Intense sympathetic nerve activity in adults with hypopituitarism and untreated growth hormone deficiency

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 6, 1998, Pages 1881-1885

  Sverrisdóttir, Yrsa Bergmann ^a   Elam, Mikael ^a   Herlitz, Hans ^a   Bengtsson, Bengt Åke ^a   Johannsson, Gudmundur ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BROMOCRIPTINE; CORTISONE; DESMOPRESSIN; GLUCOSE; GROWTH HORMONE; SEX HORMONE; SOMATOMEDIN C; THYROTROPIN; THYROXINE;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; FEMALE; GROWTH HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; HYPERTENSION; HYPOPITUITARISM; MALE; ORAL DRUG ADMINISTRATION; ORAL GLUCOSE TOLERANCE TEST; PERONEUS NERVE; PRIORITY JOURNAL; SYMPATHETIC NERVE; SYMPATHETIC TONE;

ADULT; BLOOD GLUCOSE; BODY CONSTITUTION; BODY MASS INDEX; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; GLUCOSE TOLERANCE TEST; HUMAN GROWTH HORMONE; HUMANS; HYPOPITUITARISM; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MALE; MICROELECTRODES; MUSCLES; PERONEAL NERVE; SYMPATHETIC NERVOUS SYSTEM; THYROTROPIN; TUNGSTEN;

EID: 0031763098     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.6.1881     Document Type: Article

References (49)

