Autologous Transplantation with Tumor-Free Graft: A Model for Multiple Myeloma Patients

Leukemia and Lymphoma

Volumn 23, Issue 42067, 1996, Pages 203-212

  Gazitt, Yair ^a   Reading, Chris L ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

autologous transplantation; minimal residual disease; multiple myeloma; tumor free graft

Indexed keywords

CD34 ANTIGEN; CYCLOPHOSPHAMIDE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

AUTOTRANSPLANTATION; BLOOD CELL; BONE MARROW TRANSPLANTATION; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CELL SELECTION; CELL TRANSPLANTATION; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MINIMAL RESIDUAL DISEASE; MULTIPLE MYELOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVIEW; STEM CELL TRANSPLANTATION; TUMOR CELL;

BONE MARROW TRANSPLANTATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MULTIPLE MYELOMA; TRANSPLANTATION, AUTOLOGOUS;

EID: 0030472562     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428199609054822     Document Type: Article

References (65)

1. Deisseroth A. B., Zu Z., Claxton D., Hanania E., Fu S., Ellerson D., Goldberg L., Thomas M., Janicek K., Anderson W. F., Hester J., Korbling M., Durett A., Moen R., Berebson S., Heimheld S., Hamer J., Calvert L., Tibbits P., Talpaz M., Kantarijian H., Champlin R., Reading C. Genetic marking shows that Ph+ cells present in autologous transplants of CML contribute to relapse after ABMT in CML. Blood 1994; 83: 3068 – 3076
2. Brenner M. K., Rill D. R., Moen R. C., Krance R. A., Mirro J., Anderson W. F., Ihle J. N. Gene-marking to trace origin of relapse after autologous bone marrow transplantation. Lancet 1993; 341: 85 – 86
3. Brugger W., Mocklin W., Heimfeld S., Berenson R. J., Mertelsman R., Kanz L. Ex-vivo expansion of peripheral blood CD34+ cells by stem cell factor IL-1b, IL-6, IL-3, INFg and Epo. Blood 1993; 81: 2579 – 2584
4. Brugger W., Heimfeld S., Berenson R. J., Mertelsman R., Kanz L. Reconstitution of hematopoiesis after high dose chemotherapy by autologous progenitor cells generated ex-vivo. New Engl. J. Med. 1995; 333: 283 – 287
5. Moss T. J., Raynolds P., Sather H. N., Romansky S. G., Hammond D. G., Seeger R. C. Prognostic value of immnocytochemical detection of bone metastases in neuroblastoma. N. Engl. J. Med. 1991; 324: 219 – 224
6. Gazitt Y., Cantor A., He Y-J., Koza S., Cohen R. J., Graham-Pole J. Prognostic factors in purged marrow from patients with neuroblastoma receiving myeloablative treatment: Tumor cell number, N-myc protein, N-myc gene amplification and rate of hematologic recovery. Int. J. Oncol., 3: 755 – 761
7. Leonard R. C., Duncan L. W., Hay F. G. Immunocytochemical detection of residual marrow disease at clinical remission predicts metastatic relapse in small cell lung cancer. Cancer Res. 1990; 50: 6545 – 6548
8. Poro G., Mennard S., Taglibue E., Orefice S., Salvadori B., Squicciari P., Andreola S., Rieke F., Colangi M. Monoclonal antibody detection of carcinoma cells in bone marrow specimens from breast cancer patients. Cancer 1988; 61: 2407 – 2411
9. Sharp J. G., Joshi S. S., Armitage J. O., Bierman P., Coccia P. F., Harrington D. S., Kessinger A., Crouse D. A., Mann S. L., Weisenburger D. D. Significance of detection of occult non-Hodgkin's lymphoma in histologically uninvolved bone marrow by a culture technique. Blood 1992; 79: 1074 – 1080
