The stress response and the lung

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 273, Issue 1 17-1, 1997, Pages

  Wong, Hector R ^a   Wispé, Jonathan R ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Heat shock; Heat shock protein 70; Home oxygenase; Inducible nitric oxide synthase; Lung injury; Nuclear factor B; Oxidant injury; Stress protein regulation; Stress proteins; Surfactant proteins

Indexed keywords

HEAT SHOCK PROTEIN 70; HEME OXYGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ASTHMA; CONTROLLED STUDY; HEAT SHOCK; HEAT STRESS; HOST RESISTANCE; INFLAMMATION; LUNG INJURY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; REVIEW;

EID: 0030788030     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1997.273.1.l1     Document Type: Review

References (94)

1. Abraham, N. G., Y. Lavrovsky, M. L. Schwartzman, R. A. Stoltz, R. D. Levere, M. E. Gerritsen, S. Shibahara, and A. Kappas. Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity. Proc. Natl. Acad. Sci. USA 92: 6798-6802, 1995.
2. Abravaya, K., M. P. Myers, S. P. Murphy, and R. I. Morimoto. The human heat-shock protein hsp 70 interacts with HSF, the transcription factor that regulates heat-shock gene expression. Genes Dev. 6: 1153-1164, 1992.
3. Alam, J., S. Camhi, and A. M. K. Choi. Identification of a second 5′ distal region that functions as a basal and inducer-dependent transcriptional enhancer of the mouse heme oxygenase-1 gene. J. Biol. Chem. 267: 11977-11984, 1995.
4. Alam, J., and D. Zhining. Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene. J. Biol. Chem. 267: 21894-21900, 1992.
5. Amin, J., J. Ananthan, and R. Voellmy. Key features of heat shock regulatory elements. Mol. Cell. Biol. 8: 3761-3769, 1988.
6. Anathan, J., A. L. Golberg, and R. Voellmy. Abnormal proteins serve as eukaryotic stress signals and trigger the activation of heat shock genes. Science 232: 252-254, 1986.
7. Aucoin, M. M., R. Barhoumi, D. T. Kochevar, H. J. Granger, and R. C. Burghardt. Oxidative injury of coronary endothelial cells depletes intracellular glutathione and induces HSP 70 mRNA. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H1651-H1658, 1995.
8. Baldwin, A. S., Jr. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14: 649-681, 1996.
9. Barnes, P. J., and M. G. Belvisi. Nitric oxide and lung disease. Thorax 48: 1034-1043, 1993.
10. Beckman, R. P., L. E. Mizzen, and W. J. Welch. Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly. Science 248: 850-854, 1990.
11. Bellmann, K., A. Wenz, J. Radons, V. Burkart, R. Leemann, and H. Kolb. Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro. J. Clin. Invest. 95: 2840-2845, 1995.
12. Blake, M. J., D. J. Buckley, and A. R. Buckley. Dopaminergic regulation of heat shock protein-70 in adrenal gland and aorta. Endocrinology 132: 1063-1070, 1993.
13. Blake, M. J., D. Gershon, J. Fargnoli, and N. J. Holbrook. Discordant expression of heat shock protein mRNAs in tissues of heat-stressed rats. J. Biol. Chem. 265: 15275-15279, 1990.
14. Blake, M. J., R. Udelsman, G. J. Feulner, D. D. Norton, and N. J. Holbrook. Stress induced heat shock protein 70 expression in adrenal cortex: an adrenocorticotropic hormone-sensitive, age-dependent response. Proc. Natl. Acad. Sci. USA 88: 9873-9877, 1991.
15. Bonay, M., P. Soler, M. Riquet, J. P. Battesti, A. J. Hance, and A. Tazi. Expression of heat shock proteins in human lung and lung cancers. Am. J. Respir. Cell Mol. Biol. 10: 453-461, 1994.
16. Bond, U., and M. J. Schlesinger. Ubiquitin is a heat shock protein in chicken embryo fibroblasts. Mol. Cell. Biol. 5: 949-956, 1986.
17. Brandes, M. E., and J. N. Finkelstein. Induction of the stress response by isolation of rabbit type II pneumocytes. Exp. Lung Res. 15: 93-111, 1989.
18. Buchman, T. G., P. A. Abello, E. H. Smith, and G. B. Bulkley. Induction of heat shock response leads to apoptosis in endothelial cells previously exposed to endotoxin. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H165-H170, 1993.