1. Rosén T, Edén S, Larson G, Wilhelmsen L, Bengtsson BA. 1993 Cardiovascular risk factors in adult patients with growth hormone deficiency. Acta Endocrinol (Copenh). 129:195-200.
2. Rosén T, Bengtsson B-Å. 1990 Premature mortality due to cardiovascular diseases in hypopituitarism. Lancet. 336:285-288.
3. Bengtsson B-Å, Rosén T, Johansson JO, Johannsson G, Oscarsson J, Landin-Wilhelmsen K. 1995 Cardiovascular risk factors in adults with growth hormone deficiency. Endocrinol Metab. 2(Suppl):29-35.
4. Johansson J-O, Fowelin J, Landin K, Lager I, Bengtsson B-Å. 1995 Growth hormone-deficient adults are insulin-resistant. Metabolism. 44:1126-1129.
5. Spraul M, Ravussin E, Fontvieille AM, Rising R, Larson E, Anderson EA. 1993 Reduced sympathetic nervous activity. A potential predisposing to body weight gain. J Clin Invest. 92:1730-1735.
6. Rowe JW, Young JB, Minaker KL, Stevens AL, Pallotta J, Landsberg L. 1981 Effect of insulin and glucose infusion on sympathetic nervous system activity in normal man. Diabetes. 30:219-225.
7. Kurosawa M, Sato A, Swenson RS, Takahashi Y. 1986 Sympatho-adrenal medullary functions in response to intracerebroventricularly injected corticotropin-releasing factor in anesthetized rats. Brain Res. 367:250-257.
8. Tsunoda S, Shiozawa Z, Mano T. 1988 Microncurographic analysis of thyrotropin-releasing hormone effects on sympathetic outflow in human muscle nerves. J Auton Nerv Syst. 23:207-211.
9. Jörgensen JOL, Pedersen SA, Thuesen L, et al. 1989 Beneficial effects of growth hormone treatment in GH-deficient adults. Lancet. 1:1221-1225.
10. Lehmann ED, Gosling RG. 1991 Measurement aortic distensibility. Lancet. 338:1075.
11. Gudbjornsdottir S, Lönnroth P, Sverrisdottir YB, Wallin BG, Elam M. 1996 Sympathetic nerve activity and insulin in obese normotensive and hypertensive men. Hypertension. 27:276-280.
12. Yamada Y, Miyajima E, Tochikubo O, Matsukawa T, Ishii M. 1989 Age-related changes in muscle sympathetic nerve activity in essential hypertension. Hypertension. 13:870-877.
13. Floras JS, Hara K. 1993 Sympathoneural and haemodynamic characteristics of young subjects with mild essential hypertension. J Hypertens. 11:647-655.
14. Schobel HP, Ringkamp M, Behrmann A, Forster C, Schmieder RE, Handwerker HO. 1996 Hemodynamic and sympathetic nerve responses to painful stimuli in normotensive and borderline hypertensive subjects. Pain. 66:117-124.
15. Somers VK, Mark AL. 1992 Sympathetic neural mechanisms in hypertension. In: Bannister R, Mathias CJ, eds. Autonomic failure: a textbook of clinical disorders of the autonomic nervous system, 3rd ed. New York: Oxford University Press; 804-821.
16. Cohn JN, Levine TB, Metha J. 1984 Plasma norepinephrine as a guide to prognosis in patients with congestive heart failure. N Engl J Med. 311:819-823.
17. Kaye DM, Lambert GW, Dewar EM, Jennings GL, Esler M. 1994 Neurochemical evidence of cardiac sympathetic activation and increased central nervous system norepinephrine turnover in severe congestive heart failure. J Am Coll Cardiol. 23:570-578.
18. Bülow B, Hagmar L, Mikozy Z, Nordström C-H, Erfurth EM. 1996 Increased cerebrovascular mortality in patients with hypopituitarism. Clin Endocrinol Metab. 46:75-81.
19. Segal KR, Burastero S, Chun A, Coronel P, Pierson RN, Wang J. 1991 Estimation of extracellular and total body water by multiple-frequency bioelectrical-impedance measurement. Am J Clin Nutr. 54:26-29.
20. Wallin BG, Sundlöv G, Eriksson B-M, Dominiak P, Grobecker H, Lindblad LE. 1981 Plasma noradrenaline correlates to sympathetic muscle nerve activity in normotensive man. Acta Physiol Scand. 111:69-73.
21. Wallin BG, Esler M, Donvard P, Eisenhofer G, Ferrier C, Westerrnan R, et al. 1992 Simultaneous measurements of cardiac noradrenaline spillover and sympathetic outflow to skeletal muscle in humans. J Physiol. 453:45-58.
22. Wallin BG, Thompson JM, Jennings GL, Esler MD. 1996 Renal noradrenaline spillover correlates with muscle sympathetic nerve activity in humans. J Physiol. 491.3:881-887.
23. Vallbo ÅB, Hagbarth KE, Torebjörk HE, Wallin BG. 1979 Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves. Physiol Rev. 59:919-957.
24. Wallin BG, Elam M. 1997 Microneurography and autonomic dysfunction. In: Low PA, ed. Clinical autonomie disorders, 2nd ed. Philadelphia: Lippincott-Raven; 233-243.
