0024594508 scopus 로고
    • Molecular and cellular responses of islets during perturbations of glucose homeostasis determined by in situ hybridization histochemistry
    • Chen L, Komiya I, Inman L, McCorkle K, Alam T, Unger RH 1986 Molecular and cellular responses of islets during perturbations of glucose homeostasis determined by in situ hybridization histochemistry. Proc Natl Acad Sci USA 86:1367-1371
    • (1986) Proc Natl Acad Sci USA , vol.86 , pp. 1367-1371
    • Chen, L.1    Komiya, I.2    Inman, L.3    McCorkle, K.4    Alam, T.5    Unger, R.H.6
  • 11
    • 0024393902 scopus 로고
    • Tissue-specific differences in the levels of proglucagon-derived peptides in streptozotocin-induced diabetes
    • Brubaker PL, So DCY, Drucker DJ 1989 Tissue-specific differences in the levels of proglucagon-derived peptides in streptozotocin-induced diabetes. Endocrinology 124:3003-3009
    • (1989) Endocrinology , vol.124 , pp. 3003-3009
    • Brubaker, P.L.1    So, D.C.Y.2    Drucker, D.J.3
  • 12
    • 0025761096 scopus 로고
    • Differential effects of prolonged hyperglycemia on in vivo and in vitro insulin secretion in rats
    • Laury MC, Takao F, Bailbé D, Pénicaud L, Portha B, Picon L, Ktorza A 1991 Differential effects of prolonged hyperglycemia on in vivo and in vitro insulin secretion in rats. Endocrinology 128:2526-2533
    • (1991) Endocrinology , vol.128 , pp. 2526-2533
    • Laury, M.C.1    Takao, F.2    Bailbé, D.3    Pénicaud, L.4    Portha, B.5    Picon, L.6    Ktorza, A.7
  • 13
    • 0019843433 scopus 로고
    • Hyperglycemia induced by glucose infusion in the unrestrained pregnant rat during the last three days of gestation: Metabolic and hormonal changes in the mother and fetuses
    • Ktorza A, Girard J, Kinebanyan MF, Picon L 1981 Hyperglycemia induced by glucose infusion in the unrestrained pregnant rat during the last three days of gestation: metabolic and hormonal changes in the mother and fetuses. Diabetologia 21:569-574
    • (1981) Diabetologia , vol.21 , pp. 569-574
    • Ktorza, A.1    Girard, J.2    Kinebanyan, M.F.3    Picon, L.4
  • 14
    • 0017681502 scopus 로고    scopus 로고
    • The prevention of alloxan-induces diabetes by dimethyl sulfoxide
    • Heikkila RE 1997 The prevention of alloxan-induces diabetes by dimethyl sulfoxide. Eur J Pharmacol 44:191-193
    • (1997) Eur J Pharmacol , vol.44 , pp. 191-193
    • Heikkila, R.E.1
  • 15
  • 18
    • 0021719480 scopus 로고
    • Preproglucagon mRNA: Nucleotide and encoded amino acid sequences of the rat pancreatic cDNA
    • Heinrich G, Gros P, Lund PK, Bentley RC, Habener JF 1984 Preproglucagon mRNA: nucleotide and encoded amino acid sequences of the rat pancreatic cDNA. Endocrinology 115:2176-2181
    • (1984) Endocrinology , vol.115 , pp. 2176-2181
    • Heinrich, G.1    Gros, P.2    Lund, P.K.3    Bentley, R.C.4    Habener, J.F.5
  • 19
    • 0028834891 scopus 로고
    • In vivo effects of glucose and insulin on secretion and gene expression of glucagon in rats
    • Magnan C, Philippe J, Pénicaud L, Ktorza A 1995 In vivo effects of glucose and insulin on secretion and gene expression of glucagon in rats. Endocrinology 136:5370-5376
    • (1995) Endocrinology , vol.136 , pp. 5370-5376
    • Magnan, C.1    Philippe, J.2    Pénicaud, L.3    Ktorza, A.4
  • 20
    • 0345623046 scopus 로고
    • Pancreatic expression of the insulin and glucagon genes: Update 1994
    • Philippe J 1994 Pancreatic expression of the insulin and glucagon genes: update 1994. Endocr Rev 2:21-27
    • (1994) Endocr Rev , vol.2 , pp. 21-27