19. Buchman, T. G., and D. E. Cabin. Molecular biology of circulatory shock III: HepG2 cells demonstrate two patterns of shock-induced gene expression which are independent, exclusive, and prioritized. Surgery 108: 902-911, 1990.
20. Burdon, R. H. Heat shock and the heat shock proteins. Biochem. J. 240: 313-324, 1986.
21. Cahil, C. M., W. R. Waterman, Y. Xie, P. E. Auron, and S. K. Calderwood. Transcriptional repression of the prointerleukin-1β gene by heat shock factor 1. J. Biol. Chem. 271: 24874-24879, 1996.
22. Camhi, S. L., J. Alam, L. Otterbein, S. L. Sylvester, and A. M. K. Choi. Induction of heme oxygenase-1 gene expression by lipopolysaccharide is mediated by AP-1 activation. Am. J. Respir. Cell Mol. Biol. 13: 387-398, 1995.
23. Choi, A. M. K., and J. Alam. Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury. Am. J. Respir. Cell Mol. Biol. 15: 9-19, 1996.
24. Choi, A. M. K., S. Sylvester, L. Otterbein, and N. J. Holbrook. Molecular responses to hyperoxia in vivo: relationship to increased tolerance in aged rats. Am. J. Respir. Cell Mol. Biol. 13: 74-82, 1995.
25. Cohen, D. S., E. Palmer, W. J. Welch, and D. Sheppard. The response of guinea pig airway epithelial cells and alveolar macrophages to environmental stress. Am. J. Respir. Cell Mol. Biol. 5: 133-143, 1991.
26. Deitch, E. A., S. C. Beck, N. C. Cruz, and A. De Maio. Induction of heat shock gene expression in colonic epithelial cells after incubation with Escherichia coli or endotoxin. Crit. Care Med. 23: 1371-1376, 1995.
27. deVera, M. E., Y. M. Kim, H. R. Wong, Q. Wang, T. R. Billiar, and D. A. Geller. Heat shock inhibits cytokine-inducible nitric oxide synthase expression in rat hepatocytes. Hepatology 24: 1238-1245, 1996.
28. deVera, M. E., J. M. Wong, J. Y. Zhou, E. Tzeng, H. R. Wong, T. R. Billiar, and D. A. Geller. Cytokine-induced nitric oxide synthase gene transcription is blocked by the heat shock response in human liver cells. Surgery 120: 144-149, 1996.
29. Fargnoli, J., T. Kunisada, A. J. Fornace, Jr., E. L. Schneider, and N. J. Holbrook. Decreased expression of heat shock protein 70 mRNA and protein after heat treatment in cells of aged rats. Proc. Natl. Acad. Sci. USA 87: 846-850, 1990.
30. Feinstein, D. L., E. Galea, D. A. Aquino, G. C. Li, H. Xu, and D. J. Reis. Heat shock protein 70 suppresses astroglial-inducible nitric oxide synthase expression by decreasing NF-κB activation. J. Biol. Chem. 271: 17224-17232, 1996.
31. Flanagan, S. W., A. J. Ryan, C. V. Gisolfi, and P. L. Moseley. Tissue-specific HSP70 response in animals undergoing heat stress. Am. J. Physiol. 268 (Regulatory Integrative Comp. Physiol. 37): R28-R32, 1995.
32. Freeman, B. A. Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives. J. Biol. Chem. 269: 26066-26075, 1994.
33. Georgopoulos, C., and W. J. Welch. Role of the major heat shock proteins as molecular chaperones. Annu. Rev. Cell Biol. 9: 601-634, 1993.
34. Gerner, E. W., and M. J. Schneider. Induced thermal resistance in HeLa cells. Nature 256: 500-502, 1975.
35. Hauser, G. J., E. K. Dayao, K. Wasserloos, B. R. Pitt, and H. R. Wong. Heat shock protein induction inhibits inducible nitric oxide synthase mRNA expression and attenuates hypotension in endotoxin-challenged rats. Am. J. Physiol. 271 (Heart Circ. Physiol. 40): H2529-H2535, 1996.
36. Huot, J., F. Houle, D. R. Spitz, and J. Landry. HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress. Cancer Res. 56: 273-279, 1995.
