메뉴 건너뛰기




Volumn 77, Issue 1, 1998, Pages 31-39

Protective effects of ranolazine, a novel anti-ischemic drug, on the hydrogen peroxide-induced derangements in isolated, perfused rat heart: Comparison with dichloroacetate

Author keywords

Dichloroacetate; Hydrogen peroxide; Lipid peroxidation; Ranolazine; Rat heart

Indexed keywords

ADENOSINE TRIPHOSPHATE; DICHLOROACETIC ACID; HYDROGEN PEROXIDE; PYRUVATE DEHYDROGENASE; RANOLAZINE;

EID: 0031746154     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.77.31     Document Type: Article
Times cited : (38)

References (30)
  • 1
    • 0025134189 scopus 로고
    • Prevention of myocardial enzyme release by ranolazine in a primate model of ischaemia with reperfusion
    • Allely MC and Alps BJ: Prevention of myocardial enzyme release by ranolazine in a primate model of ischaemia with reperfusion. Br J Pharmacol 99, 5-6 (1990)
    • (1990) Br J Pharmacol , vol.99 , pp. 5-6
    • Allely, M.C.1    Alps, B.J.2
  • 3
    • 0027241659 scopus 로고
    • Protective effects of ranolazine in guinea pig hearts during low-flow ischaemia and their association with increases in active pyruvate dehydrogenase
    • Clarke B, Spedding M, Patmore L and McCormack JC: Protective effects of ranolazine in guinea pig hearts during low-flow ischaemia and their association with increases in active pyruvate dehydrogenase. Br J Pharmacol 109, 748-750 (1993)
    • (1993) Br J Pharmacol , vol.109 , pp. 748-750
    • Clarke, B.1    Spedding, M.2    Patmore, L.3    McCormack, J.C.4
  • 5
    • 0030032681 scopus 로고    scopus 로고
    • Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts
    • McCormack JG, Barr RL, Wolff AA and Lopaschuk GD: Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts. Circulation 93, 135-142 (1996)
    • (1996) Circulation , vol.93 , pp. 135-142
    • McCormack, J.G.1    Barr, R.L.2    Wolff, A.A.3    Lopaschuk, G.D.4
  • 6
    • 0026680239 scopus 로고
    • Effects of a new metabolic modulator, ranolazine, on exercise tolerance in angina pectoris patients treated with beta-blocker or diltiazem
    • Cocco G, Rousseau MF, Bouvy T, Cheron P, Williams G, Detry JM and Pouleur H: Effects of a new metabolic modulator, ranolazine, on exercise tolerance in angina pectoris patients treated with beta-blocker or diltiazem. J Cardiovasc Pharmacol 20, 131-138 (1992)
    • (1992) J Cardiovasc Pharmacol , vol.20 , pp. 131-138
    • Cocco, G.1    Rousseau, M.F.2    Bouvy, T.3    Cheron, P.4    Williams, G.5    Detry, J.M.6    Pouleur, H.7
  • 7
    • 0342858278 scopus 로고
    • Improvement in exercise tolerance and left ventricular filling dynamics in patients with angina pectoris with the novel metabolic modulator, ranolazine
    • Bouvy T, Rousseau MF, Cocco G, Cheron P, William GJ and Detry JMR: Improvement in exercise tolerance and left ventricular filling dynamics in patients with angina pectoris with the novel metabolic modulator, ranolazine. Acta Cardiol 48, 98-99 (1993)
    • (1993) Acta Cardiol , vol.48 , pp. 98-99
    • Bouvy, T.1    Rousseau, M.F.2    Cocco, G.3    Cheron, P.4    William, G.J.5    Detry, J.M.R.6
  • 8
    • 0021591159 scopus 로고
    • Molecular oxygen: Friend and foe: the role of the oxygen free radical system in the calcium paradox, the oxygen paradox and ischemia/reperfusion injury
    • Hess ML and Manson NH: Molecular oxygen: friend and foe: the role of the oxygen free radical system in the calcium paradox, the oxygen paradox and ischemia/reperfusion injury. J Mol Cell Cardiol 16, 969-985 (1984)
    • (1984) J Mol Cell Cardiol , vol.16 , pp. 969-985
    • Hess, M.L.1    Manson, N.H.2
  • 9
    • 0025369854 scopus 로고
    • Myocardial ischemia, reperfusion and free radical injury
    • Lucchesi BR: Myocardial ischemia, reperfusion and free radical injury. Am J Cardiol 65, 141-231 (1990)
    • (1990) Am J Cardiol , vol.65 , pp. 141-231
    • Lucchesi, B.R.1
  • 10
    • 0026337506 scopus 로고
