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Volumn 37, Issue 2, 1998, Pages 112-122

The treatment of heart failure: The role of neurohumoral activation

Author keywords

Angiotensin converting enzyme inhibitors (ACEI); Beta receptor blockers; Digitalis; Exercise training; Renin angiotensin system; Sympathetic nervous system (SNS)

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIGITALIS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; NORADRENALIN; VASOPRESSIN;

EID: 0031748195     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.37.112     Document Type: Review
Times cited : (50)

References (68)
  • 1
    • 0027167633 scopus 로고
    • Plasma norepinephrine, Plasma renin activity, and congestive heart failure: Relations to survival and the effects of therapy in V-Heft II
    • Francis GS, Cohn JN, Johnson G, Rector TS, Goldman S, Simon A. Plasma norepinephrine, Plasma renin activity, and congestive heart failure: Relations to survival and the effects of therapy in V-Heft II. Circulation 87: V140, 1993.
    • (1993) Circulation , vol.87
    • Francis, G.S.1    Cohn, J.N.2    Johnson, G.3    Rector, T.S.4    Goldman, S.5    Simon, A.6
  • 2
    • 0028966468 scopus 로고
    • A functional role for endogenous atrial natriuretic peptide in a canine model of early left ventricular dysfunction
    • Stevens TL, Burnett JC, Jr, Kinoshita M, Matsuda Y, Redfield MM. A functional role for endogenous atrial natriuretic peptide in a canine model of early left ventricular dysfunction. J Clin Invest 95: 1101, 1995.
    • (1995) J Clin Invest , vol.95 , pp. 1101
    • Stevens, T.L.1    Burnett Jr., J.C.2    Kinoshita, M.3    Matsuda, Y.4    Redfield, M.M.5
  • 3
    • 0030069614 scopus 로고    scopus 로고
    • Role of spectral measures of heart rate variability as markers of disease progression in patients with chronic congestive heart failure not treated with angiotensin-converting enzyme inhibitors
    • Panina G, Knot UN, Nunziata E, Cody RJ, Binkley PF. Role of spectral measures of heart rate variability as markers of disease progression in patients with chronic congestive heart failure not treated with angiotensin-converting enzyme inhibitors. Am Heart J 131: 153, 1996.
    • (1996) Am Heart J , vol.131 , pp. 153
    • Panina, G.1    Knot, U.N.2    Nunziata, E.3    Cody, R.J.4    Binkley, P.F.5
  • 4
    • 0025153828 scopus 로고
    • Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the studies of left ventricular dysfunction (SOLVD)
    • Francis GS, Benedict C, Johnstone DE, et al. Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the studies of left ventricular dysfunction (SOLVD). Circulation 82: 1724, 1990.
    • (1990) Circulation , vol.82 , pp. 1724
    • Francis, G.S.1    Benedict, C.2    Johnstone, D.E.3
  • 5
    • 0027437764 scopus 로고
    • Comparative neurohormonal responses in patients with preserved and impaired left ventricular ejection fraction: Results of the studies of left ventricular dysfunction (SOLVD) registry. the SOLVD investigators
    • Benedict CR, Weiner DH, Johnstone DE, et al. Comparative neurohormonal responses in patients with preserved and impaired left ventricular ejection fraction: Results of the studies of left ventricular dysfunction (SOLVD) registry. The SOLVD investigators. J Am Coll Cardiol 22: 146A, 1993.
    • (1993) J Am Coll Cardiol , vol.22
    • Benedict, C.R.1    Weiner, D.H.2    Johnstone, D.E.3
  • 7
    • 0031016433 scopus 로고    scopus 로고
    • Increased cardiac adrenergic drive precedes generalized sympathetic activation in human heart failure
    • Rundqvist B, Elam M, Bergmann-Sverrisdottir Y, Eisenhofer G, Friberg P. Increased cardiac adrenergic drive precedes generalized sympathetic activation in human heart failure. Circulation 95: 169, 1997.