37. Jäätelä, M., D. Wissing, P. A. Bauer, and G. C. Li. Major heat shock protein hsp70 protects tumor cells from tumor necrosis factor cytotoxicity. EMBO J. 11: 3507-3512, 1992.
38. Jornot, L., M. E. Mirault, and A. F. Junod. Differential expression of hsp70 stress proteins in human endothelial cells exposed to heat shock and hydrogen peroxide. Am. J. Respir. Cell Mol. Biol. 5: 265-275, 1991.
39. Keyse, S. M., and R. M. Tyrrell. Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Pros. Natl. Acad. Sci. USA 86: 99-103, 1989.
40. Kindas-Mügge, I., W. R. Pohl, E. Zavadova, H. D. Köhn, S. Fitzal, F. Kummer, and M. Micksche. Alveolar macrophages of patients with adult respiratory distress syndrome express high levels of heat shock protein 72 mRNA. Shock 5: 184-189, 1996.
41. Lanks, K. W. Modulators of the eukaryotic heat shock response. Exp. Cell Res. 165: 1-10, 1986.
42. Lee, P. J., J. Alam, S. L. Sylvester, N. Inamdar, L. Otterbein, and A. M. K. Choi. Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury. Am. J. Respir. Cell Mol. Biol. 13: 387-398, 1996.
43. Lee, P. J., J. Alam, G. W. Wiegand, and A. M. K. Choi. Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia. Proc. Natl. Acad. Sci. USA 93: 10393-10398, 1996.
44. Li, G. C. Induction of thermotolerance and enhanced heat shock protein synthesis in Chinese hamster fibroblasts by sodium arsenite and ethanol. J. Cell. Physiol. 115: 116-122, 1983.
45. Li, G. C., L. Li., Y.-K. Liu, J. Y. Mak, L. Chen, and W. M. F. Lee. Thermal response of rat fibroblasts stably transfected with human 70-kD heat shock protein-encoding gene. Proc. Natl. Acad. Sci. USA 89: 2036-2040, 1992.
46. Li., G. C., and Z. Werb. Correlation between synthesis of heat shock proteins and development of thermotolerance in Chinese hamster fibroblasts. Proc. Natl. Acad. Sci. USA 89: 3218-3222, 1982.
47. Lindquist, S. C. The heat shock response. Annu. Rev. Biochem. 55: 1151-1191, 1986.
48. Lis, J., and C. Wu. Protein traffic on the heat shock promoter: parking, stalling, and trucking along. Cell 74: 1-4, 1993.
49. Maines, M. D. Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J. 2: 2557-2568, 1988.
50. Marber, M. S., R. Mestril, S. H. Chi, M. R. Sayen, D. M. Yellon, and W. H. Dillman. Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J. Clin. Invest. 95: 1446-1456, 1995.
51. Mehlen, P., X. Preville, P. Chareyron, J. Briolay, R. Klemenz, and A. P. Arrigo. Constitutive expression of human hsp27, Drosophila hsp27, or human αB-Crystallin confers resistance to TNF- and oxidative stress-induced cytotoxicity in stably transfected murine L929 fibroblasts. J. Immunol. 154: 363-374, 1995.
52. Minowada, G., and W. J. Welch. Clinical implications of the stress response. J. Clin. Invest. 95: 3-12, 1995.
53. Okuzawa, K., B. Franzen, J. Lindholm, S. Linder, T. Hirano, T. Bergman, Y. Ebihara, H. Kato, and G. Auer. Characterization of gene expression in clinical lung cancer materials by two-dimensional polyacrylamide gel electrophoresis. Electrophoresis 15: 383-390, 1994.
54. Otterbein, L., S. Sylvester, and A. M. K. Choi. Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygenase-1. Am. J. Respir. Cell Mol. Biol. 13: 595-601, 1995.
55. Pelham, H. R. B. A regulatory upstream promoter element in the Drosophila hsp70 heat-shock gene. Cell 30: 517-528, 1982.
56. Pelham, H. R. B. Activation of heat shock genes in eukaryotes. Trends Genet. 1: 31-35, 1985.
57. Pelham, H. R. B. Speculations on the functions of major heat shock and glucose-regulated proteins. Cell 46: 959-961, 1986.
58. Perisic, O. Stable binding of Drosophila heat shock factor to head-to-head and tail-to-tail repeats of a conserved 5 bp recognition unit. Cell 59: 797-806, 1989.