10. Richman C. M., Weiner R. S., Yankee R. A. Increase in the circulation of stem cells following chemotherapy in man blood. Blood, 47: 1031 – 1039
11. Kessinger A., Armitage J. O., Landmark J. D., Smith D. M., Weisenburger D. Autologous peripheral blood hematopoietic stem cells transplantation restores hematopoietic function following marrow ablative therapy. Blood, 71: 723 – 727
12. Pettengell R., Testa N., Swindell R., Crowther D., Dexter T. Transplantation potential of hematopoietic cells released into the circulation during routine chemotherapy for non-Hodgkin's lymphoma. Blood 1992; 82: 2239 – 2248
13. Molineux G., Pojda Z., Hampson I. N., Lord B. I., Dexter T. M. Transplantation potential of peripheral blood stem cells induced by granulocyte colony stimulating factor. Blood 1990; 76: 2153 – 2158
14. Gianni A. M., Siena S., Bregni M., Tarella C., Stern A. C., Pileri A., Bonadonna G. Granulocyte-macrophage colony-stimulating factor to harvest circulating hematopoietic stem cells for autotransplantation. Lancet 1989; 2: 580 – 584
15. Peters W. P., Rosner G., Ross M., Vredenburgh J., Meisenberg B., Gilbert C., Kurtzberg J. Comparative effect of GM-CSF and G-CSF on priming of peripheral blood progenitor cells for use with autologous marrow after high dose chemotherapy. Blood 1993; 81: 1709 – 1719
16. Haas R., Dick Ho A., Bredthauer U., Cayeux S., Egerer G., Knauf W., Hunstein W. Successful autologous transplantation of blood stem cells mobilized with mrecombinant human granulocyte-macrophage colony stimulating factor. Exp. Hematol. 1990; 18: 94 – 98
17. McNiece I., Langley K. E., Zsebo R. M. Recombinant stem cell factor synergize with GM-CSF. G-CSF, IL-3 and Epo to stimulate human progenitor cells of the myeloid and erythroid lineages. Exp. Hematol. 1992; 19: 226 – 231
18. Williams S. F., Bitran J. D., Richards J. M., Dechristopher P. J., Barker E., Conant J., Golomb H. M., Orlina A. R. Peripheral blood derived stem cells collections in use for autologous transplantation after high-dose chemotherapy: An alternative approach. Bone Marrow Transplant. 1990; 5: 129 – 135
19. Bik To L., Shepperd K. M., Haylock D. M., Dyson P. G., Charles P., Thorp D. L., Dale B. M., Dart G. W., Roberts M. M., Sage R. E., Juttner C. A. Single high dose of cyclophosphamide enable the collection of high numbers of hematopoietic stem cells from peripheral blood. Exp. Hematol. 1990; 18: 442 – 447
20. Kotasek D., Shepherd K. M., Sage R. E., Dale B. M., Norman J. E., Charles P., Gregg A., Pillow A., Bolton A. Factors affecting blood stem cell collections following high-dose cyclophosphamide mobilization in lymphoma, myeloma and solid tumors. Bone Marrow Transplant. 1992; 9: 11 – 19
21. Fermand J., Chervet S., Ravaud P., Divine M., Leblond V., Dreyfus F., Mariette X., Bruet J-C. High dose chemoradiotherapy and autologous blood stem cell transplantation in multiple myeloma. Blood 1993; 82: 2005 – 2009
22. Brugger W., Frisch J., Schulz G., Pressler K., Mertelsman R., Kanz L. Sequential administration of IL-3 and GM-CSF following standard-dose combination chemotherapy with etoposide, ifosfamide and cis-platin. J. Clin. Oncol. 1992; 10: 1452 – 1459
