-
1
-
-
0028278931
-
The insulin receptor: Structure, function, and signaling
-
Lee, J., and Pilch, P. F. (1994) The insulin receptor: structure, function, and signaling. Am. J. Physiol. 266, C319-C334
-
(1994)
Am. J. Physiol.
, vol.266
-
-
Lee, J.1
Pilch, P.F.2
-
2
-
-
0028818886
-
How do protein kinases discriminate between serine/threonine and tyrosine? Structural insights from the insulin receptor protein-tyrosine kinase
-
Taylor, S. S., Radzio-Andzelm, E., and Hunter, T. (1995) How do protein kinases discriminate between serine/threonine and tyrosine? Structural insights from the insulin receptor protein-tyrosine kinase. FASEB J. 9, 1255-1260
-
(1995)
FASEB J.
, vol.9
, pp. 1255-1260
-
-
Taylor, S.S.1
Radzio-Andzelm, E.2
Hunter, T.3
-
3
-
-
0345476725
-
Phosphorylation activates the insulin receptor tyrosine protein kinase
-
Rosen, O. M. Herrera, R., Olowe, Y., Petruzzelli, L. M., and Cobb, M. H. (1983) Phosphorylation activates the insulin receptor tyrosine protein kinase. Proc. Natl. Acad. Sci. USA 80, 3237-3240
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 3237-3240
-
-
Rosen, O.M.1
Herrera, R.2
Olowe, Y.3
Petruzzelli, L.M.4
Cobb, M.H.5
-
4
-
-
0028582185
-
Crystal structure of the tyrosine kinase domain of the human insulin receptor
-
Hubbard, S. R., Wie, I., Ellis, L., and Hendrickson, W. A. (1994) Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature (London) 372, 746-754
-
(1994)
Nature (London)
, vol.372
, pp. 746-754
-
-
Hubbard, S.R.1
Wie, I.2
Ellis, L.3
Hendrickson, W.A.4
-
5
-
-
0030766163
-
Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog
-
Hubbard, S. R. (1997) Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog. EMBO J. 16, 5572-5581
-
(1997)
EMBO J.
, vol.16
, pp. 5572-5581
-
-
Hubbard, S.R.1
-
6
-
-
0017261573
-
Differential effects of sulfhydryl reagents on activation and deactivation of the fat cell hexose transport system
-
Czech, M. P. (1976) Differential effects of sulfhydryl reagents on activation and deactivation of the fat cell hexose transport system. J. Biol. Ckem. 251, 1164-1170
-
(1976)
J. Biol. Ckem.
, vol.251
, pp. 1164-1170
-
-
Czech, M.P.1
-
7
-
-
0020037168
-
Similarities between insulin, hydrogen peroxide, concanavalin A, and anti-insulin receptor antibody stimulated glucose transport: Increase in the number of transport sites
-
Ludvigsen, C., and Jarett, L. (1982) Similarities between insulin, hydrogen peroxide, concanavalin A, and anti-insulin receptor antibody stimulated glucose transport: increase in the number of transport sites. Metabolism 31, 284-287
-
(1982)
Metabolism
, vol.31
, pp. 284-287
-
-
Ludvigsen, C.1
Jarett, L.2
-
8
-
-
0016284089
-
Evidence for the involvement of sulfhydryl oxidation in the regulation of fat cell hexose transport by insulin
-
Czech, M. P., Lawrence, J. C., Jr., and Lynn, W. S. (1974) Evidence for the involvement of sulfhydryl oxidation in the regulation of fat cell hexose transport by insulin. Proc. Natl. Acad. Sci. USA 71, 4173-4177
-
(1974)
Proc. Natl. Acad. Sci. USA
, vol.71
, pp. 4173-4177
-
-
Czech, M.P.1
Lawrence Jr., J.C.2
Lynn, W.S.3
-
9
-
-
0023655201
-
Stimulation of insulin-like growth factor II receptor binding and insulin receptor kinase activity in rat adipocytes
-
Kadota, S., Fantus, I. G., Deragon, G., Guyda, H. J., and Posner, B. I. (1987) Stimulation of insulin-like growth factor II receptor binding and insulin receptor kinase activity in rat adipocytes. J. Biol. Chem. 262, 8252-8256
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 8252-8256
-
-
Kadota, S.1
Fantus, I.G.2
Deragon, G.3
Guyda, H.J.4
Posner, B.I.5
-
10
-
-
0023442337
-
Role of insulin receptor phosphorylation in the insulinomimetic effects of hydrogen peroxide
-
Hayes, G. R., and Lockwood, D. H. (1987) Role of insulin receptor phosphorylation in the insulinomimetic effects of hydrogen peroxide. Proc. Natl. Acad. Sci. USA 84, 8115-8119
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 8115-8119
-
-
Hayes, G.R.1
Lockwood, D.H.2
-
11
-
-
0023931255
-
Hydrogen peroxide stimulates tyrosine phosphorylation of the insulin receptor and its tyrosine kinase activity in intact cells
-
Koshio, O., Akanuma, Y., and Kasuga, M. (1988) Hydrogen peroxide stimulates tyrosine phosphorylation of the insulin receptor and its tyrosine kinase activity in intact cells. Biochem. J. 250, 95-101.