59. Plesset, J., C. Palm, and C. S. McLaughlin. Induction of heat shock proteins and thermotolerance by ethanol in Saccharomyces cervisiae. Biochem. Biophys. Res. Commun. 108: 1340-1345, 1982.
60. Plumier, J.-C. L., B. M. Ross, R. W. Currie, C. E. Angelidis, H. Kazlaris, G. Kollias, and G. N. Pagoulatos. Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery. J. Clin. Invest. 95: 1854-1860, 1995.
61. Riabolow, K. T., L. A. Mizzen, and W. J. Welch. Heat shock is lethal to fibroblasts microinjected with antibodies against hsp70. Science 242: 433-436, 1989.
62. Riberio, S. P., E. Chu, and A. S. Slutsky. Heat stress after injection of LPS in rats decreases mortality (Abstract). Am. J. Respir. Crit. Care Med. 153: A252, 1996.
63. Ribeiro, S. P., J. Villar, G. P. Downey, J. D. Edelson, and A. S. Slutsky. Sodium arsenite induces heat shock protein-72 kilodalton expression in the lungs and protects rats against sepsis. Crit. Care Med. 22: 922-929, 1994.
64. Ribeiro, S. P., J. Villar, G. P. Downey, J. D. Edelson, and A. S. Slutsky. Effects of the stress response in septic rats and LPS-stimulated alveolar macrophages: evidence for TNF-α post-translational regulation. Am. J. Respir. Crit. Care Med. 154: 1843-1850, 1996.
65. Rinaldo, J. E., M. Gorry, R. Strieter, H. Cowan, R. Abdolrasulnia, and V. Shepard. Effect of endotoxin-induced cell injury on 70-kD heat shock proteins in bovine lung endothelial cells. Am. J. Respir. Cell Mol. Biol. 3: 207-216, 1990.
66. Ritossa, F. M. A new puffing pattern induced by a temperature shock and DNP in Drosophila. Experientia 18: 571-573, 1962.
67. Schmidt, J. A., and E. Abdulla. Down-regulation of IL-1β biosynthesis by inducers of the heat-shock response. J. Immunol. 141: 2027-2034, 1988.
68. Schoeniger, L. O., P. M. Reilly, G. B. Bulkley, and T. G. Buchman. Heat-shock gene expression excludes hepatic acute-phase gene expression after resuscitation from hemorrhagic shock. Surgery 112: 355-363, 1992.
69. Simon, M. M., A. Reikerstorfer, A. Schwarz, C. Kronis, T. A. Luger, M. Jäätelä, and T. Schwarz. Heat shock protein 70 overexpression affects the response to ultraviolet light in murine I fibroblasts. J. Clin. Invest. 95: 926-933, 1995.
70. Smith, T. J., G. S. Drummond, I. A. Kourides, and A. Kappas. Thyroid hormone regulation of heme oxidation in the liver. Proc. Natl. Acad. Sci. USA 79: 7537-7541, 1982.
71. Snyder, Y. L., L. Guthrie, G. F. Evans, and S. Zuckerman. Transcriptional inhibition of endotoxin-induced monokine synthesis following heat shock in murine peritoneal macrophages. J. Leukoc. Biol. 51: 181-187, 1992.
72. Spitz, D. R., W. C. Dewey, and G. C. Li. Hydrogen peroxide or heat shock induces resistance to hydrogen peroxide in chinese hamster fibroblasts. J. Cell. Physiol. 131: 364-373, 1987.
73. Strand, C., J. B. Warshaw, K. Snow, and H. C. Jacobs. Heat shock does not induce tolerance to hyperoxia. Lung 172: 79-89, 1994.
74. Tom, D. J., P. A. Rodgers, V. Shokoohi, D. K. Stevenson, and P. A. Dennery. Hepatic heme oxygenase is inducible in neonatal rats during the early postnatal period. Pediatr. Res. 40: 288-293, 1996.
75. Tsukeda, H., H. Maekawa, S. Izumi, and K. Nitta. Effect of heat shock on protein synthesis by normal and malignant human lung cells in tissue culture. Cancer Res. 41: 5188-5192, 1981.
76. Udelsman, R., M. J. Blake, and N. J. Holbrook. Molecular response to surgical stress: specific and simultaneous heat shock protein induction in the adrenal cortex, aorta, and vena cava. Surgery 110: 1125-1131, 1991.
