Distinct roles for B7 costimulation in contact hypersensitivity and humoral immune responses to epicutaneous antigen

European Journal of Immunology

Volumn 28, Issue 12, 1998, Pages 4221-4227

  Rauschmayr Kopp, Tamara ^a,d   Williams, Ifor R ^a,e   Borriello, Frank ^b   Sharpe, Arlene H ^b   Kupper, Thomas S ^a,c  

^a Harvard Skin Disease Research Center   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD INSTITUTES OF MEDICINE   (United States)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

B7 1; B7 2; CD28; Contact hypersensitivity; Costimulation

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; HAPTEN; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; OXAZOLONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTACT ALLERGY; CONTROLLED STUDY; HUMORAL IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION; T LYMPHOCYTE ACTIVATION;

EID: 0031739036     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199812)28:12<4221::AID-IMMU4221>3.0.CO;2-M     Document Type: Article

References (32)

1. Mueller, D. L., Jenkins, M. K. and Schwartz, R. H., Clonal expansion versus functional clonal inactivation: a costimulatory signaling pathway determines the outcome of T cell antigen receptor occupancy. Annu. Rev. Immunol. 1989. 7: 445-480.
2. Schwartz, R., A cell culture model for T lymphocyte clonal anergy. Science 1990. 248: 1349-1356.
3. Hathcock, K. S., Laszlo, G., Dickler, H., Bradshaw, J., Linsley, P. and Modes, R. J., Identification of a novel CTLA-4 ligand that is costimulatory for T cell activation. Science 1993. 262: 905-907.
4. Freeman, G. J., Borriello, F., Hodes, R. J., Reiser, H., Gribben, J. G., Ng, J. W., Kim, J., Goldberg, J. M., Hathcock, K., Laszlo, G., Lombard, L. A., Wang, S., Gray, G. S., Nadler, L. M. and Sharpe, A. H., Murine B7-2, an alternative CTLA-4 counter-receptor that costimulates T cell proliferation and interleukin 2 production. J. Exp. Med. 1993. 178: 2185-2192.
5. Freeman, G. J., Gribben, J. G., Boussiotis, V. A., Ng, J. W., Restivo, V. A., Jr., Lombard, L. A., Gray, G. S. and Nadler, L. M., Cloning of B7-2: a CTLA-4 counterreceptor that costimulates human T cell proliferation. Science 1993. 262: 909-911.
6. Gimmi, C. D., Freeman, G. J., Gribben, J. G., Sugita, K., Freedman, A. S., Morimoto, C. and Nadler, L. M., B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2. Proc. Natl. Acad. Sci. USA 1991. 88: 6575-6579.
7. Tivol, E. A., Borriello, F., Schweitzer, A. N., Lynch, W. P., Bluestone, J. A. and Sharpe, A. H., Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995. 3: 541-547.
8. Cross, A. H., Girard, T. J., Giacoletto, K. S., Evans, R. J., Keeling, R. M., Lin, R. F., Trotter, J. L. and Karr, R. W., Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation. J. Clin. Invest. 1995. 95: 2783-2789.
9. Finck, B. K., Linsley, P. S. and Wofsy, D., Treatment of murine lupus with CTLA-4 Ig. Science 1994. 265: 1225-1227.
10. Turka, L. A., Linsley, P. S., Lin, H., Brady, W., Leiden, J. M., Wei, R. Q., Gibson, M. L., Zheng, X. G., Myrdal, S., Gordon, D., Bailey, T., Boiling, S. and Thompson, C. B., T cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo. Proc. Natl. Acad. Sci. USA 1992. 89: 11102-11105.
11. Xu, H., Dilulio, N. A. and Fairchild, R. L., T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: Interferon γ-producing (Tc1) effector CD8+ T cells and interleukin (II) 4/II-10-producing (Th2) negative regulatory CD4+ T cells. J. Exp. Med. 1996. 183: 1001-1012.
12. Grabbe, S. and Schwarz, T., Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity. Immunol. Today 1998. 19: 37-44.
13. Thomson, J. A., Troutt, A. B. and Kelso, A., Contact sensitization to oxazolone: involvement of both interferon-γ and interleukin-4 in oxazolone-specific Ig and T cell responses. Immunology 1993. 78: 185-192.