    • Philippe, J.1
  • 21
    • 0030017340 scopus 로고    scopus 로고
    • Intra-islet cell-cell interactions and insulin secretion
    • Samols E, Stagner JI 1996 Intra-islet cell-cell interactions and insulin secretion. Diabetes Rev 4:207-223
    • (1996) Diabetes Rev , vol.4 , pp. 207-223
    • Samols, E.1    Stagner, J.I.2
  • 22
    • 0028871133 scopus 로고
    • Excessive glucose production, rather than insulin resistance, accounts for hyperglycemia in recent onset streptozotocin-diabetic rats
    • Burcelin R, Eddouks M, Maury J, Kande J, Assan R, Girard J 1995 Excessive glucose production, rather than insulin resistance, accounts for hyperglycemia in recent onset streptozotocin-diabetic rats. Diabetologia 38:283-290
    • (1995) Diabetologia , vol.38 , pp. 283-290
    • Burcelin, R.1    Eddouks, M.2    Maury, J.3    Kande, J.4    Assan, R.5    Girard, J.6
  • 23
    • 0014606996 scopus 로고
    • Diabetogenic action of streptozotocin: Relationship of dose to metabolic response
    • Junod A, Lambert AE, Stauffacher W, Renold AE 1969 Diabetogenic action of streptozotocin: relationship of dose to metabolic response. J Clin Invest 48:2129-2139
    • (1969) J Clin Invest , vol.48 , pp. 2129-2139
    • Junod, A.1    Lambert, A.E.2    Stauffacher, W.3    Renold, A.E.4
  • 24
    • 0015691086 scopus 로고
    • Glucagon release from isolated pancreas in streptozotocin-treated rats
    • Buchanan KD, Mawhinney AA 1973 Glucagon release from isolated pancreas in streptozotocin-treated rats. Diabetes 22:797-800
    • (1973) Diabetes , vol.22 , pp. 797-800
    • Buchanan, K.D.1    Mawhinney, A.A.2
  • 26
    • 0016197888 scopus 로고
    • Glucagon secretion from the perfused rat pancreas
    • Weir GC, Knowlton SD, Martin DB 1974 Glucagon secretion from the perfused rat pancreas. J Clin Invest 54:1403-1412
    • (1974) J Clin Invest , vol.54 , pp. 1403-1412
    • Weir, G.C.1    Knowlton, S.D.2    Martin, D.B.3
  • 27
    • 0023155639 scopus 로고
    • Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration
    • Starke A, Imamura T, Unger RH 1987 Relationship of glucagon suppression by insulin and somatostatin to the ambient glucose concentration. J Clin Invest 79:20-24
    • (1987) J Clin Invest , vol.79 , pp. 20-24
    • Starke, A.1    Imamura, T.2    Unger, R.H.3
  • 29
    • 0022615024 scopus 로고
    • Selective impairtment of pancreatic A cell suppression by glucose during acute alloxan-induced insulinopenia: In vitro study on isolated prefused rat pancreas
    • Flipponi P, Gregorio F, Cristallini S, Ferrandina C, Nicoletti I, Santensanio F 1986 Selective impairtment of pancreatic A cell suppression by glucose during acute alloxan-induced insulinopenia: in vitro study on isolated prefused rat pancreas. Endocrinology 119:408-415
    • (1986) Endocrinology , vol.119 , pp. 408-415
    • Flipponi, P.1    Gregorio, F.2    Cristallini, S.3    Ferrandina, C.4    Nicoletti, I.5    Santensanio, F.6
  • 30
    • 0021153927 scopus 로고
    • Hypoglycemic counter-regulation in normal and diabetic man
    • Gelfand RA, de Fronzo RA 1984 Hypoglycemic counter-regulation in normal and diabetic man. Ann Clin Res 16:84-93
    • (1984) Ann Clin Res , vol.16 , pp. 84-93
    • Gelfand, R.A.1    De Fronzo, R.A.2
  • 31
    • 0028607457 scopus 로고
    • Hypoglycemia: The limiting factor in the management of IDDM
    • Cryer PE 1994 Hypoglycemia: the limiting factor in the management of IDDM. Diabetes 43:1378-1389
    • (1994) Diabetes , vol.43 , pp. 1378-1389
    • Cryer, P.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.