25. Ng AV, Callister R, Johnson DG, Seals DR. 1993 Age and gender influence muscle sympathetic nerve activity at rest in healthy humans. Hypertension, 21:498-503.
26. Ho KY, Evans WS, Blizzard RM, Veldhuis JD, Merriam GR, Samojlik E, et al. 1987 Effects of sex and age on 24-hour profile of growth hormone secretion in man: importance of endogenous estradiol concentrations. J Clin Endocrinol Metab. 64:51-58.
27. Sundlöf G, Wallin BG. 1978 Human muscle nerve sympathetic activity at rest. Relationship to blood pressure and age. J Physiol (Lond). 274:621-637.
28. Flinkenstein JW, Roffwarg HP, Boyar RM, Kream J, Hellman L. 1972 Age-related change in the twenty-four-hour spontaneous secretion of growth hormone. J Clin Endocrinol Metab. 35:665-670.
29. Homyak M, Cejnar M, Elam M, Matousek M, Wallin BG. 1991 Sympathetic muscle nerve activity during sleep in man. Brain. 114:2181-2195.
30. Takahashi Y, Kipnis DM, Daughaday WH. 1968 Growth hormone secretion during sleep. J Clin Invest. 47:2079-2090.
31. Andersson B, Elam M, Wallin BG, Björntorp P, Andersson OK. 1991 Effect of energy-restricted diet on sympathetic muscle nerve activity in obese women. Hypertension. 18:783-789.
32. Iranmanesh A, Lizarralde G, Veldhuis JD. 1991 Age and relative adiposity are specific negative determinant of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men. J Clin Endocrinol Metab. 73:1081-1088.
33. Williams T, Maxon H, Thomer MO, Frohman LA. 1985 Blunted growth hormone (GH) response to GH-releasing hormone in hypothyroidism resolves in the euthyroid state. J Clin Endocrinol Metab. 61:454-456.
34. Matsukawa T, Mano T, Gotoh E, Minamisawa K, Ishii M. 1993 Altered muscle sympathetic nerve activity in hyperthyroidism and hypothyroididsm. J Auton Nerv Syst. 42:171-176.
35. Iranmanesh A, Lizarralde G, Johnson ML, Veldhuis JD. 1991 Nature of altered growth hormone secretion in hyperthyroidism. J Clin Endocrinol Metab. 72:108-115.
36. Reaven GM. 1995 Pathophysiology of insulin resistance in human disease. Physiol Rev. 75:473-486.
37. Rosén T, Bosaeus I, Tölli J, Lindstedt G, Bengtsson BÅ. 1993 Increased body fat and decreased extracellular fluid volume in adults with growth hormone deficiency. Clin Endocrinol (Oxf). 38:63-71.
38. Hartman ML, Clayton PE, Johnson ML, et al. 1993 A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans. J Clin Invest. 91:2453-2462.
39. de Gennaro CV, Cattaneo E, Cocchi D, Muller EE, Maggi A. 1988 Growth hormone regulation of growth hormone-releasing hormone gene expression. Peptides. 9:985-988.
40. Rogers KV, Vivian L, Steiner RA, Clifton DK. 1988 The effect of hypophysectomy and growth hormone administration on pre-prosomatosatin messenger ribonucleic acid in the periventricular nucleus of the rat hypothalamus. Endocrinology. 122:586-591.
41. Durand D, Martin JB, Brazeau P. 1978 Evidence for a role of α-adrenergic mechanism in regulation of episodic growth secretion in the rat. Endocrinology. 100:722-728.
42. Lambert GW, Thompson JM, Turner AG, et al. 1997 Cerebral noradrenaline spillover and its relation to muscle sympathetic nervous activity in healthy human subjects. J Auton Nerv Syst. 64:57-64.
43. Scherrer U, Vollenweider P, Randin D, Jéquier E, Nicod P, Tappz L. 1993 Suppression of insulin-induced sympathetic activation and vasodilation by dexamethasone in humans. Circulation. 88:388-394.
44. Randin D, Vollenweider P, Tappy L, Jéquier E, Nigod P, Scherrer U. 1995 Suppression of alcohol-induced hypertension by dexamethasone. N Engl J Med. 332:1733-1737.
45. Miyajima E, Yamada Y, Yoshida Y, et al. 1991 Muscle sympathetic nerve activity in renovascular hypertension and primary aldosteronism. Hypertension. 17:1057-1062.
46. Converse RL, Jacobsen TN, Toto RD, et al. 1992 Sympathetic overactivity in patients with chronic renal failure. N Engl J Med. 327:1912-1918.
47. Böger H, Skamira C, Bode-Böger SM, Brabant G, von zur Mühlen A, Frölich JC. 1996 Nitric oxide may mediate the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency J Clin Invest. 98:2706-2713.
48. Elam M, Casale R, La Rovere MT, Mortara A, Tavazzi L. 1993 Is sympathetic neural hyperactivity in chronic heart failure affected by heart transplantation? Eur Heart J. 14:521-525.
49. Rundquist B, Casale R, Sverrisdottir YB, Friberg P, Mortara A, Elam M. 1997 Rapid fall in sympathetic nerve hyperactivity in patients with heart failure after cardiac transplantation. J Cardiac Failure. 3:1-6.