Propranolol therapy for ectopic β-adrenergic receptors in adrenal Cushing's syndrome

New England Journal of Medicine

Volumn 337, Issue 20, 1997, Pages 1429-1434

  Lacroix, André ^a   Tremblay, Johanne ^a   Rousseau, Guy ^b   Bouvier, Michel ^b   Hamet, Pavel ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPRENOLOL; ARGIPRESSIN; BETA ADRENERGIC RECEPTOR; CISAPRIDE; CORTICOTROPIN RELEASING FACTOR; CYANOPINDOLOL; DESMOPRESSIN; DEXAMETHASONE; GLUCAGON; GONADORELIN; INSULIN; PROPRANOLOL; PROTIRELIN;

ADRENERGIC SYSTEM; ADULT; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; CASE REPORT; CUSHING DISEASE; HEART RATE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; MALE; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RECEPTOR BINDING;

ADRENAL GLANDS; ADRENERGIC BETA-ANTAGONISTS; CATECHOLAMINES; CUSHING SYNDROME; HUMANS; HYDROCORTISONE; HYPERPLASIA; MALE; MIDDLE AGED; PROPRANOLOL; RECEPTORS, ADRENERGIC, BETA;

EID: 0030683972     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199711133372004     Document Type: Article

References (28)

1. Nieman L, Cutler GB Jr. Cushing's syndrome. In: DeGroot LJ, Besser M, Burger HG, et al., eds. Endocrinology. Philadelphia: W.B. Saunders, 1995:1741-69.
2. Lacroix A, Bolté E, Tremblay J, et al. Gastric inhibitory polypeptide-dependent cortisol hypersecretion - a new cause of Cushing's syndrome. N Engl J Med 1992;327:974-80.
3. Reznik Y, Allali-Zerah V, Chayvialle JA, et al. Food-dependent Cushing's syndrome mediated by aberrant adrenal sensitivity to gastric inhibitory polypeptide. N Engl J Med 1992;327:981-6.
4. Archambeaud-Mouveroux F, Comas JM, Tessier MP, et al. Food-dependent Cushing's syndrome associated with the Carney complex. In: Proceedings of the 10th Meeting of the International Endocrine Society, San Francisco, June 12-15, 1996. Bethesda, Md.: Endocrine Society Press, 1996:899. abstract.
5. Hamet P, Larochelle P, Franks DJ, Cartier P, Bolté E. Cushing syndrome with food-dependent periodic hormonogenesis. Clin Invest Med 1987;10: 530-3.
6. de Herder WW, Hofland LJ, Usdin TB, et al. Food-dependent Cushing's syndrome resulting from abundant expression of gastric inhibitory polypeptide receptors in adrenal adenoma cells. J Clin Endocrinol Metab 1996;81:3168-72.
7. N'Diaye N, Tremblay J, de Herder WW, Hamet P, Lacroix A. Adrenal overexpression of gastric inhibitory polypeptide receptor underlies food-dependent Cushing's syndrome. In: Program and abstracts of the 79th Annual Meeting of the Endocrine Society, Minneapolis, June 11-14, 1997. Bethesda, Md.: Endocrine Society Press, 1997:304. abstract.
8. 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): functionality and regulation of the expressed receptors. Mol Pharmacol 1988;33:133-9.
9. Salomon Y, Londos C, Rodbell M. A highly sensitive adenylate cyclase assay. Anal Biochem 1974;58:541-8.
10. Hieble JP, Ruffolo RR. Subclassification of the β-adrenoceptors. Pharmacol Commun 1995;6:183-93.
11. 2-adrenergic receptors in Chinese hamster fibroblasts. Mol Pharmacol 1992;41:542-8.
12. 3-adrenergic receptor. Mol Pharmacol 1993;44:1094-104.
13. 3-adrenergic receptor is resistant to short term agonist-promoted desensitization. Mol Pharmacol 1993;43:548-55.
14. Hinshaw HT, Ney RL. Abnormal hormonal control in the neoplastic adrenal cortex. In: McKerns KW, ed. Hormones and cancer. New York: Academic Press, 1974:309-27.
15. Williams LT, Gore TB, Lefkowitz RJ. Ectopic β-adrenergic receptor binding sites: possible molecular basis of aberrant catecholamine responsiveness of an adrenocortical tumor adenylate cyclase. J Clin Invest 1977; 59:319-24.
16. Matsukura S, Kakita T, Sueoka S, et al. Multiple hormone receptors in the adenylate cyclase of human adrenocortical tumors. Cancer Res 1980; 40:3768-71.
17. Hirata Y, Uchihashi M, Sueoka S, Matsukura S, Fujita T. Presence of ectopic β-adrenergic receptors on human adrenocortical cortisol-producing adenomas. J Clin Endocrinol Metab 1981;53:953-7
18. Katz MS, Kelly TM, Dax EM, Pineyro MA, Partilla JS, Gregerman RI. Ectopic β-adrenergic receptors coupled to adenylate cyclase in human adrenocortical carcinomas. J Clin Endocrinol Metab 1985;60:900-9.
19. Millington DS, Golder MP, Cowley T, et al. In vitro synthesis of steroids by a feminising adrenocortical carcinoma: effect of prolactin and other protein hormones. Acta Endocrinol 1977;59:319-24.
20. Leinonen P, Ranta T, Siegberg R, Pelkonen R, Heikkilä P, Kahri A. Testosterone-secreting virilizing adrenal adenoma with human chorionic gonadotrophin receptors and 21-hydroxylase deficiency. Clin Endocrinol (Oxf) 1991;34:31-5.
21. 1-vasopressin receptor in a patient with adrenocorticotropin-independent macronodular adrenal hyperplasia, Cushing's syndrome, and orthostatic hypotension. J Clin Endocrinol Metab 1997;82:2414-22.
22. Perraudin V, Delarue C, De Keyzer Y, et al. Vasopressin-responsive adrenocortical tumor in a mild Cushing's syndrome: in vivo and in vitro studies. J Clin Endocrinol Metab 1995;80:2661-7
23. Horiba N, Suda T, Aiba M, et al. Lysine vasopressin stimulation of cortisol secretion in patients with adrenocorticotropin-independent macronodular adrenal hyperplasia. J Clin Endocrinol Metab 1995;80:2336-41.
24. Chidiac P, Hebert TE, Valiquette M, Dennis M, Bouvier M. Inverse agonist activity of β-adrenergic antagonists. Mol Pharmacol 1994;45:490-9.
25. 2-adrenergic receptor transcription in human lung. Am J Physiol 1995;268:L41-L46.
26. 2-adrenergic receptor protein and mRNA levels by glucocorticoids during 3T3-F442A adipose differentiation. J Biol Chem 1990;265:16343-9.
27. 2-adrenergic receptor gene are obligate for glucocorticoid regulation of receptor mRNA levels. Biochem Biophys Res Commun 1988;154:676-81.
28. 2-adrenergic receptor and their putative promoter regions. J Biol Chem 1987;262:7321-7.