Hemodynamic and sympathetic nerve responses to painful stimuli in normotensive and borderline hypertensive subjects

Pain

Volumn 66, Issue 2-3, 1996, Pages 117-124

  Schobel, Hans P ^a,b   Ringkamp, Matthias ^a   Behrmann, Annja ^a   Forster, Clemens ^a   Schmieder, Roland E ^a   Handwerker, Hermann O ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b Med Klin IV Endokrinol N   (Germany)

Author keywords

Baroreflex; Blood pressure; Borderline hypertension; Normotension; Pain; Sympathetic activity

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HEMODYNAMICS; HUMAN; HYPERTENSION; PAIN; PAIN THRESHOLD; PRESSORECEPTOR; PRIORITY JOURNAL; SYMPATHETIC FUNCTION;

EID: 0030220689     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3959(96)03079-5     Document Type: Article

References (27)

1. Berne C., Fagius J., Niklasson F. Sympathetic response to oral carbohydrate administration. Evidence from microelectrode nerve recordings. J. Clin. Invest. 84:1989;1403-1409.
2. Bruehl S., Carlson C.R., McCubbin J.A. The relationship between blood pressure and pain sensitivity in normotensives. Pain. 48:1992;463-467.
3. DeJong W., Petty M.A., Sitsen J.M.A. Role of opioid peptides in brain mechanisms regulating blood pressure. Chest. 83(Suppl. 2):1983;306-308.
4. Delius W., Hagbarth K.E., Hongell A., Wallin B.G. General characteristics of sympathetic activity in human muscle nerves. Acta Physiol. Scand. 84:1972;65-81.
5. France C., Ditto B., Adler P. Pain sensitivity in offspring of hypertensives at rest and during baroreflex stimulation. J. Behav. Med. 14:1991;513-525.
6. Ghione S., Rosa C., Mezzasalma L., Panattoni E. Arterial hypertension is associated with hypalgesia in humans. Hypertension. 12:1988;492-497.
7. Guasti, L., Merlo, B., Cattaneo, R., Verga, R., Gaudio, G., Bianchi, L., Bertolini A, Grandi, A.M. and Venco, A., Hypertension-related hypalgesia: normalization of pain sensitivity during anti-hypertensive treatment, Am. J. Hypertens., 8 (4) (1995) 65A [abstract].
8. Koltzenburg M., Handwerker H.O. Differential ability of human cutaneous nociceptors to signal mechanical pain and to produce vasodilation. J. Neurosci. 14:1994;1756-1765.
9. Magerl W., Geldner G., Handwerker H.O. Pain and vascular reflexes in man elicited by prolonged noxious mechano-stimulation. Pain. 43:1990;219-225.
10. Maixner W., Touw K.B., Brody M.J., Gebhart G.F., Long J.P. Factors influencing the altered pain perception in the spontaneously hypertensive rat. Brain Res. 237:1982;137-145.
11. Maixner W., Randich A. Role of the right vagal nerve trunk in antinociception. Brain Res. 298:1984;374-377.
12. Mark A.L., Victor R.G., Nerhed C., Wallin B.G. Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercises in humans. Circ. Res. 57:1985;461-469.
13. McCubbin J.A., Bruehl S. Do endogenous opioids mediate the relationship between blood pressure and pain sensitivity in normotensives? Pain. 57:1994;63-67.
14. Parati G., Casadei R., Groppelli A.C., Di Rienzo M., Mancia G. Comparison of finger and intra-arterial blood pressure monitoring at rest and during laboratory testing. Hypertension. 13:1989;647-655.
15. Randich A., Maixner W. Interactions between cardiovascular and pain regulatory systems. Neurosci. Biobehav. Rev. 8:1984;343-367.
16. Randich A., Maixner W. [D-Ala2]-Methionine enkephalinamide reflexively induces antinociception by activating vagal afferents. Pharmacol. Biochem. Behav. 21:1984;441-448.
17. Randich A., Maixner W. The role of sinoaortic and cardiopulmonary baroreceptor reflex arcs in nociception and stress-induced analgesia. Ann. NY Acad. Sci. 467:1986;385-401.
18. Randich A., Thurston C.L., Ludwig P.S., Timmerman M.R., Gebhart G.F. Antinociception and cardiovascular responses produced by intravenous morphine: the role of vagal afferents. Brain Res. 543:1991;256-270.
19. Saavedra J.M. Naloxone reversible decrease in pain sensitivity in young adult spontaneously hypertensive rats. Brain Res. 209:1981;245-249.
20. Sheps D.S., Bragdon E.E., Gray I.I.I.T.F., Ballenger M., Usedom J.E., Maixner W. Relation between systemic hypertension and pain perception. Am. J. Cardiol. 70:1992;3F-5F.
21. Sitsen J.M.A., de Jong W. Hypoalgesia in genetically hypertensive rats (SHR) is absent in rats with experimental hypertension. Hypertension. 5:1983;185-190.
22. Schobel H.P., Oren R.M., Mark A.L., Ferguson D.W. Naloxone potentiates cardiopulmonary baroreflex sympathetic control in normal humans. Circ. Res. 70:1992;172-183.
23. Schobel H.P., Schmieder R.E., Hartmann S., SchSchinger H., Luft F.C. Effects of Bromocriptine on Cardiovascular Regulation in Healthy Humans. Hypertension. 25:1995;1075-1082.
24. Vallbo A.B., Hagbarth K-E, Torebjork H.E., Wallin B.G. Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves. Physiol. Rev. 59:1979;919-957.
25. Wallin, G., Intraneural recording and autonomic function in man. In: R. Bannister (Ed.), Autonomic Failure. London, Oxford University Press, 1983, pp. 36-51.
26. Zamir N., Simantow R., Segal M. Pain sensitivity and opiod activity in genetically and experimentally hypertensive rats. Brain Res. 184:1980;299-310.
27. Zamir N., Shuber E. Altered pain perception in hypertensive humans. Brain Res. 201:1980;471-474.