77. Udelsman, R., M. J. Blake, C. A. Stagg, D. G. Li, D. J. Putney, and N. J. Holbrook. Vascular heat shock protein expression in response to stress. Endocrine and autonomic regulation of this age-dependent response. J. Clin. Invest. 91: 465-473, 1993.
78. Vignola, A. M., P. Chanez, B. S. Polla, P. Vic, P. Godard, and J. Bousquet. Increased expression of heat shock protein 70 on airway cells in asthma and chronic bronchitis. Am. J. Respir. Cell Mol. Biol. 13: 683-691, 1995.
79. Vile, G. F., S. Basu-Modak, C. Waltner, and R. M. Tyrell. Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts. Proc. Natl. Acad. Sci. USA 91: 2607-2610, 1994.
80. Villar, J., J. D. Edelson, M. Post, J. B. Mullen, and A. S. Slutsky. Induction of heat stress proteins is associated with decreased mortality in an animal model of acute lung injury. Am. Rev. Respir. Dis. 147: 177-181, 1993.
81. Villar, J., S. P. Ribeiro, J. B. M. Mullen, M. Kuliszewski, M. Post, and A. S. Slutsky. Induction of the heat shock response reduces mortality rate and organ damage in a sepsis-induced acute lung injury model. Crit. Care Med. 22: 914-922, 1994.
82. Volm, M., R. Koomagi, J. Mattern, and G. Stammler. Heat shock (hsp70) and resistance proteins in non-small cell lung carcinomas. Cancer Lett. 95: 195-200, 1995.
83. Waddell, T. K., T. Hirai, J. Piovesan, T. Oka, J. D. Puskas, G. A. Patterson, and A. S. Slutsky. The effect of heat shock on immediate post-preservation lung function. Clin. Invest. Med. 17: 405-413, 1994.
84. Wang, J. R., X. Z. Xiao, S. N. Huang, F. J. Luo, J. L. You, H. Luo, and Z. Y. Luo. Heat shock pretreatment prevents hydrogen peroxide injury of pulmonary endothelial cells and macrophages in culture. Shock 6: 134-141, 1996.
85. Weaver, T. E., and J. A. Whitsett. Structure and function of pulmonary surfactant proteins. Semin. Perinatol. 12: 213-220, 1988.
86. Welch, W. J. Mammalian stress response: cell physiology structure/function of stress proteins, and implications for medicine and disease. Physiol. Rev. 72: 1063-1081, 1992.
87. Whitsett, J. A., L. M. Nogee, T. E. Weaver, and A. D. Horowitz. Human surfactant protein B: structure, function, regulation, and genetic disease. Physiol. Rev. 75: 749-757, 1995.
88. Williams, R. S., J. A. Thomas, M. Fina, Z. German, and I. J. Benjamin. Human heat shock protein 70 (hsp70) protects murine cells from injury during metabolic stress. J. Clin. Invest. 92: 503-508, 1993.
89. Wong, H. R., J. D. Finder, K. Wasserloos, and B. R. Pitt. Expression of inducible nitric oxide synthase in cultured rat pulmonary artery smooth muscle cells is inhibited by the heat shock response. Am. J. Physiol. 269 (Lung Cell. Mol. Physiol. 13): L843-L848, 1995.
90. Wong, H. R., R. J. Mannix, J. M. Rusnak, A. Boota, H. Zar, S. C. Watkins, J. S. Lazo, and B. R. Pitt. The heat shock response attenuates lipopolysaccharide-mediated apoptosis in cultured sheep pulmonary artery endothelial cells. Am. J. Respir. Cell Mol. Biol. 15: 745-751, 1996.
91. Wong, H. R., M. Ryan, S. Gebb, and J. R. Wispé. Selective and transient in vitro effects of heat shock on alveolar type II cell gene expression. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L132-L138, 1997.
92. Wong, H. R., M. Ryan, and J. R. Wispé. The heat shock response inhibits activation of inducible nitric oxide synthase gene expression by blocking I-κB degradation and NF-κB nuclear translocation. Biochem. Biophys. Res. Commun. 231: 257-263, 1997.
93. Wong, H. R., M. Ryan, and J. R. Wispé. Stress response decreases NF-κB nuclear translocation and increases I-κBα expression in A549 cells. J. Clin. Invest. 99: 2423-2428, 1997.
94. Yost, H. J., and S. Lindquist. RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis. Cell 45: 185-193, 1986.