메뉴 건너뛰기




Volumn 4, Issue 10, 1998, Pages 2545-2550

Cell surface density of p185(c-erbB-2) determines susceptibility to anti-p185(c-erbB-2)-Ricin A chain (RTA) immunotoxin therapy alone and in combination with anti-p170(EGFR)-RTA in ovarian cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; IMMUNOTOXIN; ONCOPROTEIN; RICIN A;

EID: 0031756294     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (26)

References (42)
  • 2
    • 0026023499 scopus 로고
    • Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. Correlation of receptor expression with prognostic factors in patients with ovarian cancer
    • Berchuck, A., Rodriguez, G. C., and Kamel, A. Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. Correlation of receptor expression with prognostic factors in patients with ovarian cancer. Am. J. Obstet. Gynecol., 164: 669-674, 1991.
    • (1991) Am. J. Obstet. Gynecol. , vol.164 , pp. 669-674
    • Berchuck, A.1    Rodriguez, G.C.2    Kamel, A.3
  • 3
    • 0026737848 scopus 로고
    • Expression of epidermal growth factor receptor in normal ovary and in ovarian tumors
    • Stewart, C. J., Owens, O. J., Richmond, J. A., and McNicol, A. M. Expression of epidermal growth factor receptor in normal ovary and in ovarian tumors. Int. J. Gynecol. Pathol., 11: 266-272, 1992.
    • (1992) Int. J. Gynecol. Pathol. , vol.11 , pp. 266-272
    • Stewart, C.J.1    Owens, O.J.2    Richmond, J.A.3    McNicol, A.M.4
  • 4
    • 0023840862 scopus 로고
    • Occurrence of epidermal growth factor receptors in human adnexal tumors and their prognostic value in advanced ovarian carcinomas
    • Bauknecht, T., Runge, M., Schwall, M., and Pfleiderer, A. Occurrence of epidermal growth factor receptors in human adnexal tumors and their prognostic value in advanced ovarian carcinomas. Gynecol. Oncol., 29: 147-157, 1988.
    • (1988) Gynecol. Oncol. , vol.29 , pp. 147-157
    • Bauknecht, T.1    Runge, M.2    Schwall, M.3    Pfleiderer, A.4
  • 5
    • 0027407511 scopus 로고
    • Prognostic significance of HER-2/neu expression in advanced epithelial ovarian cancer: A multivariate analysis
    • Rubin, S. C., Finstad, C. L., Wong, G. Y., Almadrones, L., Plante, M., and Lloyd, K. O. Prognostic significance of HER-2/neu expression in advanced epithelial ovarian cancer: a multivariate analysis. Am. J. Obstet. Gynecol., 168: 162-169, 1993.
    • (1993) Am. J. Obstet. Gynecol. , vol.168 , pp. 162-169
    • Rubin, S.C.1    Finstad, C.L.2    Wong, G.Y.3    Almadrones, L.4    Plante, M.5    Lloyd, K.O.6
  • 7
    • 0029830451 scopus 로고    scopus 로고
    • Overexpression of c-erbB2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1-independent mechanisms
    • Yu, D., Liu, B., Tan, M., Li, J., Wang, S-S., and Hung, M-C. Overexpression of c-erbB2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1-independent mechanisms. Oncogene, 13: 1359-1365, 1996.
    • (1996) Oncogene , vol.13 , pp. 1359-1365
    • Yu, D.1    Liu, B.2    Tan, M.3    Li, J.4    Wang, S.-S.5    Hung, M.-C.6
  • 8
    • 0029919307 scopus 로고    scopus 로고
    • Growth inhibition of breast cancer cell lines by combinations of anti-p185HER2 monoclonal antibody and cytokines
    • Kopreski, M. S., Lipton, A., Harvey, H. A., and Kumar, R. Growth inhibition of breast cancer cell lines by combinations of anti-p185HER2 monoclonal antibody and cytokines. Anticancer Res., 16: 433-436, 1996.
    • (1996) Anticancer Res. , vol.16 , pp. 433-436
    • Kopreski, M.S.1    Lipton, A.2    Harvey, H.A.3    Kumar, R.4
  • 10
    • 0030935529 scopus 로고    scopus 로고
    • An intracellular anti-erb-B-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2
    • Wright, M., Grim, J., Deshane, J., Kim, M., Strong, T. V., Siegal, G. P., and Curiel, D. T. An intracellular anti-erb-B-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2. Gene Ther., 4: 317-322, 1997.