23. Jagannath S., Vesole D., Glenn L., Crowley J., Barlogie B. Low-risk intensive therapy for multiple myeloma with combined autologous bone marrow and blood cell support. Blood 1992; 80: 1666 – 1672
24. Ossenkoppele G. J., Jonkhoff A. R., Huijgens P. C., Nauta J. J. P., Van Der Hem K. G., Drager A. M., Langenhuijsen M. M. A. C. Peripheral blood progenitors mobilized by G-CSF and reinfused as unprocessed autologous whole blood shorten the pancytopenic period following high dose melphalan in multiple myeloma. Bone Marrow Transplant. 1994; 13: 37 – 41
25. Gazitt Y., Reading C. C., Hoffman R., Lee J-H., Vickrema A., Vesole D. H., Jagannath S., Condino J., Lee B., Barlogie B., Tricot G. Purified CD34+Lin-Thy+ stem cells do no contain clonal myeloma cells. Blood 1995; 86: 381 – 389
26. Tricot G., Gazitt Y., Jagannath S., Vesole D., Reading C., Juttner C., Hoffmann R., Barlogie B. CD34+Lin-Thy+ peripheral blood stem cells effect timely trilineage engraftment in multiple myeloma. Blood 1995; 86: 836a
27. Desikan K. R., Jagannath S., Vesole D., Bracy D., Nelson J., Tindel S., Barlogie B., Tricot G. Collection of peripheral blood stem cells in multiple myeloma following G-CSF with or without high dose cyclophosphamide. Blood 1995; 86: 402a
28. Pettengell R., Morgenstern G. R., Woll P. J., Chang J., Rowland M., Young R., Radford J. A., Scarffe J. H., Testa N. G., Crowther D. Peripheral blood progenitor cell transplantation in lymphoma and leukemia using a single apheresis. Blood 1993; 82: 3770 – 3778
29. Passos-Coelho J. L., Braine H. G., Wright S. K., Davis J. M., Schepers K. G., Huelskamp A-M., Clarke B., Noga S. J., Kennedy M. J. Large volume leukapheresis using regional citrate anticoagulant to collect peripheral blood progenitor cells. J. Hematother. 1995; 4: 11 – 19
30. To L. B., Haylock D. N., Dowse T., Simmons P. J., Trimboli S., Ashman L. K., Juttner C. A. A comparative study of the phenotype and proliferative capacity of peripheral blood CD34+ cells mobilized by 4 different protocols and those of steady-phase PB and bone marrow CD34+ cells. Blood 1994; 84: 2930 – 2939
31. Moss T. J., Cairo M., Sanlana V. M., Weinthal J., Hurvitz C., Bostrom M. Clonogenic circulating BM cells: Implications regarding peripheral stem cell transplantation. Blood 1994; 83: 3085 – 3089
32. Shpall E. J., Jones R. Release of tumor cells from bone marrow. Blood 1994; 83: 623 – 625
33. Brugger W., Bross K. J., Glatt M., Weber F., Mertelsmann L., Kanz L. Mobilization of tumor cells and hematopoietic progenitor cells into peripheral blood of patients with solid tumors. Blood 1994; 83: 636 – 640
34. Pilarksi L. M., Jensen G. S. Monoclonal circulating B cells in multiple myeloma. Hematol. Oncol. Clin. N. Am. 1992; 6: 297 – 322
35. Gazitt Y., Tian E., Barlogie B., Reading C., Vesole D., Jagannath S., Schnell J., Hoffman R., Tricot G. Differential mobilization of myeloma cells and normal hematopoietic stem cells after treatment with cyclophosphamide and GM-CSF. Blood 1996; 87: 805 – 811
36. Passos-Coelho J. L., Ross A. A., Moss T. J., Davis M., Huelskamp A-M., Noga S. J., Davidson N. E., Kennedy J. Absence of breast cancer cells in a single-day peripheral blood cell collection after priming with cyclophosphamide and GM-CSF. Blood 1995; 85: 1138 – 1143
37. Bast R. C., Defabritis P., Lipton J., Gelber R., Maver C., Nadler L., Sallan S., Ritz J. Cancer Res. 1985; 45: 499 – 506
