Regional differences within the rat ventral tegmental area for muscimol self-infusions

Pharmacology Biochemistry and Behavior

Volumn 61, Issue 1, 1998, Pages 87-92

  Ikemoto, Satoshi ^a,c   Murphy, James M ^b   McBride, William J ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PURDUE UNIVERSITY   (United States)

^c LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

Caudal linear nucleus; GABA(A) receptors; Intracranial self administration; Muscimol; Reinforcement; Ventral tegmental area

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; MUSCIMOL; PICROTOXIN;

ANIMAL EXPERIMENT; ARTICLE; BRAIN REGION; CONTROLLED STUDY; FEMALE; INTRACEREBRAL DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; SELF INJECTION; VENTRAL TEGMENTUM;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FEMALE; GABA AGONISTS; GABA ANTAGONISTS; MUSCIMOL; PICROTOXIN; RATS; RATS, WISTAR; RECEPTORS, GABA-A; SELF ADMINISTRATION; VENTRAL TEGMENTAL AREA;

EID: 0031753073     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(98)00086-0     Document Type: Article

References (21)

1. Arnt, J.; Scheel-Krüger, J.: GABA in the ventral tegmental area: Differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists. Life Sci. 25:1351-1360;1979.
2. Bozarth, M. A.; Wise, R. A.: Electrolytic microinfusion transducer system: An alternative method of intracranial drug application. J. Neurosci. Methods 2:273-275; 1980.
3. Criswell, H. E.: A simple chronic microinjection system for use with chemitrodes. Pharmacol. Biochem. Behav. 6:237-238; 1977.
4. 2 dopaminergic mechanisms. Psychopharmacology (Berlin) 130:85-90; 1997.
5. Goeders, N. E.; Smith, J. E.: Intracranial self-administration methodologies. Neurosci. Biobehav. Rev. 11:319-329; 1987.
6. 2 receptors in the nucleus accumbens in mediating reward. J. Neurosci. 17:8580-8587; 1997.
7. A receptor blockade in the anterior ventral tegmental area increases extracellular levels of dopamine in the nucleus accumbens of rats. J. Neurochem. 69:137-143; 1997.
8. A antagonists directly into the ventral tegmental area and adjacent regions. Behav. Neurosci. 111:369-380; 1997.
9. Ikemoto, S.; Panksepp, J.: Dissociations between appetitive and consummatory responses by pharmacological manipulations of reward-relevant brain regions. Behav. Neurosci. 110:331-345; 1996.
10. Kalivas, P. W.: Neurotransmitter regulation of dopamine neurons in the ventral tegmental area. Brain Res. Rev. 18:75-113; 1993.
11. Kalivas, P. W.; Duffy, P.; Eberhardt, H.: Modulation of A10 dopamine neurons by gamma-aminobutyric acid agonists. J. Pharmacol. Exp. Ther. 253:858-866; 1990.
12. Klitenick, M. A.; DeWitte, P.; Kalivas, P. W.: Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: An in vivo microdialysis study. J. Neurosci. 12:2623-2632; 1992.
13. Koob, G. F.; Weiss, F.: Pharmacology of drug self-administration. Alcohol 7:193-197; 1990.
14. Mogenson, G. J.; Wu, M.; Jones, D. L.: Locomotor activity elicited by injections of picrotoxin into the ventral tegmental area is attenuated by injections of GABA into the global pallidus. Brain Res. 191:569-571; 1980.
15. Mogenson, G. J.; Wu, M.; Manchanda, S. K.: Locomotor activity initiated by microinjection of picrotoxin into the ventral tegmental area. Brain Res. 161:311-319; 1979.
16. Paxinos, G.; Watson, C.: The rat brain in stereotaxic coordinates, 2nd ed. San Diego; Academic Press Inc.; 1986.
17. Phillips, G. D.; Robbins, T. W.; Everitt, B. J.: Bilateral intra-accumbens self-administration of d-amphetamine: Antagonism with intra-accumbens SCH-23390 and sulpiride. Psychopharmacology (Berlin) 114:477-485; 1994.
18. Stinus, L.; Herman, J. P.; Le Moal, M.: GABAergic mechanisms within the ventral tegmental area: Involvement of dopaminergic (A10) and nondopaminergic neurons. Psychopharmacology (Berlin) 77:186-192; 1982.
19. Tanner, T.: GABA-induced locomotor activity in the rat, after bilateral injection into the ventral tegmental area. Neuropharmacology 18:441-446; 1979.
20. Westerink, B. H. C.; Kwint, H.-F.; deVries, J. B.: Neuropharmacology of mesolimbic dopamine neurons: Dual-probe microdialysis study in the ventral tegmental area and nucleus accumbens of the rat brain. J. Neurosci. 16:2605-2611; 1996.
21. Wirtshafter, D.; Klitenick, M. A.: Comparative studies of locomotor behavior following microinjections of muscimol into various sites in the paramedian tegmentum. Pharmacol. Biochem. Behav. 32:625-628; 1989.