Molecular simulation of the primary and secondary structures of the Aβ(1-42)peptide of Alzheimer's disease

Medicinal Research Reviews

Volumn 18, Issue 6, 1998, Pages 403-430

  Mager, Peter P ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

helix; sheet; A peptides; Aggregation of peptides; Amyloid; Circular dichroism; Cluster analysis; Conformational transitions; Conformational dependent biological activity; Drug design; Hydrophobic cores of sheets; Medicinal chemistry; Molecular modeling; Molecular simulation; Morbus Alzheimer; Neural networks; Principal component analysis

Indexed keywords

AMYLOID BETA PROTEIN;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ARTICLE; CIRCULAR DICHROISM; COMPUTER SIMULATION; HUMAN; HYDROPHILICITY; HYDROPHOBICITY; MOLECULAR MODEL; PEPTIDE ANALYSIS; PEPTIDE MAPPING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, PEPTIDE;

EID: 0031766850     PISSN: 01986325     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1128(199811)18:6<403::AID-MED4>3.0.CO;2-C     Document Type: Article

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