-
(1988)
Biochem. J.
, vol.250
, pp. 95-101
-
-
Koshio, O.1
Akanuma, Y.2
Kasuga, M.3
-
12
-
-
0025193521
-
2 and vanadate stimulate protein tyrosine phosphorylation in intact cells
-
2 and vanadate stimulate protein tyrosine phosphorylation in intact cells. J. Biol. Chem. 265, 2896-2902
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 2896-2902
-
-
Heffetz, D.1
Bushkin, I.2
Dror, R.3
Zick, Y.4
-
13
-
-
0021166181
-
A novel mechanism for the insulin-like effect of vanadate on glycogen synthase in rat adipocytes
-
Tamara, S., Brown, T. A., Whipple, J. H., Fujita-Yamaguchi, Y., Dubler, R. E., Cheng, K., and Larner, J. (1984) A novel mechanism for the insulin-like effect of vanadate on glycogen synthase in rat adipocytes. J. Biol. Chem. 259, 6650-6658
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 6650-6658
-
-
Tamara, S.1
Brown, T.A.2
Whipple, J.H.3
Fujita-Yamaguchi, Y.4
Dubler, R.E.5
Cheng, K.6
Larner, J.7
-
14
-
-
0024416087
-
Pervanadate (peroxide(s) of vanadate) mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase
-
Fantus, G., Kadota, S., Deragon, G., Foster, B., and Posner, B. I. (1989) Pervanadate (peroxide(s) of vanadate) mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase. Biochemistry 28, 8864-8871
-
(1989)
Biochemistry
, vol.28
, pp. 8864-8871
-
-
Fantus, G.1
Kadota, S.2
Deragon, G.3
Foster, B.4
Posner, B.I.5
-
15
-
-
0023192743
-
Differential sensitivity of the insulin-receptor kinase to thiol and oxidizing agents in the absence and presence of insulin
-
Wilden, P. A., and Pessin, J. E. (1987) Differential sensitivity of the insulin-receptor kinase to thiol and oxidizing agents in the absence and presence of insulin. Biochem. J. 245, 325-331
-
(1987)
Biochem. J.
, vol.245
, pp. 325-331
-
-
Wilden, P.A.1
Pessin, J.E.2
-
16
-
-
0029038858
-
Thiol-specific biotinylation of the insulin receptor in permeabilized cells enhances receptor function
-
Bernier, M., Nadiv, O., and Kole, H. K. (1995) Thiol-specific biotinylation of the insulin receptor in permeabilized cells enhances receptor function. Biochemistry 34, 8357-8364
-
(1995)
Biochemistry
, vol.34
, pp. 8357-8364
-
-
Bernier, M.1
Nadiv, O.2
Kole, H.K.3
-
17
-
-
0027173479
-
Sulphydryl agents modulate insulin- and epidermal growth factor (EGF) receptor kinase via reaction with intracellular receptor domains: Differential effects on basal versus activated receptors
-
Clark, S., and Konstantopoulos, N. (1993) Sulphydryl agents modulate insulin- and epidermal growth factor (EGF) receptor kinase via reaction with intracellular receptor domains: differential effects on basal versus activated receptors. Biochem. J. 292, 217-223
-
(1993)
Biochem. J.
, vol.292
, pp. 217-223
-
-
Clark, S.1
Konstantopoulos, N.2
-
18
-
-
0028941088
-
Mutagenic structure/function analysis of the cytoplasmic cysteines of the insulin receptor
-
Macaulay, S. L., Polites, M., Frenkel, M. J, Hewish, D. R., and Ward, C. W. (1995) Mutagenic structure/function analysis of the cytoplasmic cysteines of the insulin receptor. Biochem. J. 306, 811-820
-
(1995)
Biochem. J.