    • (1997) Gene Ther. , vol.4 , pp. 317-322
    • Wright, M.1    Grim, J.2    Deshane, J.3    Kim, M.4    Strong, T.V.5    Siegal, G.P.6    Curiel, D.T.7
  • 11
    • 0024478054 scopus 로고
    • p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor
    • Hudziak, R. M., Lewis, G. D., Winget, M., Fendly, B. M., Shepard, H. M., and Ullrich, A. p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. Mol. Cell. Biol., 9: 1165-1172, 1989.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1165-1172
    • Hudziak, R.M.1    Lewis, G.D.2    Winget, M.3    Fendly, B.M.4    Shepard, H.M.5    Ullrich, A.6
  • 12
    • 0026091927 scopus 로고
    • Mechanistic aspects of the opposing effects of monoclonal antibodies to the ERBB2 receptor on tumor growth
    • Stancovski, I., Hurwitz, E., Leitner, O., Ullrich, A., Yarden, Y., and Sela, M. Mechanistic aspects of the opposing effects of monoclonal antibodies to the ERBB2 receptor on tumor growth. Proc. Natl. Acad. Sci. USA, 88: 8691-8695, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8691-8695
    • Stancovski, I.1    Hurwitz, E.2    Leitner, O.3    Ullrich, A.4    Yarden, Y.5    Sela, M.6
  • 14
    • 0025752933 scopus 로고
    • Selection of monoclonal antibodies which induce internalization and phosphorylation of p185HER2 and growth inhibition of cells with HER2/neu gene amplification
    • Tagliabue, E., Centis, F., Campiglio, M., Mastroianni, A., Martignone, S., Pellegrini, R., Casalini, P., Lanzi, C., Menard, S., and Colnaghi, M. I. Selection of monoclonal antibodies which induce internalization and phosphorylation of p185HER2 and growth inhibition of cells with HER2/neu gene amplification. Int. J. Cancer, 47: 933-937, 1991.
    • (1991) Int. J. Cancer , vol.47 , pp. 933-937
    • Tagliabue, E.1    Centis, F.2    Campiglio, M.3    Mastroianni, A.4    Martignone, S.5    Pellegrini, R.6    Casalini, P.7    Lanzi, C.8    Menard, S.9    Colnaghi, M.I.10
  • 15
    • 0026685034 scopus 로고
    • Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies
    • Kasprzyk, P. G., Song, S. U., Di Fiore, P. P., and King, C. R. Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies. Cancer Res., 52: 2771-2776, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 2771-2776
    • Kasprzyk, P.G.1    Song, S.U.2    Di Fiore, P.P.3    King, C.R.4
  • 16
    • 0027447698 scopus 로고
    • Antibody-induced growth inhibition is mediated through immunochemically and functionally distinct epitopes on the extracellular domain of the c-erbB-2 (HER-2) gene product p185
    • Xu, F. J., Lupu, R., Rodriguez, G. C., Whitaker, R. S., Boente, M. P., Berchuck, A., Yu, Y., DeSombre, K. A., Boyer, C., and Bast, R. C., Jr. Antibody-induced growth inhibition is mediated through immunochemically and functionally distinct epitopes on the extracellular domain of the c-erbB-2 (HER-2) gene product p185. Int. J. Cancer, 53: 401-408, 1993.
    • (1993) Int. J. Cancer , vol.53 , pp. 401-408
    • Xu, F.J.1    Lupu, R.2    Rodriguez, G.C.3    Whitaker, R.S.4    Boente, M.P.5    Berchuck, A.6    Yu, Y.7    DeSombre, K.A.8    Boyer, C.9    Bast Jr., R.C.10
  • 19
    • 0025993767 scopus 로고
    • Requirements for the internalization of a murine monoclonal antibody directed against the HER-2/neu gene product c-erbB-2
    • Maier, L. A., Xu, F. J., Hester, S., Boyer, C., McKenzie, S., Bruskin, A. M., Argnon, Y., and Bast, R. C. Requirements for the internalization of a murine monoclonal antibody directed against the HER-2/neu gene product c-erbB-2. Cancer Res., 51: 5361-5369, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 5361-5369
    • Maier, L.A.1    Xu, F.J.2    Hester, S.3    Boyer, C.4    McKenzie, S.5    Bruskin, A.M.6    Argnon, Y.7    Bast, R.C.8
  • 21
    • 0026486446 scopus 로고
    • Selective inhibition of tumor cell growth by a recombinant single-chain antibody-toxin specific for the erbB-2 receptor
    • Weis, W., Harwerth, I. M., Mueller, M., Groner, B., and Hynes, N. E. Selective inhibition of tumor cell growth by a recombinant single-chain antibody-toxin specific for the erbB-2 receptor. Cancer Res., 52: 6310-6317, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 6310-6317
    • Weis, W.1    Harwerth, I.M.2    Mueller, M.3    Groner, B.4    Hynes, N.E.5
  • 23
    • 0027250834 scopus 로고
    • Characterization of cytotoxic activity of saporin anti-gp185/HER-2 immunotoxins
    • Tecce, R., Digiesi, G., Savarese, A., Trizio, D., and Natali, P. G. Characterization of cytotoxic activity of saporin anti-gp185/HER-2 immunotoxins. Int. J. Cancer, 55: 122-127, 1993.
