The MCM16 gene of the yeast Saccharomyces cerevisiae is required for chromosome segregation

Molecular and General Genetics

Volumn 260, Issue 2-3, 1998, Pages 242-250

  Sanyal, K ^a   Ghosh, S K ^a   Sinha, P ^a  

^a BOSE INSTITUTE   (India)

Author keywords

Chromosome segregation; Kinetochore; mcm; Yeast; YPR046W

Indexed keywords

ANTIMITOTIC AGENT; BENOMYL; BETA GALACTOSIDASE; TIABENDAZOLE;

AMINO ACID COMPOSITION; ARTICLE; CELL MUTANT; CENTROMERE; CHROMOSOME 16; CHROMOSOME 3; CHROMOSOME LOSS; CHROMOSOME SEGREGATION; CLONOGENESIS; CONTROLLED STUDY; DRUG SENSITIVITY; FUNGAL GENETICS; GENE DELETION; GENETIC RECOMBINATION; MICROTUBULE; MINICHROMOSOME; NONHUMAN; PRIORITY JOURNAL; RECOMBINANT PLASMID; REPORTER GENE; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION;

BETA-GALACTOSIDASE; CHROMOSOME DELETION; CHROMOSOME SEGREGATION; CLONING, MOLECULAR; FUNGAL PROTEINS; KINETOCHORES; MICROTUBULES; MUTATION; PHENOTYPE; PLASMIDS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION, GENETIC;

SACCHAROMYCES CEREVISIAE;

EID: 0031764366     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050892     Document Type: Article

References (34)

1. Berlin V, Styles CA, Fink GR (1990) BIK1, a protein required for microtubule function during mating and mitosis in Saccharomyces cerevisiae, colocalizes with tubulin. J Cell Biol 111:2573-2586
2. Broach JR, Strathern JN, Hicks JB (1979) Transformation in yeast:development of a hybrid cloning vector and isolation of the CAN1 gene. Gene 8:121-133
3. Chen D-C, Yang B-C, Kuo T-T (1992) One-step transformation of yeast in stationary phase. Curr Genet 21:83-84
4. Cusack S, Hartlein M, Lebermari R (1991) Sequence, structural and evolutionary relationships between class 2 aminoacyl-tRNA synthetases. Nucl Acids Res 19:3489-3498
5. Doheny KF, Sorger PK, Hyman AA, Tugendreich S, Spencer F, Hieter P (1993) Identification of essential components of the Saccharomyces cerevisiae kinetochore. Cell 73:761-774
6. Gerring SL, Spencer F, Hieter P (1990) The CHL1(CTF1) gene product of Saccharomyces cerevisiae is important for chromosome transmission and normal cell cycle progression in G2/M. EMBO J 9:4347-4358
7. Gietz RD, Sugino A (1988) New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74:527-534
8. Hegemann JH, Shero JH, Cottarel G, Philippsen P, Hieter P (1988) Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae. Mol Cell Biol 8:2523-2535.
9. Hartwell LH, Smith D (1985) Altered fidelity of mitotic chromosome transmission in cell-cycle mutants of S. cerevisiae. Genetics 110:381-395
10. Hoyt MA, Geiser JR (1996) Genetic analysis of the mitotic spindle. Annu Rev Genet 30:7-33
11. Hyman AA, Sorger PK (1995) Structure and function of kinetochores in budding yeast. Annu Rev Cell Dev Biol 11:471-495
12. Ito H, Fukuda Y, Murata K, Kimura A (1983) Transformation of intact yeast cells treated with alkali cations. J Bacteriol 153:163-168
13. Koshland D, Rutledge L, Fitzgerald-Hayes M, Hartwell LH (1987) A genetic analysis of dicentric minichromosomes in Saccharomyces cerevisiae. Cell 48:801-812
14. Kouprina N, Kirillov A, Kroll E, Koryabin M, Shestopalov B, Bannikov V, Zakharyev V, Larionov V (1993) Identification and cloning of CHL4 gene controlling chromosome segregation in yeast. Genetics 135:327-341
15. Kroll ES, Hyland KM, Hieter P, Li JJ (1996) Establishing genetic-interaction by a synthetic dosage lethality phenotype. Genetics 143:95-102
16. Lechner J, Ortiz J (1996) The Saccharomyces cerevisiae kinetochore. FEBS Lett 389:70-74
17. Lundblud V (1995) Cloning yeast genes by complementation. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (Third ed.) Short Protocols in Molecular Biology, John Wiley and Sons Inc. New York, London, pp 13-37 13-38.
18. Li R, Murray AW (1991) Feedback control of mitosis in budding yeast. Cell 66:519-531
19. Maine GT, Sinha P, Tye B-K (1984a) Mutants of S. cerevisiae defective in maintenance of minichromosomes. Genetics 106:365-385
20. Maine GT, Surosky RT, Tye B-K (1984b) Isolation and characterization of centromere from chromosome V (CEN5) of S. cerevisiae. Mol Cell Biol 4:86-91
21. Maiti AK, Sinha P (1992) The mcm2 mutation of yeast affects replication, rather than segregation or amplification of the 2-micron plasmid. J Mol Biol 224:545-558
22. Mann C, Davis RW (1983) Instability of dicentric plasmids in yeast. Proc Natl Acad Sci USA 80:228-232
23. McGrew J, Diehl B, Fitzgerald-Haves M (1986) Single base-pair mutations in centromere element III cause aberrant chromosome segregation in Saccharomyces cerevisiae. Mol Cell Biol 6:530-538
24. Merchant AM, Kawasaki Y, Chen Y, Lei M, Tye B-K (1997) A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae. Mol Cell Biol 17:3261-3271
25. Page BD, Snyder M (1993) Chromosome segregation in yeast. Annu Rev Microbiol 47:231-261
26. Reynolds A, Lundblad V. (1995) Yeast vectors and expression assays. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (Third ed.) Short protocols in Molecular Biology, John Wiley and Sons Inc. New York, London, pp 13-29-13-30.
27. Rose MD, Novick P, Thomas JH, Botstein D, Fink GR (1987) A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene 60:237-243
28. Roy N, Poddar A, Lohia A, Sinha P (1997) The mem17 mutation of yeast shows a size-dependent segregational defect of a mini-chromosome. Curr Genet 32:182-189
29. Sherman F, Fink GR, Hicks JB (1986) Methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
30. Sikorski RS, Hieter P (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27
31. Sinha P, Chang V, Tye B-K (1986) A mutant that affects the function of autonomously replicating sequences in yeast. J Mol Biol 192:805-814
32. Stearns T, Hoyt MA, Botstein D (1990) Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function. Genetics 124:251-262
33. Strunnikov AV, Kingsbury J, Koshland D (1995) CEP: Encodes a centromere protein of Saccharomyces cerevisiae. J Cell Biol 128:249-260
34. Tye B-K (1994) The MCM2 3-5 proteins: are they replication-licensing factors? Trends Cell Biol 4:160-166