The effect of pioglitazone on glucose metabolism and insulin uptake in the perfused liver and hindquarter of high-fructose-fed rats

Metabolism: Clinical and Experimental

Volumn 47, Issue 9, 1998, Pages 1152-1155

  Ikeda, Tadasu ^a   Fujiyama, Katsumi ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FRUCTOSE; GLUCOSE; INSULIN; PIOGLITAZONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DIETARY INTAKE; DRUG MIXTURE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; INSULIN BLOOD LEVEL; LIVER PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031754460     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(98)90292-X     Document Type: Article

References (24)

1. Ikeda H, Taketomi S, Sugiyama Y, et al: Effects of pioglitazone on glucose and lipid metabolism in normal and insulin resistant animals. Arzneim Forsch Drug Res 40:156-162, 1990
2. Hoffman CA, Lorenz K, Colca JR: Glucose transport deficiency in diabetic animals is corrected by treatment with the oral antihyperglycemic agent pioglitazone. Endocrinology 129:1915-1925, 1991
3. Sugiyama Y, Shimura Y, Ikeda H: Effects of pioglitazone on hepatic and peripheral insulin resistance in Wistar fatty rats. Arzneim Forsch Drug Res 40:436-440, 1990
4. Oakes ND, Kennedy DC, Jenkins AB, et al: A new antidiabetic agent, BRL 49635, reduces lipid availability and improves insulin action and glucoregulation in rats. Diabetes 43:1203-1210, 1994
5. Lee MK, Miles PDG, Khoursheed M, et al: Metabolic effects of troglitazone on fructose-induced insulin resistance in the rat. Diabetes 43:1435-1439, 1994
6. Iwamoto Y, Kuzuya T, Matsuda A, et al: Effect of new oral antidiabetic agent CS-045 on glucose tolerance and insulin secretion in patients with NIDDM. Diabetes Care 14:1083-1086, 1991
7. Suter SL, Nolan JJ, Wallace E, et al: Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care 15:193-203, 1992
8. Nolan JJ, Ludvik B, Beerdsen P, et al: Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med 331:1188-1193, 1994
9. Ikeda T, Mokuda O, Tominaga M, et al: Glucose intolerance in thyrotoxic rats: Role of insulin, glucagon, and epinephrine. Am J Physiol 255:E843-E849, 1988
10. Sugano T, Suda K, Shimada M, et al: Biochemical and ultrastructural evaluation of isolated rat liver systems perfused with a hemoglobin-free medium. J Biochem 83:995-1007, 1978
11. Ikeda T, Ishimura M, Terasawa H, et al: Uptake of ketone bodies in perfused hindquarter and kidney of starved, thyrotoxic, and diabetic rats. Proc Soc Exp Biol Med 203:55-59, 1993
12. Ikeda T, Ohtani I, Fujiyama K, et al: Uptake of β-hydroxybutyrate in perfused hindquarter of starved and diabetic rats. Metabolism 40:1287-1291, 1991
13. Ruderman NB, Houghton CRS, Hems R: Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism. Biochem J 124:639-651, 1971
14. Hugget A, Nixon DA: Use of glucose oxidase, peroxidase and D-dionisidine in determination of blood and urinary glucose. Lancet 2:368-370, 1957
15. Tobey TA, Mondon CE, Zavaroni I, et al: Mechanism of insulin resistance in fructose-fed rats. Metabolism 31:608-612, 1982
16. Beck-Nielsen H, Pedersen O, Sorensen NS: Effects of diet on the cellular insulin binding and the insulin sensitivity in young healthy subjects. Diabetologia 15:289-296, 1978
17. Blumenthal MD, Abrahams S, Chaikoff IL: Dietary control of liver glucokinase activity in the normal rat. Arch Biochem Biophys 104:215-224, 1964
18. Tuovinen CGR, Bender AE: Some metabolic effects of prolonged feeding of starch, sucrose, fructose and carbohydrate-free diet in the rat. Nutr Metab 19:161-172, 1975
19. Inoue I, Takahashi K, Katayama S, et al: Effect of troglitazone (CS-045) and bezafibrate on glucose tolerance, liver glycogen synthase activity, and β-oxidation in fructose-fed rats. Metabolism 44:1626-1630, 1995
20. Okuno A, Ikeda K, Shiota M, et al: Acute effect of troglitazone on glucose metabolism in the absence or presence of insulin in perfused rat hindlimb. Metabolism 46:716-721, 1997
21. Randle PJ, Kerbey AL, Espinal J: Mechanisms decreasing glucose oxidation in diabetes and starvation: Role of lipid fuels and hormones. Diabetes Metab Rev 4:623-638, 1988
22. Wolfe BM, Klein S, Peters EJ, et al: Effect of elevated free fatty acids on glucose oxidation in normal humans. Metabolism 37:323-329, 1988
23. Kelly DE, Mokan M, Simoneau J, et al: Interaction between glucose and free fatty acid metabolism in human skeletal muscle. J Clin Invest 92:91-98, 1993
24. Hayakawa T, Shiraki T, Morimoto T, et al: Pioglitazone improves insulin signaling defects in skeletal muscle from Wistar fatty (fa/fa) rats. Biochem Biophys Res Commun 223:439-444, 1996