-
1
-
-
0005267724
-
Evaluating the role of polymorphic drug-metabolising enzymes in the pharmaceutical industry - Impact on drug candidate selection and advancement
-
Ball S 1997 Evaluating the role of polymorphic drug-metabolising enzymes in the pharmaceutical industry - impact on drug candidate selection and advancement. IBC's Third Annual Conference on Pharmacogenetics
-
(1997)
IBC's Third Annual Conference on Pharmacogenetics
-
-
Ball, S.1
-
3
-
-
0029979414
-
Polymorphic drug oxidation - Relevance to the treatment of psychiatric disorders
-
Bertilsson L, Dahl ML 1996 Polymorphic drug oxidation - relevance to the treatment of psychiatric disorders. CNS Drugs 5: 200-223
-
(1996)
CNS Drugs
, vol.5
, pp. 200-223
-
-
Bertilsson, L.1
Dahl, M.L.2
-
4
-
-
0025950370
-
Debrisoquine/sparteine hydroxylation genotype and phenotype: Analysis of common mutations and alleles of CYP2D6 in a European population
-
Broly F, Gaedigk A, Heim M, Eichelbaum M, Morike K, Meyer UA 1991 Debrisoquine/sparteine hydroxylation genotype and phenotype: Analysis of common mutations and alleles of CYP2D6 in a European population. DNA Cell Biol 10: 545-558
-
(1991)
DNA Cell Biol
, vol.10
, pp. 545-558
-
-
Broly, F.1
Gaedigk, A.2
Heim, M.3
Eichelbaum, M.4
Morike, K.5
Meyer, U.A.6
-
5
-
-
10544248170
-
The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: Screening costs and influence on clinical outcomes in psychiatry
-
Chen SQ, Chou WH, Blouin RA, Mao ZP, Humphries LL, Meek C, Neill JR, Martin WL, Hays LR, Wedlund PJ 1996 The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: Screening costs and influence on clinical outcomes in psychiatry. Clin Pharm Ther 60: 522-534
-
(1996)
Clin Pharm Ther
, vol.60
, pp. 522-534
-
-
Chen, S.Q.1
Chou, W.H.2
Blouin, R.A.3
Mao, Z.P.4
Humphries, L.L.5
Meek, C.6
Neill, J.R.7
Martin, W.L.8
Hays, L.R.9
Wedlund, P.J.10
-
6
-
-
0026496950
-
The role of individual cytochromes P450 in drug metabolism and clinical response
-
Cholerton S, Daly AK Idle JR 1992 The role of individual cytochromes P450 in drug metabolism and clinical response. TIPS 13: 434-439
-
(1992)
TIPS
, vol.13
, pp. 434-439
-
-
Cholerton, S.1
Daly, A.K.2
Idle, J.R.3
-
7
-
-
0028856846
-
Molecular basis of polymorphic drug metabolism
-
Daly AK 1995 Molecular basis of polymorphic drug metabolism. J Mol Med 73: 539-553
-
(1995)
J Mol Med
, vol.73
, pp. 539-553
-
-
Daly, A.K.1
-
8
-
-
0028568658
-
Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility
-
Daly AK, Cholerton S, Armstrong M, Idle JR 1994 Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility. Environ Health Perspect 102: 55-61
-
(1994)
Environ Health Perspect
, vol.102
, pp. 55-61
-
-
Daly, A.K.1
Cholerton, S.2
Armstrong, M.3
Idle, J.R.4
-
9
-
-
0029683112
-
Antipyrine as a probe for human oxidative drug metabolism - Identification of the cytochrome P450 enzymes catalysing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation
-
Engel G, Hofmann U, Heidemann H, Cosme J, Eichelbaum M 1996 Antipyrine as a probe for human oxidative drug metabolism - identification of the cytochrome P450 enzymes catalysing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation. Clin Pharmacol Ther 59: 613-623
-
(1996)
Clin Pharmacol Ther
, vol.59
, pp. 613-623
-
-
Engel, G.1
Hofmann, U.2
Heidemann, H.3
Cosme, J.4
Eichelbaum, M.5
-
10
-
-
0030712276
-
Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolising enzymes
-
Frye RF, Matzke GR, Adedoyin A, Porter JA, Branch RA 1997 Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolising enzymes. Clin Pharmacol Ther 62: 365-376
-
(1997)
Clin Pharmacol Ther
, vol.62
, pp. 365-376
-
-
Frye, R.F.1
Matzke, G.R.2
Adedoyin, A.3
Porter, J.A.4
Branch, R.A.5
-
11
-
-
0027983085
-
Pharmacogenetic phenotyping and genotyping - Present status and future potential
-
Gonzalez FJ, Idle JR 1994 Pharmacogenetic phenotyping and genotyping - Present status and future potential. Clin Pharmacokinet 26, 59-70
-
(1994)
Clin Pharmacokinet
, vol.26
, pp. 59-70
-
-
Gonzalez, F.J.1
Idle, J.R.2
-
12
-
-
0029076365
-
Pharmacogenetics in clinical pharmacology and toxicology
-
Inaba T, Nebert DW, Burchell B, Watkins PB, Goldstein JA, Bertilsson L, Tucker GT 1995. Pharmacogenetics in clinical pharmacology and toxicology. Can J Physiol Pharmacol 73: 331-338
-
(1995)
Can J Physiol Pharmacol
, vol.73
, pp. 331-338
-
-
Inaba, T.1
Nebert, D.W.2
Burchell, B.3
Watkins, P.B.4
Goldstein, J.A.5
Bertilsson, L.6
Tucker, G.T.7
-
13
-
-
0030897275
-
Use of probe drugs as predictors of drug metabolism in humans
-
Kivistö KT, Kroemer HK 1997 Use of probe drugs as predictors of drug metabolism in humans. J Clin Pharmacol 37:40S-48S
-
(1997)
J Clin Pharmacol
, vol.37
-
-
Kivistö, K.T.1
Kroemer, H.K.2
-
14
-
-
0242477470
-
Relevance and means of assessing induction and inhibition of drug metabolism in man
-
Park BK, Kitteringham NR 1988 Relevance and means of assessing induction and inhibition of drug metabolism in man. Prog Drug Metab 11: 1-60
-
(1988)
Prog Drug Metab
, vol.11
, pp. 1-60
-
-
Park, B.K.1
Kitteringham, N.R.2
|