38. Gribben J. G., Freedman A. S., Neuberg D., Roy D. C., Blake K. W., Woo S. D., Grossbard M. L., Rabinowe S. N., Coral F., Freeman G. J., Ritz J., Nadler L. M. Immunologic purging of marrow assessed by PCR before autologous bone marrow transplantation for B-cell lymphoma. N. Eng. J. Med. 1991; 325: 1525 – 1533
39. Vitetta E. From the basic science of B-cells to biologic missiles at the bedside. J. Immunol. 1994; 153: 1407 – 1420
40. Shpall E. J., Bast R. C., Joines W. T., Jones R. B., Anderson I., Johnston C., Egglestone S., Tepperberg M., Edwards S., Peters W. P. Immunomagnetic purging of breast cancer from bone marrow for autologous transplantation. Bone Marrow Transplant. 1991; 7: 145 – 151
41. Anderson K. C., Anderson J., Soiffer R., Freedman A. S., Rabinowe S. N., Robertson M. J., Spector N., Blake K., Murray C., Freeman A., Coral F., Marcus K. C., Mauch P., Nadler L., Ritz J. Monoclonal antibody purged bone marrow transplantation therapy for multiple myeloma. Blood, 82: 2568 – 2577
42. Broun E. R., Traycott C. M., Graves V., Sledge G. W., Mills B., Oldham F., Srour E. F. A comparison of engraftment following high dose chemotherapy with autologous bone marrow transplantation with either full bone maroww or CD34+ cells isolated with the Baxter Isolex 500. Expt. Hematol. 1994; 22: 775
43. Heimfeld S., Fogartz B., McGuire K., Williams S., Berensen R. J. Peripheral blood stem cell mobilization after stem cell factor or G-CSF treatment. Rapid enrichment for stem cells and progenitor cells using Separate immunoaffinity separation system. J. Clin. Oncol. 1988; 6: 1368 – 1372
44. Shpall E. J., Jones R. B., Berman S. I., Franklin W. A., Archer E. J., Curiel T., Bitter M., Claman H. N., Stemmer S. M., Purdy M., Myers S. E., Hami L., Taffs S., Heimfeld S., Hallagan J., Berenson R. J. Transplantation of enriched CD34+ cells autologous marrow into breast cancer patients following high dose chemotherapy: Influence of CD34+ positive peripheral blood progenitors and growth factors on engraftment. J. Clin. Oncol. 1994; 12: 28 – 36
45. Brugger W., Henschler R., Heimfeld S., Berenson R. J., Mertelsman R., Kranz L. Positively selected autologous blood CD34+ cells and unseparated peripheral blood progenitor cells mediate identical hematopoietic engraftment after high-dose VP16, ifosfamide, carboplatin, and epirubicin. Blood 1994; 84: 1421 – 1426
46. Lebkowski J. S., Schain L., Harvey M., Mowicki B., Okama T. B., Sniecinki I. Rapid isolation of CD34+ cells from peripheral blood of autologous transplant patients. Blood 1992; 80: 527a
47. Cross N. C., Feng L., Chase A., Bungey J., Hughes T. P., Goldman J. M. Competitive PCR reaction to estimate the number of bcr-abl transcripts in CML patients after bone marrow transplantation. Blood 1993; 82: 1929 – 1936
48. Brisco M. J., Tan L. W., Orsborn A. M., Morley A. A. Development of a highly sensitive assay, based on the polymerase chain reaction, for rare B-lymphocyte clones in a polyclonal population. Br. J. Haematol. 1990; 75: 163 – 167
49. Billadeau D., Blackstadt M., Greipp P., Kyle R. A., Oken M. M., Kay N., Van Ness B. Analysis of B-lymphoid malignancies using allele-specific polymerase chain reaction: a technique for sequential quantitation of residual disease. Blood 1991; 78: 3021 – 3029