    • (1997) Circulation , vol.95 , pp. 169
    • Rundqvist, B.1    Elam, M.2    Bergmann-Sverrisdottir, Y.3    Eisenhofer, G.4    Friberg, P.5
  • 8
    • 0030220104 scopus 로고    scopus 로고
    • Myocardial adrenergic nervous activity is intensified in patients with heart failure without left ventricular volume or pressure overload
    • Imamura Y, Ando H, Ashihara T, Fukuyama T. Myocardial adrenergic nervous activity is intensified in patients with heart failure without left ventricular volume or pressure overload. J Am Coll Cardiol 28: 371, 1996.
    • (1996) J Am Coll Cardiol , vol.28 , pp. 371
    • Imamura, Y.1    Ando, H.2    Ashihara, T.3    Fukuyama, T.4
  • 9
    • 0029845123 scopus 로고    scopus 로고
    • Medical therapy can improve the biological properties of the chronically failing heart: A new era in the treatment of heart failure
    • Eichhorn EJ, Bristow MR. Medical therapy can improve the biological properties of the chronically failing heart: A new era in the treatment of heart failure. Circulation 94: 2285, 1996.
    • (1996) Circulation , vol.94 , pp. 2285
    • Eichhorn, E.J.1    Bristow, M.R.2
  • 10
    • 0026498818 scopus 로고
    • Control of sympathetic nerve activity by vagal mechanoreflexes is blunted in heart failure
    • Dibner-Dunlap ME, Thames MD. Control of sympathetic nerve activity by vagal mechanoreflexes is blunted in heart failure. Circulation 86: 1929, 1992.
    • (1992) Circulation , vol.86 , pp. 1929
    • Dibner-Dunlap, M.E.1    Thames, M.D.2
  • 11
    • 0028012363 scopus 로고
    • Reflex regulation of renal nerve activity in cardiac failure
    • DiBona GF, Sawin LL. Reflex regulation of renal nerve activity in cardiac failure. Am J Physiol 266: R27, 1994.
    • (1994) Am J Physiol , vol.266
    • DiBona, G.F.1    Sawin, L.L.2
  • 12
    • 0027947470 scopus 로고
    • Independent control of skin and muscle sympathetic nerve activity in patients with heart failure
    • Middlekauff HR, Hamilton MA, Steven LW, Mark AL. Independent control of skin and muscle sympathetic nerve activity in patients with heart failure. Circulation 90: 1794, 1994.
    • (1994) Circulation , vol.90 , pp. 1794
    • Middlekauff, H.R.1    Hamilton, M.A.2    Steven, L.W.3    Mark, A.L.4
  • 13
    • 0022492202 scopus 로고
    • Norepinephrine spillover to plasma in patients with congestive heart failure: Evidence of increased overall and cardiorenal sympathetic nerv- Ous activity
    • Hasking GJ, Esler MD, Jennings GL, Burton D, Johns JA, Korner PI. Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nerv- ous activity. Circulation 73: 615, 1986.
    • (1986) Circulation , vol.73 , pp. 615
    • Hasking, G.J.1    Esler, M.D.2    Jennings, G.L.3    Burton, D.4    Johns, J.A.5    Korner, P.I.6
  • 14
    • 0022591615 scopus 로고
    • Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure
    • Leimbach WN, Wallin BG, Victor RG, Aylward PE, Sundlof G, Mark AL. Direct evidence from intraneural recordings for increased central sympathetic outflow in patients with heart failure. Circulation 79: 913, 1986.
    • (1986) Circulation , vol.79 , pp. 913
    • Leimbach, W.N.1    Wallin, B.G.2    Victor, R.G.3    Aylward, P.E.4    Sundlof, G.5    Mark, A.L.6
  • 16
    • 0023266532 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure: Results of the cooperative north Scandinavian enalapril survival study (CONSENSUS)
    • The CONSENSUS Trial Group. Effects of enalapril on mortality in severe congestive heart failure: results of the cooperative north Scandinavian enalapril survival study (CONSENSUS). N Engl J Med 316: 1429, 1987.
    • (1987) N Engl J Med , vol.316 , pp. 1429
  • 17
    • 0025770138 scopus 로고
    • A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure
    • Conn JN, Johnson G, Ziesche S, et al. A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. N Engl J Med 325: 303, 1991.