, vol.306
, pp. 811-820
-
-
Macaulay, S.L.1
Polites, M.2
Frenkel, M.J.3
Hewish, D.R.4
Ward, C.W.5
-
19
-
-
0025753381
-
Insulin sensitivity and insulin clearance in human immunodeficiency virus-infected men
-
Hommes, M. J. T., Romijn, J. A., Endert, E., Schattetikerk, J. K. M. E., and Sauerwein, H. P. (1991) Insulin sensitivity and insulin clearance in human immunodeficiency virus-infected men. Metabolism 40, 651-656
-
(1991)
Metabolism
, vol.40
, pp. 651-656
-
-
Hommes, M.J.T.1
Romijn, J.A.2
Endert, E.3
Schattetikerk, J.K.M.E.4
Sauerwein, H.P.5
-
20
-
-
0030457787
-
Elevated hepatic γ-glutamylcysteine synthetase activity and abnormal sulfate levels in liver and muscle tissue may explain cysteine and glutathione levels in SIV-infected rhesus macaques
-
Gross, A., Hack, V., Stahl-Hennig, C., and Dröge, W. (1996) Elevated hepatic γ-glutamylcysteine synthetase activity and abnormal sulfate levels in liver and muscle tissue may explain cysteine and glutathione levels in SIV-infected rhesus macaques. AIDS Res. Hum. Retrovir. 12, 1639-1641
-
(1996)
AIDS Res. Hum. Retrovir.
, vol.12
, pp. 1639-1641
-
-
Gross, A.1
Hack, V.2
Stahl-Hennig, C.3
Dröge, W.4
-
21
-
-
0026713818
-
Cytotoxic activity of tumor necrosis factor is mediated by an early damage of mitochondrial functions. Evidences for the involvement of milochondrial radical generation
-
Schulze-Osthoff, K., Bakker, A. C., Vanhaesebroeck, B., Beyaert, R., Jacobs, W., and Fiers, W. (1992) Cytotoxic activity of tumor necrosis factor is mediated by an early damage of mitochondrial functions. Evidences for the involvement of milochondrial radical generation. J. Biol. Chem. 267, 5317-5323
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 5317-5323
-
-
Schulze-Osthoff, K.1
Bakker, A.C.2
Vanhaesebroeck, B.3
Beyaert, R.4
Jacobs, W.5
Fiers, W.6
-
22
-
-
0345243669
-
Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cell
-
Ebina, Y., Edery, M., Ellis, L., Standring, D., Beaudoin, J., Roth, R. A., and Rutter, W. J. (1985) Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cell. Proc. Natl. Acad. Sci. USA 82, 8014-8018
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 8014-8018
-
-
Ebina, Y.1
Edery, M.2
Ellis, L.3
Standring, D.4
Beaudoin, J.5
Roth, R.A.6
Rutter, W.J.7
-
23
-
-
0021924895
-
The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling
-
Ebina, Y., Ellis, L., Jarnagin, K., Edery, M., Graf, L., Clauser, E., Ou, J.-H., Masiarz, F., kann, Y. W., Goldfine, I. D., Roth, R. A., and Rutter, W. (1985) The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling. Cell 40, 747-758
-
(1985)
Cell
, vol.40
, pp. 747-758
-
-
Ebina, Y.1
Ellis, L.2
Jarnagin, K.3
Edery, M.4
Graf, L.5
Clauser, E.6
Ou, J.-H.7
Masiarz, F.8
Kann, Y.W.9
Goldfine, I.D.10
Roth, R.A.11
Rutter, W.12
-
24
-
-
0024595926
-
Low concentrations of acid soluble thiol (cysteine) in the blood plasma of HIV-1 infected patients
-
Eck, H.-P., Gmünder, H., Hartmann, M., Peizoldt, D., Daniel, V., and Dröge, W. (1989) Low concentrations of acid soluble thiol (cysteine) in the blood plasma of HIV-1 infected patients. Biol. Chem. Hoppe-Seyler 370, 101-108
-
(1989)
Biol. Chem. Hoppe-Seyler
, vol.370
, pp. 101-108
-
-
Eck, H.-P.1
Gmünder, H.2
Hartmann, M.3
Peizoldt, D.4
Daniel, V.5
Dröge, W.6
-
25
-
-
0018666729
-
Potent and specific inhibitor of glutathione synthesis by buthionine sulfoximine (S-h-butylhomocysteine sulfoximine)
-
Griffith, O., and Meister A. (1979) Potent and specific inhibitor of glutathione synthesis by buthionine sulfoximine (S-h-butylhomocysteine sulfoximine). J. Biol. Chem. 254, 7558-7560
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 7558-7560
-
-
Griffith, O.1
Meister, A.2
-
26
-
-
0017687764
-
Severe generalized glutathione reductase deficiency after antitumor chemotherapy with BCNU
-
Frischer, H., and Ahmad T. (1977) Severe generalized glutathione reductase deficiency after antitumor chemotherapy with BCNU. J. Lab. Clin. Med. 89, 1080-1082
-
(1977)
