Adrenocortical overexpression of gastric inhibitory polypeptide receptor underlies food-dependent Cushing's syndrome

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 8, 1998, Pages 2781-2785

  N'Diaye, Nina ^a   Tremblay, Johanne ^a   Hamet, Pavel ^a   De Herder, Wouter W ^b   Lacroix, André ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIC INHIBITORY POLYPEPTIDE; HORMONE RECEPTOR;

ADRENAL CORTEX ADENOMA; ADRENAL HYPERPLASIA; ARTICLE; CUSHING DISEASE; GENE SEQUENCE; HUMAN; HUMAN TISSUE; HYDROCORTISONE RELEASE; PRIORITY JOURNAL; RNA HYBRIDIZATION; STEROIDOGENESIS;

ADRENAL CORTEX; ADULT; ALTERNATIVE SPLICING; BASE SEQUENCE; CUSHING SYNDROME; DNA, COMPLEMENTARY; FEMALE; FOOD; GASTRIC INHIBITORY POLYPEPTIDE; GENE EXPRESSION; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; PANCREAS; POLYMERASE CHAIN REACTION; RECEPTORS, GASTROINTESTINAL HORMONE; RNA-DIRECTED DNA POLYMERASE;

EID: 0031757835     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.8.2781     Document Type: Article

References (27)

1. Nieman L, Cutler Jr GB. 1995 Cushing's syndrome. In: De Groot LJ, eds. Endocrinology. Philadelphia: Saunders; 1741-1770.
2. Lieberman SA, Eccleshall TR, Feldman D. 1994 ACTH-independent massive bilateral adrenal disease (AIMBAD): a subtype of Cushing's syndrome with major diagnostic and therapeutic implications. Eur J Clin Endocrinol. 131:67-73.
3. Stratakis CA, Carney JA, Lin J-P, et al. 1996 Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2. J Clin Invest. 97:699-705.
4. Weinstein LS, Shenker A, Gejman PV, Merino MJ, Friedman E, Spiegel AM. 1991 Activating mutations of the stimulatory G Protein in the McCune-Albright syndrome. N Engl J Med. 325: 1688-1695.
5. Lacroix A, Bolté E, Tremblay J, et al. 1992 Gastric inhibitory polypeptide-dependent cortisol hypersecretion: a new cause of Cushing's syndrome. N Engl J Med. 327:974-980.
6. Reznik Y, Allali-Zerah V, Chayvialle JA, et al. 1992 Food-dependent Cushing's syndrome mediated by aberrant adrenal sensitivity to gastric inhibitory polypeptide. N Engl J Med. 327:981-986.
7. Archambeaud-Mouveroux F, Comas JM, Tessier MP, et al. Food-dependent Cushing's syndrome associated with the Carney complex. Proc of the 78th Annual Meeting of the Int Endocrine Soc. 1996; 899.
8. Hamet P, Larochelle P, Franks DJ, Cartier P, Bolté E. 1987 Cushing's syndrome with food-dependent periodic hormonogenesis. Clin Invest Med. 10:530-533.
9. De Herder WW, Hofland LJ, Usdin TB, et al. 1996 Food-dependent Cushing's syndrome resulting from abundant expression of gastric inhibitory polypeptide receptors in adrenal adenoma cells. J Clin Endocrinol Metab. 81:3168-3172.
10. Usdin TB, Mezey E, Button DC, Brownstein MJ, Bonner TI. 1993 Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain. Endocrinology. 133:2861-2870.
11. Yasuda K, Inagaki N, Yamada Y, Kubota A, Seino S, Seino Y. 1994 Hamster gastric inhibitory polypeptide receptor expressed in pancreatic islets and clonal insulin-secreting cells; its structure and functional properties. Biochem Biophys Res Commun. 205:1556-1562.
12. Cremlich S, Porret A, Hani EH, et al. 1995 Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor. Diabetes. 44:1202-1208.
13. Yamada Y, Hayami T, Nakamura K, et al. 1995 Human gastric inhibitory polypeptide receptor: cloning of the gene (GIPR) and cDNA. Genomics. 29:773-776.
14. Voltz A, Goke R, Lankat-Buttgereit B, Fehmann HC, Bode HP, Goke B. 1995 Molecular cloning, functional expression, and signal transduction of the GIP-receptor cloned from a human insulinoma. FEBS Lett. 373:23-29.
15. Kaplan AM, Vigna SR. 1994 Gastric inhibitory polypeptide (GIP) binding sites in rat brain. Peptides. 15:297-302.
16. Lacroix A, Tremblay J, Rousseau G, Bouvier M, Hamet P. 1997 Propranolol therapy for ectopic β-adrenergic receptors in adrenal Cushing's syndrome. N Engl J Med. 337:1429-1434.
17. 1-vasopressin receptor in a patient with adrenocorticotropin-independent macronodular adrenal hyperplasia, Cushing's syndrome and orthostatic hypotension. J Clin Endocrinol Metab. 82:2414-2422.
18. Chomczynski P, Sacchi N. 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:156-159.
19. Sanger F, Nicklen S, Coulson A. 1977 DNA sequencing with chain terminating inhibitors. Proc Natl Acad Sci USA. 74:5463-5467.
20. Fehmann HC, Goke R, Goke B. 1995 Cell and molecular biology of the incretin hormones glucagon-like peptide-1 and glucose-dependent insulin releasing polypeptide. Endocr Rev. 16:390-410.
21. Beck B. 1989 Gastric inhibitory polypeptide: a gut hormone with anabolic functions. J Mol Endocrinol. 2:169-174.
22. Amiranoff B, Couvineau A, Vauclin-Jacques N, Laburthe M. 1986 Gastric inhibitory polypeptide receptor in pancreatic beta cells: direct cross-linking, solubilisation and characterization as a glycoprotein. Eur J Biochem. 159:353-358.
23. Maletti M, Altman JJ, Hoa DH. 1987 Evidence of functional gastric inhibitory polypeptide (GIP) receptors in human insulinoma. Binding of synthetic human GIP1-31 and activation of adenylate cyclase. Diabetes. 36:1336-1340.
24. McIntosh CH, Wheeler MB, Gelling RW, Brown JC, Pederson RA. 1996 GIP receptors and signal-transduction mechanisms. Acta Physiol Scand. 157:361-365.
25. Kubota A, Yamada Y, Hayami T, et al. 1996 Identification of two missense mutations in the GIP receptor gene: a functional study and association analysis with NIDDM. Diabetes. 45:1701-1705.
26. Perraudin V, Delarue C, De Keyzer Y, et al. 1995 Vasopressin-responsive adrenocortical tumor in a mild Cushing's syndrome: in vivo and in vitro studies. J Clin Endocrinol Metab. 80:2661-2667.
27. Horiba N, Suda T, Aioba M, et al. 1995 Lysine vasopressin stimulation of cortisol secretion in patients with adreno-corticotropin-independent macronodular adrenal hyperplasia. J Clin Endocrinol Metab. 80:2336-2341.