    • Oxidative damage to the myocardium: A fundamental mechanism of myocardial injury
    • Loesser KE, Kukreja RC, Kazziha SY, Jesse RL and Hess ML: Oxidative damage to the myocardium: a fundamental mechanism of myocardial injury. Cardioscience 2, 199-216 (1991)
    • (1991) Cardioscience , vol.2 , pp. 199-216
    • Loesser, K.E.1    Kukreja, R.C.2    Kazziha, S.Y.3    Jesse, R.L.4    Hess, M.L.5
  • 11
    • 0023485745 scopus 로고
    • Electrophysiological derangements induced by lipid peroxidation in cardiac tissue
    • Nakaya H, Tohse N and Kanno M: Electrophysiological derangements induced by lipid peroxidation in cardiac tissue. Am J Physiol 253, H1089-H1097 (1987)
    • (1987) Am J Physiol , vol.253
    • Nakaya, H.1    Tohse, N.2    Kanno, M.3
  • 12
    • 0024457262 scopus 로고
    • Reduction of lipid peroxidation in reperfused isolated rabbit hearts by diltiazem
    • Koller PT and Bergmann SR: Reduction of lipid peroxidation in reperfused isolated rabbit hearts by diltiazem. Circ Res 65, 838-846 (1989)
    • (1989) Circ Res , vol.65 , pp. 838-846
    • Koller, P.T.1    Bergmann, S.R.2
  • 13
    • 0030051019 scopus 로고    scopus 로고
    • Propofol attenuates hydrogen peroxide-induced mechanical and metabolic derangements in the isolated rat heart
    • Kokita N and Hara A: Propofol attenuates hydrogen peroxide-induced mechanical and metabolic derangements in the isolated rat heart. Anesthesiology 84, 117-127 (1996)
    • (1996) Anesthesiology , vol.84 , pp. 117-127
    • Kokita, N.1    Hara, A.2
  • 14
    • 0027142787 scopus 로고
    • Lidocaine attenuates both mechanical and metabolic changes induced by hydrogen peroxide in the rat heart
    • Hara A, Matsumura H and Abiko Y: Lidocaine attenuates both mechanical and metabolic changes induced by hydrogen peroxide in the rat heart. Am J Physiol 265, H1478-H1485 (1993)
    • (1993) Am J Physiol , vol.265
    • Hara, A.1    Matsumura, H.2    Abiko, Y.3
  • 15
    • 0030437245 scopus 로고    scopus 로고
    • Protective effects of dilazep and its novel derivative, K-7259, on mechanical and metabolic derangements induced by hydrogen peroxide in the isolated perfused rat heart
    • Hara A and Abiko Y: Protective effects of dilazep and its novel derivative, K-7259, on mechanical and metabolic derangements induced by hydrogen peroxide in the isolated perfused rat heart. J Pharmacol Exp Ther 277, 565-571 (1996)
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 565-571
    • Hara, A.1    Abiko, Y.2
  • 16
    • 26844563385 scopus 로고    scopus 로고
    • Effects of prazosin on myocardial derangements induced by hydrogen peroxide in the isolated rat heart
    • Akahira M, Hara A, Hashizume H and Abiko Y: Effects of prazosin on myocardial derangements induced by hydrogen peroxide in the isolated rat heart. J Mol Cell Cardiol 29, A285 (1997)
    • (1997) J Mol Cell Cardiol , vol.29
    • Akahira, M.1    Hara, A.2    Hashizume, H.3    Abiko, Y.4
  • 17
    • 0024452528 scopus 로고
    • The pharmacology of dichloroacetate
    • Stacpoole PW: The pharmacology of dichloroacetate. Metabolism 38, 1124-1144 (1989)
    • (1989) Metabolism , vol.38 , pp. 1124-1144
    • Stacpoole, P.W.1
  • 18
    • 0025169628 scopus 로고
    • Dichloroacetate stimulation of glucose oxidation improves recovery of ischemic rat hearts
    • Mcveigh JJ and Lopaschuk GD: Dichloroacetate stimulation of glucose oxidation improves recovery of ischemic rat hearts. Am J Physiol 259, H1079-H1085 (1990)
    • (1990) Am J Physiol , vol.259
    • Mcveigh, J.J.1    Lopaschuk, G.D.2
  • 19
    • 0029996458 scopus 로고    scopus 로고
    • Ranolazine increases active pyruvate dehydrogenase in perfused normoxic rat hearts: Evidence for an indirect mechanism
    • Clarke B, Wyatt KM and McCormack JG: Ranolazine increases active pyruvate dehydrogenase in perfused normoxic rat hearts: evidence for an indirect mechanism. J Mol Cell Cardiol 28, 341-350 (1996)
