A simple and efficient synthesis of 1,6-disubstituted 1,4,5,6- tetrahydropyridazines by ring enlargement of 2,5-dibenzotriazolyl-N- aminopyrrolidines

Synthesis

Volumn , Issue 11, 1998, Pages 1627-1630

  Katritzky, Alan R ^a   Pleynet, David P M ^a   Yang, Baozhen ^a   Yao, Jiangchao ^a  

^a University of Florida ^*  (United States)

Author keywords

1,6 disubstituted 1,4,5,6 tetrahydropyridazines; Grignard reagents; Hydrazines; Ring enlargement; Succinic dialdehyde

Indexed keywords

2,5 BISBENZOTRIAZOLYL N PHENYLAMINOPYRROLIDINE; 6 METHYL 1 PHENYL 1,4,5.6 TETRAHYDROPYRIDAZINE; ANTIDEPRESSANT AGENT; ANTIINFLAMMATORY AGENT; CARDIOVASCULAR AGENT; FUNGICIDE; HERBICIDE; PYRIDAZINE DERIVATIVE; UNCLASSIFIED DRUG;

AGRICULTURE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARDIOVASCULAR DISEASE; DEPRESSION; DRUG CONFORMATION; DRUG EFFECT; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

EID: 0031743274     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-2200     Document Type: Article

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