    • (1991) N Engl J Med , vol.325 , pp. 303
    • Conn, J.N.1    Johnson, G.2    Ziesche, S.3
  • 18
    • 0026547950 scopus 로고
    • Effect of direct vasodilatation with hydralazine versus angiotensin-converting enzyme inhibition with captopril on mortality in advanced heart failure: The Hy-C Trial
    • Fonorow GC, Chelimsky-Fallick C, Stevenson LW, et al. Effect of direct vasodilatation with hydralazine versus angiotensin-converting enzyme inhibition with captopril on mortality in advanced heart failure: the Hy-C Trial. J Am Coll Cardiol 19: 842, 1992.
    • (1992) J Am Coll Cardiol , vol.19 , pp. 842
    • Fonorow, G.C.1    Chelimsky-Fallick, C.2    Stevenson, L.W.3
  • 19
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
    • The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 325: 293, 1991.
    • (1991) N Engl J Med , vol.325 , pp. 293
  • 20
    • 0026785561 scopus 로고
    • Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions
    • The SOLVD Investigators. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. N Engl J Med 327: 685, 1991.
    • (1991) N Engl J Med , vol.327 , pp. 685
  • 21
    • 0026786643 scopus 로고
    • Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: Results of the survival and ventricular enlargement trial (SAVE)
    • for the SAVE Investigators.
    • Pfeffer MA, Braunwald E, Moye LA, et al., for the SAVE Investigators. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the survival and ventricular enlargement trial (SAVE). N Engl J Med 327: 669, 1992.
    • (1992) N Engl J Med , vol.327 , pp. 669
    • Pfeffer, M.A.1    Braunwald, E.2    Moye, L.A.3
  • 22
    • 0028932732 scopus 로고
    • ISIS-4: A randomized factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58050 patients with suspected acute myocardial infarction
    • ISIS-4 Collaborative Group. ISIS-4: A randomized factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58050 patients with suspected acute myocardial infarction. Lancet 345: 669, 1995.
    • (1995) Lancet , vol.345 , pp. 669
  • 23
    • 0028273258 scopus 로고
    • GISSI-3: Effects of lisinopril and transdermal glceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction
    • Gruppo Italiano per lo Studio della Sopravvivenza neil'Infart Miocardico. GISSI-3: Effects of lisinopril and transdermal glceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction. Lancet 343: 1115, 1994.
    • (1994) Lancet , vol.343 , pp. 1115
  • 24
    • 0027423378 scopus 로고
    • Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure
    • The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators. Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. Lancet 342: 821, 1993.
    • (1993) Lancet , vol.342 , pp. 821
  • 25
    • 0028961295 scopus 로고
    • Oral captopril versus placebo among 13634 patients with suspected acute myocardial infarction: Interim report from the Chinese cardiac study (CCS-1)
    • Chinese Cardiac Study Collaborative Study. Oral captopril versus placebo among 13634 patients with suspected acute myocardial infarction: interim report from the Chinese cardiac study (CCS-1). Lancet 345: 686, 1995.
    • (1995) Lancet , vol.345 , pp. 686
  • 26
    • 0028816282 scopus 로고
    • The effect of the angiotensin-converting-enzyme inhibitor zofenopril on the mortality and morbidity after anterior myocardial infarction
    • for the Survival of Myocardial Infarction Long-term Evaluation (SMILE) Study Investigators.
    • Ambrosioni E, Borghi C, Magnani B, for the Survival of Myocardial Infarction Long-term Evaluation (SMILE) Study Investigators. The effect of the angiotensin-converting-enzyme inhibitor zofenopril on the mortality and morbidity after anterior myocardial infarction. N Engl J Med 332: 80, 1995.
    • (1995) N Engl J Med , vol.332 , pp. 80
    • Ambrosioni, E.1    Borghi, C.2    Magnani, B.3
  • 27
    • 0025088737 scopus 로고
    • Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality
    • Swedberg K, Eneroth P, Kjekshus J, Wilhelmsen L. Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. Circulation 82: 1730, 1990.
    • (1990) Circulation , vol.82 , pp. 1730
    • Swedberg, K.1    Eneroth, P.2    Kjekshus, J.3    Wilhelmsen, L.4
  • 28
    • 0015305522 scopus 로고
    • Cardiovascular effects of angiotensin mediated by the central nervous system
    • Ferrario CM, Gildenber PL, McCubbin JW. Cardiovascular effects of angiotensin mediated by the central nervous system. Circ Res 30: 257, 1972.