    • (1996) J Mol Cell Cardiol , vol.28 , pp. 341-350
    • Clarke, B.1    Wyatt, K.M.2    McCormack, J.G.3
  • 21
    • 0021811414 scopus 로고
    • Studies on cumen hydroperoxide-induced lipid peroxidation in the isolated perfused rat heart
    • Koster JF, Slee RG, Essed CE and Stam H: Studies on cumen hydroperoxide-induced lipid peroxidation in the isolated perfused rat heart. J Mol Cell Cardiol 17, 701-708 (1985)
    • (1985) J Mol Cell Cardiol , vol.17 , pp. 701-708
    • Koster, J.F.1    Slee, R.G.2    Essed, C.E.3    Stam, H.4
  • 22
    • 0023922349 scopus 로고
    • Xanthine oxidase produces hydrogen peroxide which contributes to reperfusion injury of ischemic, isolated, perfused rat hearts
    • Brown JM, Terada LS , Grosso MA, Whitmann GJ, Velasco SE, Patt A, Harken AH and Repine JE: Xanthine oxidase produces hydrogen peroxide which contributes to reperfusion injury of ischemic, isolated, perfused rat hearts. J Clin Invest 81, 1297-1301 (1988)
    • (1988) J Clin Invest , vol.81 , pp. 1297-1301
    • Brown, J.M.1    Terada, L.S.2    Grosso, M.A.3    Whitmann, G.J.4    Velasco, S.E.5    Patt, A.6    Harken, A.H.7    Repine, J.E.8
  • 23
    • 0002653533 scopus 로고
    • Intracellular production of oxygen-derived free radicals
    • Edited by Halliwell B, The Upjohn Company, Bethesda
    • Fisher AB: Intracellular production of oxygen-derived free radicals. In Oxygen Radicals and Tissue Injury, Edited by Halliwell B, pp 34-39, The Upjohn Company, Bethesda (1988)
    • (1988) Oxygen Radicals and Tissue Injury , pp. 34-39
    • Fisher, A.B.1
  • 24
    • 0025897538 scopus 로고
    • Evaluation of phospholipid peroxidation as malondialdehyde during myocardial ischemia and reperfusion injury
    • Ceconi C, Cargnoni A, Pasini E, Condorelli E, Curello S and Ferrari R: Evaluation of phospholipid peroxidation as malondialdehyde during myocardial ischemia and reperfusion injury. Am J Physiol 260, H1057-H1061 (1991)
    • (1991) Am J Physiol , vol.260
    • Ceconi, C.1    Cargnoni, A.2    Pasini, E.3    Condorelli, E.4    Curello, S.5    Ferrari, R.6
  • 25
    • 0026355879 scopus 로고
    • Myocardial protection by R56865: A new principle based on prevention of ion channel pathology
    • Ver Donck L and Borgers M: Myocardial protection by R56865: a new principle based on prevention of ion channel pathology. Am J Physiol 261, H1828-H1835 (1991)
    • (1991) Am J Physiol , vol.261
    • Ver Donck, L.1    Borgers, M.2
  • 26
    • 0030957101 scopus 로고    scopus 로고
    • Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes
    • Lond
    • Ward CA and Giles WR: Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes. J Physiol (Lond) 500, 631-642 (1997)
    • (1997) J Physiol , vol.500 , pp. 631-642
    • Ward, C.A.1    Giles, W.R.2
  • 27
    • 33750740174 scopus 로고    scopus 로고
    • 2+ exchange in ventricular myocytes
    • 2+ exchange in ventricular myocytes. Am J Physiol 271, H823-H833 (1996)
    • (1996) Am J Physiol , vol.271
    • Goldhaber, J.I.1
  • 28
  • 29
    • 0026513613 scopus 로고
    • Oxygen free radical-mediated selective endothelial dysfunction in isolated coronary artery
    • Todoki K, Okabe E, Kiyose T, Sekishita T and Ito H: Oxygen free radical-mediated selective endothelial dysfunction in isolated coronary artery. Am J Physiol 262, H806-H812 (1992)
    • (1992) Am J Physiol , vol.262
    • Todoki, K.1    Okabe, E.2    Kiyose, T.3    Sekishita, T.4    Ito, H.5
  • 30
    • 85047679946 scopus 로고
    • Effects of nisoldipine upon endothelial dysfunction following ischaemic and peroxidative injury in the perfused rat heart
    • Yaghi MM and Watts JA: Effects of nisoldipine upon endothelial dysfunction following ischaemic and peroxidative injury in the perfused rat heart. Cardiovasc Res 27, 990-996 (1993)
    • (1993) Cardiovasc Res , vol.27 , pp. 990-996
    • Yaghi, M.M.1    Watts, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.