    • (1993) Int. J. Cancer , vol.55 , pp. 122-127
    • Tecce, R.1    Digiesi, G.2    Savarese, A.3    Trizio, D.4    Natali, P.G.5
  • 24
    • 85045228130 scopus 로고    scopus 로고
    • Coexpression of the C-erbB-2 (HER-2/neu) gene product (P185) and epidermal growth factor receptor (p170) on epithelial ovarian cancers and normal tissues
    • in press
    • Bast, R. C., Jr., Kerns, B. J., MacDonald, J. A., Jordan, P. A., Boyer, C. M., Mendelsohn, J., and Berchuck, A. Coexpression of the C-erbB-2 (HER-2/neu) gene product (P185) and epidermal growth factor receptor (p170) on epithelial ovarian cancers and normal tissues. Hydridoma, in press, 1998.
    • (1998) Hydridoma
    • Bast Jr., R.C.1    Kerns, B.J.2    MacDonald, J.A.3    Jordan, P.A.4    Boyer, C.M.5    Mendelsohn, J.6    Berchuck, A.7
  • 25
    • 0021363327 scopus 로고
    • Growth inhibition of human tumor cells in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies
    • Masui, H., Kawamoto, T., Sato, J. D., Wolf, B., Sato, G., and Mendelsohn, J. Growth inhibition of human tumor cells in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies. Cancer Res., 44: 1002-1007, 1984.
    • (1984) Cancer Res. , vol.44 , pp. 1002-1007
    • Masui, H.1    Kawamoto, T.2    Sato, J.D.3    Wolf, B.4    Sato, G.5    Mendelsohn, J.6
  • 26
    • 0024361386 scopus 로고
    • Cytotoxicity against human tumor cells mediated by the conjugate of anti-epidermal growth factor receptor monoclonal antibody to recombinant ricin A chain
    • Masui, H., Kamrath, H., Apell, G., Houston, L. L., and Mendelsohn, J. Cytotoxicity against human tumor cells mediated by the conjugate of anti-epidermal growth factor receptor monoclonal antibody to recombinant ricin A chain. Cancer Res., 49: 3482-3488, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 3482-3488
    • Masui, H.1    Kamrath, H.2    Apell, G.3    Houston, L.L.4    Mendelsohn, J.5
  • 27
    • 0024586031 scopus 로고
    • Selective killing of squamous carcinoma cells by an immunotoxin that recognizes the EGF receptor
    • Ozawa, S., Ueda, M., Ando, N., Abe, O., Minoshima, S., and Shimizu, N. Selective killing of squamous carcinoma cells by an immunotoxin that recognizes the EGF receptor. Int. J. Cancer, 43: 152-157, 1989.
    • (1989) Int. J. Cancer , vol.43 , pp. 152-157
    • Ozawa, S.1    Ueda, M.2    Ando, N.3    Abe, O.4    Minoshima, S.5    Shimizu, N.6
  • 28
    • 0024819115 scopus 로고
    • Suppression of an epidermal growth factor receptor-hyperproducing tumor by an immunotoxin conjugate of gelonin and a monoclonal anti-epidermal growth factor receptor antibody
    • Hirota, N., Ueda, M., Ozawa, S., Abe, O., and Shimizu, N. Suppression of an epidermal growth factor receptor-hyperproducing tumor by an immunotoxin conjugate of gelonin and a monoclonal anti-epidermal growth factor receptor antibody. Cancer Res., 49: 7106-7109. 1989.
    • (1989) Cancer Res. , vol.49 , pp. 7106-7109
    • Hirota, N.1    Ueda, M.2    Ozawa, S.3    Abe, O.4    Shimizu, N.5
  • 29
    • 0024348697 scopus 로고
    • Generation and characterization of monoclonal antibodies specific for the human neu oncogene product, p185
    • McKenzie, S. J., Marks, P. J., Lam, T., Morgan, J., Panicali, D. L., Trimpe, K. L., and Carney, W. P. Generation and characterization of monoclonal antibodies specific for the human neu oncogene product, p185. Oncogene, 4: 543-548, 1989.
    • (1989) Oncogene , vol.4 , pp. 543-548
    • McKenzie, S.J.1    Marks, P.J.2    Lam, T.3    Morgan, J.4    Panicali, D.L.5    Trimpe, K.L.6    Carney, W.P.7
  • 30
    • 0021979012 scopus 로고
    • Evaluation of monoclonal antibodies for the development of breast cancer immunotoxins
    • Bjorn, M. J., Ring, D., and Frankel, A. Evaluation of monoclonal antibodies for the development of breast cancer immunotoxins. Cancer Res., 45: 1214-1221, 1985.