50. Neale G. A. M., Menarguez J., Kitchingman G. R., Fitzgerald T. J., Koehler M., Mirro J., Goorha R. Detection of minimal residual disease in T-cell acute lyphoblastic leukemia using PCR predicts impeding relapse. Blood 1991; 78: 793 – 800
51. Campana D., Pui C-H. Detection of minimal residual disease in acute leukemia: Methodologic advances and clinical significance. Blood 1995; 85: 1416 – 1434
52. Vesole D., Barlogie B., Jagannath S., Cheson B., Tricot G., Crowley J. High dose therapy for multiple myeloma: Improved prognosis with better supportive care and double transplant. Blood 1994; 84: 950 – 956
53. Tricot G., Jagannath S., Vesole D., Nelson J., Tindle S., Miller L., Cheson B., Crowley J., Barlogie B. Peripheral blood stem cell transplants for multiple myeloma: Identification of favorable variables for rapid engraftment in 225 patients. Blood 1995; 85: 588 – 596
54. Holden T. J., Geller R. B., Farhi D. C., Holland K., Stempora L. L., Phillips C. N., Bray R. A. Characterization of Thy-1 expression in acute leukemia. Blood 1995; 86: 60 – 65
55. Kohler G., Brugger W., Schaefer H. E., Kanz L. Expression of the CD34+ antigen on tumor cells. Blood 1994; 84: 497a
56. Wessman M., Schnell J., Van Den Berg D., Kshirsaga B., Sriti Z., Reading C. Fluorescent detection of metastatic breast cancer cells in bone marrow and mobilized peripheral blood by immunofluorescence and by high speed flow-cytometry. Blood 1995; 86: 919a
57. Belch A. R., Bergsagel P. L., Lansdorp P., Pilarski L. M. CD34+ B-cells in blood of patients with multiple myeloma express clonogenic IgH sequences. Blood 1994; 84: 385a
58. Epstein J., Xiao H., He X. Y. Marker of multiple hematopoietic lineage in multiple myeloma. New Engl. J. Med. 1990; 322: 664 – 668
59. Srour E. F., Brandt J. E., Briddell R. A., Leemhuis T., Van Besien K., Hoffman R. Human CD34+ HLA-DR bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis. Blood Cells 1991; 17: 287 – 295
60. Uchida N., Aguila H. L., Fleming W. H., Jerabek L., Weissman I. L. Rapid and sustained hematopoietic recovery in lethally irradiated mice transplanted with purified Thy-1.110 Lin Sca-1+ hematopoietic stem cells. Blood 1994; 83: 3758 – 3779
61. Udomsakdi C., Lansdorp P. M., Hogge D. E., Reid D. S., Eaves A. C., Eaves C. J. Characterization of primitive hematopoietic cells in normal human peripheral blood. Blood 1992; 80: 2513 – 2521
62. Baum C. M., Weissman I. L., Tsukamoto A. S., Buckle A-M., Peault B. Isolation of a candidate human hematopoietic stem-cell population. Proc. Natl. Acad. Sci. USA 1992; 89: 2804 – 2808
63. Craig W., Kay R., Cutler R. L., Lansdorp P. M. Expression of Thy-1 on human hematopoietic progenitor cells. J. Exp. Med. 1993; 177: 1331 – 1338
64. Murray L., Chen B., Galy A., Chen S., Tushinski R., Uchida N., Negrin R., Tricot G., Jagannath S., Vesole D., Barlogie B., Hoffman R., Tsukamoto A. Enrichment of human hematopoietic stem cell activity in the CD34+ Thy-1+Lin subpopulation from mobilized peripheral blood. Blood 1995; 85: 368 – 378
65. Negrin R. S., Kusnierz-Glaz C. R., Still B. J., Schriber J. R., Chao N. J., Long G. W., Hoyle C., Hu W. W., Horning S. J., Brown B. W., Blume K. G., Strober S. Transplantation of enriched and purged peripheral blood progenitor cells from a single apheresis product in patients with non-Hodgkin's lymphoma. Blood 1995; 85: 3334 – 3341