    • (1972) Circ Res , vol.30 , pp. 257
    • Ferrario, C.M.1    Gildenber, P.L.2    McCubbin, J.W.3
  • 29
    • 11944269310 scopus 로고
    • Centrally infused bradykinin increases baroreceptor reflex sensitivity
    • Gerken VM, Santos RA. Centrally infused bradykinin increases baroreceptor reflex sensitivity. Hypertension 19: II-176, 1992.
    • (1992) Hypertension , vol.19
    • Gerken, V.M.1    Santos, R.A.2
  • 30
    • 0030042369 scopus 로고    scopus 로고
    • Enalaprilat augments arterial and cardiopulmonary baroreflex control of sympathetic nerve activity in patients with heart failure
    • Dibner-Dunlap ME, Smith ML, Kinugawa T, Thames MD. Enalaprilat augments arterial and cardiopulmonary baroreflex control of sympathetic nerve activity in patients with heart failure. J Am Coll Cardiol 27: 358, 1996.
    • (1996) J Am Coll Cardiol , vol.27 , pp. 358
    • Dibner-Dunlap, M.E.1    Smith, M.L.2    Kinugawa, T.3    Thames, M.D.4
  • 31
    • 0030760332 scopus 로고    scopus 로고
    • Effects of chronic ACE inhibition on sympathetic nerve traffic and baroreflex control of circulation in heart failure
    • Grassi G, Cattaneo BM, Seravalle G, et al. Effects of chronic ACE inhibition on sympathetic nerve traffic and baroreflex control of circulation in heart failure. Circulation 96: 1173, 1997.
    • (1997) Circulation , vol.96 , pp. 1173
    • Grassi, G.1    Cattaneo, B.M.2    Seravalle, G.3
  • 32
  • 34
    • 0030902115 scopus 로고    scopus 로고
    • Randomized trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study. ELITE)
    • on behalf of ELITE Study Investigators
    • Pitt B, Segal R, Martinez FA, et al., on behalf of ELITE Study Investigators. Randomized trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study. ELITE). Lancet 349: 747, 1997.
    • (1997) Lancet , vol.349 , pp. 747
    • Pitt, B.1    Segal, R.2    Martinez, F.A.3
  • 35
    • 0016701034 scopus 로고
    • Effect of chronic beta-adrenergic receptor blockade in congestive cardiomyopathy
    • Waagstein F, Hjalmarson A, Varnauskas E, Wallentin I. Effect of chronic beta-adrenergic receptor blockade in congestive cardiomyopathy. Br Heart J 37: 1022, 1975.
    • (1975) Br Heart J , vol.37 , pp. 1022
    • Waagstein, F.1    Hjalmarson, A.2    Varnauskas, E.3    Wallentin, I.4
  • 36
    • 0024430518 scopus 로고
    • Long term beta-blockade in dilated cardiomyopathy: Effects of short and long-term metoprolol treatment followed by withdrawal and readministration of metoprolol
    • Waagstein F, Caidahl K, Wallentin I, Bergh C-H, Hjalmarson A. Long term beta-blockade in dilated cardiomyopathy: effects of short and long-term metoprolol treatment followed by withdrawal and readministration of metoprolol. Circulation 80: 551, 1989.
    • (1989) Circulation , vol.80 , pp. 551
    • Waagstein, F.1    Caidahl, K.2    Wallentin, I.3    Bergh, C.-H.4    Hjalmarson, A.5
  • 37
    • 0018759507 scopus 로고
    • Prolongation of survival in congestive cardiomyopathy by beta-receptor blockade
    • Swedberg K, Waagstein F, Hjalmarson A, Wallentin I. Prolongation of survival in congestive cardiomyopathy by beta-receptor blockade. Lancet 1: 1374, 1979.
    • (1979) Lancet , vol.1 , pp. 1374
    • Swedberg, K.1    Waagstein, F.2    Hjalmarson, A.3    Wallentin, I.4
  • 38
    • 0027135308 scopus 로고
    • Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy
    • for the Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group
    • Waagstein F, Bristow MR, Swedberg K, et al., for the Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group. Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Lancet 342: 1441, 1993.
