The prevention of alloxan-induced diabetes in mice by dimethyl sulfoxide

European Journal of Pharmacology

Volumn 44, Issue 2, 1977, Pages 191-193

  Heikkila, Richard E ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Alloxan induced diabetes; Dimethyl sulfoxide; DMSO; Hydroxyl radical

Indexed keywords

ALLOXAN; DIMETHYL SULFOXIDE; HYDROXYL RADICAL;

ALLOXAN DIABETES MELLITUS; DIABETES MELLITUS; MOUSE; PREVENTION; THEORETICAL STUDY;

ANIMAL; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIMETHYL SULFOXIDE; MALE; MICE; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0017681502     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(77)90106-6     Document Type: Article

References (10)

1. Current concepts concerning radioprotective and cryoprotective properties of dimethyl sulfoxide in cellular systems
2. The alloxan-dialuric acid cycle and the generation of hydrogen peroxide
3. The catalytic decomposition of hydrogen peroxide by iron salts
4. Specific uptake of labelled alloxan in the pancreatic islets
5. Prevention of alloxan-induced diabetes by ethanol administration
6. Alloxan-induced diabetes: evidence for hydroxyl radical as a cytotoxic intermediate
7. Role of hydroxyl radical scavengers dimethyl sulfoxide, alcohols and methional in the inhibition of prostaglandin biosynthesis
8. Drugs producing diabetes through damage of the insulin secreting cells
9. Toxicity of dimethyl sulfoxide alone and in combination