Rapid PCR detection of Helicobacter pylori-associated virulence and resistance genes directly from gastric biopsy material

Journal of Clinical Microbiology

Volumn 36, Issue 12, 1998, Pages 3689-3690

  Björkholm, Britta ^a,c   Befrits, Ragnar ^a   Jaup, Bernhard ^d   Engstrand, Lars ^b,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

^c UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^d Capio AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; CLARITHROMYCIN; MACROLIDE; RIBOSOME RNA;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM DETECTION; FEMALE; GENE; GENE MUTATION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; STOMACH BIOPSY;

BACTERIA (MICROORGANISMS); HELICOBACTER PYLORI; NEGIBACTERIA;

EID: 0031756570     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/jcm.36.12.3689-3690.1998     Document Type: Article

References (19)

1. Crabtree, J. E., J. D. Taylor, J. I. Wyatt, R. V. Heatley, T. M. Shallcross, D. S. Tompkins, and B. J. Rathbone. 1991. Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology. Lancet 338:332-335.
2. Enroth, H., O. Nyrén, and L. Engstrand. One stomach - one strain: does Helicobacter pylori strain variation influence disease outcome? Dig. Dis. Sci., in press.
3. The European Helicobacter Pylori Study Group. 1997. Current European concepts in the management of Helicobacter pylori infection. The Maastricht Consensus Report. Gut 41:8-13.
4. Falk, P. 1996. Helicobacter pylori - can the mechanisms of pathogenesis guide us towards novel strategies for treatment and prevention? J. Intern. Med. 240:319-332.
5. Figura, N., P. Guglielmetti, A. Rossolini, A. Barberi, G. Cusi, R. A. Musmanno, M. Russi, and S. Quaranta. 1989. Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only. J. Clin. Microbiol. 27:225-226.
6. Graham, D. Y. 1997. Helicobacter pylori infection in the pathogenesis of duodenal ulcer and gastric cancer: a model. Gastroenterology 113:1983-1991.
7. Hammar, M., T. Tyszkiewicz, T. Wadström, and P. W. O'Toole. 1992. Rapid detection of Helicobacter pylori in gastric biopsy material by polymerase chain reaction. J. Clin. Microbiol. 30:54-58.
8. Ho, S.-A., J. A. Hoyle, F. A. Lewis, A. D. Secker, D. Cross, N. P. Mapstone, M. F. Dixon, J. I. Wyatt, D. S. Tompkins, G. R. Taylor, and P. Quirke. 1991. Direct polymerase chain reaction test for detection of Helicobacter pylori in humans and animals. J. Clin. Microhiol. 29:2543-2549.
9. Hultén, K., A. Gibreel, O. Sköld, and L. Engstrand. 1997. Macrolide resistance in Helicobacter pylori: mechanism and stability in strains from clarithromycin-treated patients. Antimicrob. Agents Chemother. 41:2550-2553.
10. Li, C., T. Ha, D. S. Chi, D. A. Ferguson, C. Jiang, J. J. Laffa, and E. Thomas. 1997. Differentiation of Helicobacter pylori strains directly from gastric biopsy specimens by PCR-based restriction fragment length polymorphism analysis without culture. J. Clin. Microbiol. 35:3021-3025.
11. Lind, T., S. Velhuyzen van Zanten, P. Unge, R. Spiller, E. Bayerdörffer, C. O'Morain, K. D. Bardhan, M. Bradette, N. Chiba, M. Wrangstadh, C. Cederberg, and J.-P. Idström. 1996. Eradication of Helicobacter pylori using one week triple therapies combining omeprazol with two antimicrobials: the MACH I study. Helicobacter 1:138-144.
12. Stone, G. G., D. Shortridge, R. K. Flamm, J. Versalovic, J. Beyer, K. Idler, L. Zulawinski, and S. K. Tanaka. 1996. Identification of a 23S rRNA gene mutation in clarithromycin-resistant Helicobacter pylori. Helicobacter 1:227-228.
13. Stone, G. G., D. Shortridge, J. Versalovic, J. Beyer, R. K. Flamm, D. Y. Graham, A. T. Ghoneim, and S. K. Tanaka. 1997. A PCR-oligonucleotide ligation assay to determine the prevalence of 23S rRNA gene mutations in clarithromycin-resistant Helicobacter pylori. Antimicrob. Agents Chemother. 41:712-714.
14. Szczebara, F., L. Dhaenens, P. Vincent, and M. O. Husson. 1997. Evaluation of rapid molecular method for detection of clarithromycin resistance in Helicobacter pylori. Eur. J. Clin. Microbiol. Infect. Dis. 16:162-164.
15. Tummuru, M. K., T. L. Cover, and M. J. Blaser. 1993. Cloning and expression of a high-molecular-mass major antigen of Helicobacler pylori: evidence of linkage to cytotoxin production. Infect. Immun. 61:1799-1809.
16. van der Hulst, R. W. M., J. J. Keller, E. A. J. Rauws, and G. N. J. Tytgat. 1996. Treatment of Helicobacter pylori infection: a review of the world literature. Helicobacter 1:6-19.
17. Versalovic, J., D. Shortridge, K. Kibler, M. V. Griffy, J. Beyer, R. K. Flamm, S. K. Tanaka, D. Y. Graham, and M. F. Go. 1996. Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori. Antimicrob. Agents Chemother. 40:477-480.
18. Wahlfors, J., J. H. Meurman, J. Toskala, A. Korhonen, P. Alakuijala, E. Janatuinen, U. M. Kärkkäinen, P. Nuutinen, and J. Jänne. 1995. Development of a rapid PCR method for identification of Helicobacter pylori in dental plaque and gastric biopsy specimens. Eur. J. Clin. Microbiol. Infect. Dis. 14:780-786.
19. Wang, J. T., J. T. Lin, J. C. Sheu, J. C. Yang, D. S. Chen, and T. H. Wang. 1993. Detection of Helicobacter pylori in gastric biopsy tissue by polymerase chain reaction. Eur. J. Clin. Microbiol. Infect. Dis. 12:367-371.