J. Lab. Clin. Med.
, vol.89
, pp. 1080-1082
-
-
Frischer, H.1
Ahmad, T.2
-
27
-
-
0023839663
-
Inhibition of glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea
-
Karplus, P. A., Krauth-Siegel, R. L., Schirmer, R. H., and Schulz, G. E. (1988) Inhibition of glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea. Eur. J. Biochem. 171, 193-198
-
(1988)
Eur. J. Biochem.
, vol.171
, pp. 193-198
-
-
Karplus, P.A.1
Krauth-Siegel, R.L.2
Schirmer, R.H.3
Schulz, G.E.4
-
28
-
-
0017613512
-
A simplification of the protein assay method of Lowry et al. which is more generally applicable
-
Peterson, G. L. (1977) A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem. 83, 346-356
-
(1977)
Anal. Biochem.
, vol.83
, pp. 346-356
-
-
Peterson, G.L.1
-
29
-
-
0030764621
-
phox during human neutrophil activation
-
phox during human neutrophil activation. J. Biol. Chem. 272, 17204-17208
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17204-17208
-
-
El Benna, J.1
Dang, P.M.-C.2
Gaudry, M.3
Fay, M.4
Morel, F.5
Hakim, J.6
Gougerot-Pocidalo, M.-A.7
-
30
-
-
0025998840
-
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
-
Boyle, W. J., van der Geer, P., and Hunter, T. (1991) Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol. 201, 110-149
-
(1991)
Methods Enzymol.
, vol.201
, pp. 110-149
-
-
Boyle, W.J.1
Van der Geer, P.2
Hunter, T.3
-
31
-
-
0027277107
-
Insulin stimulates serine and tyrosine phosphorylation in the juxtamembrane region of the insulin receptor
-
Feener, E. P., Backer, J. M., King, G. L., Wilden, P. A., and Sun, X. J. (1993) Insulin stimulates serine and tyrosine phosphorylation in the juxtamembrane region of the insulin receptor. J. Biol. Chem. 268, 11256-11264
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 11256-11264
-
-
Feener, E.P.1
Backer, J.M.2
King, G.L.3
Wilden, P.A.4
Sun, X.J.5
-
32
-
-
0030057750
-
Protein S-thiolation and dethiolation during the respiratory burst in human monocytes. A reversible post-translational modification with potential for buffering the effects of oxidant stress
-
Seres, T., Ravichandran, V., Moriguchi, T., Rokutan, K., Thomas, J. A., and Johnston, R. B., Jr. (1996) Protein S-thiolation and dethiolation during the respiratory burst in human monocytes. A reversible post-translational modification with potential for buffering the effects of oxidant stress. J. Immunol. 156, 1973-1980
-
(1996)
J. Immunol.
, vol.156
, pp. 1973-1980
-
-
Seres, T.1
Ravichandran, V.2
Moriguchi, T.3
Rokutan, K.4
Thomas, J.A.5
Johnston Jr., R.B.6
-
33
-
-
0026502692
-
Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation
-
Carpentier, J.-L., Paccaud, J.-P., Gorden, P., Rutter, W. J., and Orci, L. (1992) Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation. Proc. Natl. Acad. Sci. USA 89, 162-166
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 162-166
-
-
Carpentier, J.-L.1
Paccaud, J.-P.2
Gorden, P.3
Rutter, W.J.4
Orci, L.5
-
34
-
-
0030841111
-
Effects of sulfhydryl modification reagents on the kinase activity of the epidermal growth factor receptor
-
Woltjer, R. L., and Staros, J. V. (1997) Effects of sulfhydryl modification reagents on the kinase activity of the epidermal growth factor receptor. Biochemistry 36, 9911-9916
-
(1997)
Biochemistry
, vol.36
, pp. 9911-9916
-
-
Woltjer, R.L.1
Staros, J.V.2
-
35
-
-
0025825989
-
Redox regulation of a protein tyrosine kinase in the endoplasmic reticulum
-
Bauskin, A. R., Alkalay, I., and Ben-Neriah, Y. (1991) Redox regulation of a protein tyrosine kinase in the endoplasmic reticulum. Cell 66, 685-696
-
(1991)
Cell
, vol.66
, pp. 685-696
-
-
Bauskin, A.R.1
Alkalay, I.2
Ben-Neriah, Y.3
|