    • (1985) Cancer Res. , vol.45 , pp. 1214-1221
    • Bjorn, M.J.1    Ring, D.2    Frankel, A.3
  • 31
    • 0025768227 scopus 로고
    • Identity of BCA200, and c-erbB-2 indicated by reactivity of monoclonal antibodies with recombinant c-erbB-2
    • Ring, D. B., Clark, R., and Saxena, A. Identity of BCA200, and c-erbB-2 indicated by reactivity of monoclonal antibodies with recombinant c-erbB-2. Mol. Immunol., 28: 915-917, 1991.
    • (1991) Mol. Immunol. , vol.28 , pp. 915-917
    • Ring, D.B.1    Clark, R.2    Saxena, A.3
  • 32
    • 0024361386 scopus 로고
    • Cytotoxicity against human tumor cells mediated by the conjugate of anti-epidermal growth factor receptor monoclonal antibody to recombinant ricin A chain
    • Masui, H., Kamrath, H., Apell, G., Houston, L. L., and Mendelsohn, J. Cytotoxicity against human tumor cells mediated by the conjugate of anti-epidermal growth factor receptor monoclonal antibody to recombinant ricin A chain. Cancer Res., 49: 3482-3488, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 3482-3488
    • Masui, H.1    Kamrath, H.2    Apell, G.3    Houston, L.L.4    Mendelsohn, J.5
  • 34
    • 0017874586 scopus 로고
    • Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril
    • Fraker, P. J., and Speck, J. C., Jr. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril. Biochem. Biophys. Res. Commun., 80: 849-857, 1978.
    • (1978) Biochem. Biophys. Res. Commun. , vol.80 , pp. 849-857
    • Fraker, P.J.1    Speck Jr., J.C.2
  • 35
    • 0002463316 scopus 로고
    • The Spearman estimator for serial dilution assays
    • Johnson, E. A., and Brown, B. W. The Spearman estimator for serial dilution assays. Biometrics, 27: 79-88, 1961.
    • (1961) Biometrics , vol.27 , pp. 79-88
    • Johnson, E.A.1    Brown, B.W.2
  • 36
    • 0018425119 scopus 로고
    • Exploitable mechanisms in combined radiotherapy-chemotherapy: The concept of additivity
    • Steel, G. G., and Peckham, M. J. Exploitable mechanisms in combined radiotherapy-chemotherapy: the concept of additivity. Int. J. Radiat. Oncol. Biol. Phys., 5: 85-91, 1979.
    • (1979) Int. J. Radiat. Oncol. Biol. Phys. , vol.5 , pp. 85-91
    • Steel, G.G.1    Peckham, M.J.2
  • 39
    • 0028997307 scopus 로고
    • HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells
    • Pietras, R. J., Arboleda, J., Reese, D. M., Wongvipat, N., Pegram, M. D., Ramos, L., Parker, M. G., Sliwkowski, M. X., and Slamon, D. J. HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells. Oncogene, 10: 2435-2446, 1995.
    • (1995) Oncogene , vol.10 , pp. 2435-2446
    • Pietras, R.J.1    Arboleda, J.2    Reese, D.M.3    Wongvipat, N.4    Pegram, M.D.5    Ramos, L.6    Parker, M.G.7    Sliwkowski, M.X.8    Slamon, D.J.9
  • 40
    • 0030792410 scopus 로고    scopus 로고
    • MDA 468 growth inhibition by EGF is associated with the induction of the cyclin-dependent kinase inhibitor p21WAF1
    • Xie, W., Su, K., Wang, D., Paterson, A. J., and Kudlow, J. E. MDA 468 growth inhibition by EGF is associated with the induction of the cyclin-dependent kinase inhibitor p21WAF1. Anticancer Res., 17: 2627-2633, 1997.
    • (1997) Anticancer Res. , vol.17 , pp. 2627-2633
    • Xie, W.1    Su, K.2    Wang, D.3    Paterson, A.J.4    Kudlow, J.E.5
  • 41
    • 0025993767 scopus 로고
    • Requirements for the internalization of a murine monoclonal antibody directed against the HER-2/neu gene product c-erb-B-2
    • Maier, L., Xu, F-J., Hester, S., Boyer, C. M., McKenzie, S., Bruskin, A. M., Argon, Y., and Bast, R. C. Requirements for the internalization of a murine monoclonal antibody directed against the HER-2/neu gene product c-erb-B-2. Cancer Res., 51: 5361-5369, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 5361-5369
    • Maier, L.1    Xu, F.-J.2    Hester, S.3    Boyer, C.M.4    McKenzie, S.5    Bruskin, A.M.6    Argon, Y.7    Bast, R.C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.