14. Banchereau, J. and Steinman, R. M., Dendritic cells and the control of immunity. Nature 1998. 392: 245-252.
15. Cavani, A., Hackett, C. J., Wilson, K. J., Rothbard, J. B. and Katz, S. I., Characterization of epitopes recognized by hapten-specific CD4+ T cells. J. Immunol. 1995. 154: 1232-1238.
16. Aiba, S. and Katz, S. I., Phenotypic and functional characteristics of in vivo-activated Langerhans cells. J. Immunol. 1990. 145: 2791-2796.
17. Kripke, M. L., Munn, C. G., Jeevan, A., Tang, J. M. and Bucana, C., Evidence that cutaneous antigenpresenting cells migrate to regional lymph nodes during contact sensitization. J. Immunol. 1990. 145: 2833-2838.
18. Dai, R., Grammer, S. F. and Streilein, J. W., Fresh and cultured Langerhans cells display differential capacities to activate hapten-specific T cells. J. Immunol. 1993. 150: 59-66.
19. Larsen, C. P., Ritchie, S. C., Pearson, T. C., Linsley, P. S. and Lowry, R. P., Functional expression of the costimulatory molecule, B7/BB1, on murine dendritic cell populations. J. Exp. Med. 1992. 176: 1215-1220.
20. Larsen, C. P., Ritchie, S. C., Hendrix, R., Linsley, P. S., Hathcock, K. S., Modes, R. J., Lowry, R. P. and Pearson, T. C., Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells. J. Immunol. 1994. 152: 5208-5219.
21. Reiser, H. and Schneeberger, E. E., Expression and function of B7-1 and B7-2 in hapten-induced contact sensitivity. Ear. J. Immunol. 1996. 26: 880-885.
22. Nuriya, S., Yagita, H., Okumura, K. and Azuma, M., The differential role of CD86 and CD80 co-stimulatory molecules in the induction and the effector phases of contact hypersensitivity. Int. Immunol. 1996. 8: 917-926.
23. lnaba, K., Witmer-Pack, M., Inaba, M., Hathcock, K. S., Sakuta, H., Azuma, M., Yagita, H., Okumura, K., Linsley, P. S., Ikehara, S., Muramatsu, S., Modes, R. and Steinman, R., Tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. J. Exp. Med. 1994. 180: 1849-1980.
24. Kawamura, T. and Furue, M., Comparative analysis of B7-1 and B7-2 expression in Langerhans cells: differential regulation by T helper type 1 and T helper type 2 cytokines. Eur. J. Immunol. 1995. 25: 1913-1917.
25. Borriello, F., Sethna, M. P., Boyd, S. D., Schweitzer, A. N., Tivol, E. A., Jacoby, D., Strom, T. B., Simpson, E. M., Freeman, G. I. and Sharpe, A. H., B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. Immunity 1997. 6: 303-313.
26. Tang, A., Judge, T. A., Nickoloff, B. J. and Turka, L. A., Suppression of murine allergic contact dermatitis by CTLA4Ig. Tolerance induction of Th2 responses requires additional blockade of CD40-ligand. J. Immunol. 1996. 157: 117-125.
27. Kondo, S., Kooshesh, F., Wnag, B., Fujisawa, H. and Sauder, D., Contribution of the CD28 molecule to allergic and irritant skin reactions in CD28-/-mice. J. Immunol. 1996. 157: 4822-4829.
28. Hathcock, K. S., Laszlo, G., Pucillo, C., Linsley, P. and Hodes, R. J., Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. J. Exp. Med. 1994. 180: 631-640.
29. Han, S., Hathcock, K., Zheng, B., Kepler, T. B., Hodes, R. and Kelsoe, G., Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. J. Immunol. 1995. 155: 556-567.
30. Kuchroo, V. K., Das, M. P., Brown, J. A., Ranger, A. M., Zamvil, S. S., Sobel, R. A., Weiner, H. L., Nabavi, N. and Glimcher, L. H., B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 development pathways: application to autoimmune disease therapy. Cell 1995. 80: 707-718.
31. Thompson, C. B., Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation? Cell 1995. 81: 979-982.
32. Schweitzer, A. N., Borriello, F., Wong, R. C., Abbas, A. K. and Sharpe, A. H-, Role of costimulators in T cell differentiation: studies using antigen-presenting cells lacking expression of CD80 or CD86. J. Immunol. 1997. 158: 2713-2722.