    • (1993) Lancet , vol.342 , pp. 1441
    • Waagstein, F.1    Bristow, M.R.2    Swedberg, K.3
  • 39
    • 0028092116 scopus 로고
    • A randomized trial of beta-block ade in heart failure: The cardiac insufficiency bisoprolol study (CIBIS)
    • CIBIS Investigators and Committees. A randomized trial of beta-block ade in heart failure: The cardiac insufficiency bisoprolol study (CIBIS). Circulation 90: 1765, 1994.
    • (1994) Circulation , vol.90 , pp. 1765
  • 40
    • 10544251442 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure: The PRECISE trial
    • for the PRECISE Study Group.
    • Packer M, Colucci WS, Sackner-Berstein JD, et al., for the PRECISE Study Group. Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure: the PRECISE trial. Circulation 94: 2793, 1996.
    • (1996) Circulation , vol.94 , pp. 2793
    • Packer, M.1    Colucci, W.S.2    Sackner-Berstein, J.D.3
  • 41
    • 0029845423 scopus 로고    scopus 로고
    • Comparative hemodynamic, left ventricular function, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing heart
    • Gilbert EM, Abraham WT, Olsen S, et al. Comparative hemodynamic, left ventricular function, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in the failing heart. Circulation 94: 2817, 1996.
    • (1996) Circulation , vol.94 , pp. 2817
    • Gilbert, E.M.1    Abraham, W.T.2    Olsen, S.3
  • 42
    • 0029937949 scopus 로고    scopus 로고
    • The effect of carvedilol on morbidity and mortality inpatients with chronic heart failure
    • for the US Carvedilil Heart Failure Study Group
    • Packer M, Bristow MR, Cohn JN, Colucci WS, Fowler MB, Gilbert EM, Shusterman NH, for the US Carvedilil Heart Failure Study Group. The effect of carvedilol on morbidity and mortality inpatients with chronic heart failure. N Engl J Med 334: 1349, 1996.
    • (1996) N Engl J Med , vol.334 , pp. 1349
    • Packer, M.1    Bristow, M.R.2    Cohn, J.N.3    Colucci, W.S.4    Fowler, M.B.5    Gilbert, E.M.6    Shusterman, N.H.7
  • 43
    • 10544223267 scopus 로고    scopus 로고
    • Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure
    • Bristow MR, Gilbert EM, Abraham WT, et al. Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure. Circulation 94: 2807, 1996.
    • (1996) Circulation , vol.94 , pp. 2807
    • Bristow, M.R.1    Gilbert, E.M.2    Abraham, W.T.3
  • 44
    • 0029988170 scopus 로고    scopus 로고
    • β-adrenergic blockers and survival in heart failure
    • Pfeffer MA, Stevenson LW. β-adrenergic blockers and survival in heart failure. K Engl J Med 334: 1396, 1996.
    • (1996) K Engl J Med , vol.334 , pp. 1396
    • Pfeffer, M.A.1    Stevenson, L.W.2
  • 45
    • 0029919877 scopus 로고    scopus 로고
    • Cardiac adrenergic receptor effects of carvedilol
    • Yoshikawa T, Port JD, Asano K, et al. Cardiac adrenergic receptor effects of carvedilol. Eur Heart J 17 (suppl B): 8, 1996.
    • (1996) Eur Heart J , vol.17 , Issue.SUPPL. B , pp. 8
    • Yoshikawa, T.1    Port, J.D.2    Asano, K.3
  • 46
    • 0023130760 scopus 로고
    • Pharmacological profile of carvedilol as a beta-blocking agent with vasodilating and hypolensive properties
    • Sponer G, Bartsch W, Strein K, Muller-Beckman B, Boehm E. Pharmacological profile of carvedilol as a beta-blocking agent with vasodilating and hypolensive properties. J Cardiovasc Pharmacol 9: 317, 1987.
    • (1987) J Cardiovasc Pharmacol , vol.9 , pp. 317
    • Sponer, G.1    Bartsch, W.2    Strein, K.3    Muller-Beckman, B.4    Boehm, E.5
  • 47
    • 0021150852 scopus 로고
    • Sympathetic outflow to muscles during treatment of hypertension with metoprolol
    • Wallin BG, Sundolf G, Stromgren E, Aberg H. Sympathetic outflow to muscles during treatment of hypertension with metoprolol. Hypertension 6: 557, 1984.
    • (1984) Hypertension , vol.6 , pp. 557
    • Wallin, B.G.1    Sundolf, G.2    Stromgren, E.3    Aberg, H.4
  • 48
    • 0029150426 scopus 로고
    • Reduction in muscle sympathetic nerve activity after long term metoprolol for dilated cardiomyopathy: Preliminary observations
    • Rahman MA, Hara K, Daly PA, Wigle ED, Floras JS. Reduction in muscle sympathetic nerve activity after long term metoprolol for dilated cardiomyopathy: preliminary observations. Br Heart J 74: 431, 1995.
    • (1995) Br Heart J , vol.74 , pp. 431
    • Rahman, M.A.1    Hara, K.2    Daly, P.A.3    Wigle, E.D.4    Floras, J.S.5
  • 49
    • 0027216221 scopus 로고
    • Withdrawal of digoxin from patients with chronic heart failure treated with angiotensin-converting-enzyme inhibitors
    • Packer M, Gheorghiade M, Young JB, et al. Withdrawal of digoxin from patients with chronic heart failure treated with angiotensin-converting-enzyme inhibitors. N Engl J Med 329: 1, 1993.
    • (1993) N Engl J Med , vol.329 , pp. 1
    • Packer, M.1    Gheorghiade, M.2    Young, J.B.3
  • 50
    • 0027436528 scopus 로고
    • Randomized study assessing the effect of digoxin withdrawal in patients with mild to moderate chronic congestive heart failure: Results of the PROVED trial
    • Uretsky BF, Young JB, Shahidi FE, Yellen LG, Harrison MC, Jolly MK. Randomized study assessing the effect of digoxin withdrawal in patients with mild to moderate chronic congestive heart failure: Results of the PROVED trial. J Am Coll Cardiol 22: 955, 1993.
    • (1993) J Am Coll Cardiol , vol.22 , pp. 955
    • Uretsky, B.F.1    Young, J.B.2    Shahidi, F.E.3    Yellen, L.G.4    Harrison, M.C.5    Jolly, M.K.6
  • 51
    • 0031051347 scopus 로고    scopus 로고
    • The effect of digoxin on mortality and morbidity in patients with heart failure
    • The Digitalis Investigation Group. The effect of digoxin on mortality and morbidity in patients with heart failure. New Engl J Med 336: 525, 1997.
    • (1997) New Engl J Med , vol.336 , pp. 525
  • 52
    • 0019082477 scopus 로고
    • Sensitization of cardiac receptors (vagal afferents) by intracoronary acetylstrophanthidin
    • Thames MD, Waickman LA, Abboud FM. Sensitization of cardiac receptors (vagal afferents) by intracoronary acetylstrophanthidin. Am J Physiol 239: H628, 1980.
    • (1980) Am J Physiol , vol.239
    • Thames, M.D.1    Waickman, L.A.2    Abboud, F.M.3
  • 53
    • 0024402581 scopus 로고
    • Sympathoinhibitory responses to digitalis glycosides in heart failure patients: Direct evidence from sympathetic neural recordings
    • Ferguson DW, Berg WJ, Sanders JS, Roach PJ, Kempf JS, Kienzle MG. Sympathoinhibitory responses to digitalis glycosides in heart failure patients: direct evidence from sympathetic neural recordings. Circulation 80: 65, 1989.
    • (1989) Circulation , vol.80 , pp. 65
    • Ferguson, D.W.1    Berg, W.J.2    Sanders, J.S.3    Roach, P.J.4    Kempf, J.S.5    Kienzle, M.G.6
  • 55
    • 4243452177 scopus 로고
    • Sensitization of vagal cardiopulmonary baroreflex by chronic digoxin
    • Thames MD, Miller BD, Abboud FM. Sensitization of vagal cardiopulmonary baroreflex by chronic digoxin. Am J Physiol 243: H815, 1982.
    • (1982) Am J Physiol , vol.243
    • Thames, M.D.1    Miller, B.D.2    Abboud, F.M.3
  • 59
    • 0016155835 scopus 로고
    • A Comparison of regional blood flow and oxygen utilization during dynamic forearm exercise in normal subjects and patients with congestive heart failure
    • Zelis R, Longhurst J, Capone RJ, Mason DT. A Comparison of regional blood flow and oxygen utilization during dynamic forearm exercise in normal subjects and patients with congestive heart failure. Circulation 50: 137, 1974.
    • (1974) Circulation , vol.50 , pp. 137
    • Zelis, R.1    Longhurst, J.2    Capone, R.J.3    Mason, D.T.4
  • 61
    • 0026734679 scopus 로고
    • Controlled trial of physical training in chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function
    • Coats AJS, Adamopoulos S, Radaelli A, et al. Controlled trial of physical training in chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function. Circulation 85: 2119, 1992.
    • (1992) Circulation , vol.85 , pp. 2119
    • Coats, A.J.S.1    Adamopoulos, S.2    Radaelli, A.3
  • 62
    • 0030317617 scopus 로고    scopus 로고
    • Exercise training in patients with heart failure. A randomized, rontrolled trial
    • Keteyian SJ, Levine AB, Brawner CA, et al. Exercise training in patients with heart failure. A randomized, rontrolled trial. Ann Intern Med 124: 1051, 1996.
    • (1996) Ann Intern Med , vol.124 , pp. 1051
    • Keteyian, S.J.1    Levine, A.B.2    Brawner, C.A.3
  • 63
    • 0031195043 scopus 로고    scopus 로고
    • Predictors of response to exercise training in severe chronic congestive heart failure
    • Meyer K, Görnandt L, Schwaibold, et al. Predictors of response to exercise training in severe chronic congestive heart failure. Am J Cardiol 80: 56, 1997.
    • (1997) Am J Cardiol , vol.80 , pp. 56
    • Meyer, K.1    Görnandt, L.2    Schwaibold3
  • 64
    • 0018709748 scopus 로고
    • Long-term effects of physical training on coronary patients with impaired ventricular function
    • Lee AP, Ice R, Blessy R, Sanmarco ME. Long-term effects of physical training on coronary patients with impaired ventricular function. Circulation 60: 1519, 1979.
    • (1979) Circulation , vol.60 , pp. 1519
    • Lee, A.P.1    Ice, R.2    Blessy, R.3    Sanmarco, M.E.4
  • 65
    • 0029007903 scopus 로고
    • Reversal of autonomic derangements by physical training in chronic heart failure assessed by heart rate variability
    • Kiilavuori K, Toivonen L, Näveri H, Leinon H. Reversal of autonomic derangements by physical training in chronic heart failure assessed by heart rate variability. Eur Heart J 16: 490, 1995.
    • (1995) Eur Heart J , vol.16 , pp. 490
    • Kiilavuori, K.1    Toivonen, L.2    Näveri, H.3    Leinon, H.4
  • 67
    • 0029882388 scopus 로고    scopus 로고
    • Influence of exercise training and restriction of activity on autonomie balance in patients with severe congestive heart failure
    • Toepfer M, Meyer K, Maier P, Dambacher M, Theisen K, Roskamm H, Frey AW. Influence of exercise training and restriction of activity on autonomie balance in patients with severe congestive heart failure. Clin Sci 91 (Suppl): 116, 1996.
    • (1996) Clin Sci , vol.91 , Issue.SUPPL. , pp. 116
    • Toepfer, M.1    Meyer, K.2    Maier, P.3    Dambacher, M.4    Theisen, K.5    Roskamm, H.6    Frey, A.W.7
  • 68
    • 0029984813 scopus 로고    scopus 로고
    • After-effects of exercise on haemodynamics and muscle sympathetic nerve activity in young patients with dilated cardiomyopathy
    • Hara K, Floras JS. After-effects of exercise on haemodynamics and muscle sympathetic nerve activity in young patients with dilated cardiomyopathy. Heart 75: 602, 1996.
    • (1996) Heart , vol.75 , pp. 602
    • Hara, K.1    Floras, J.S.2


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