New contributions to clinical hypertension from molecular biology

Current Opinion in Cardiology

Volumn 13, Issue 5, 1998, Pages 312-316

  Krieger, Jose E ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT;

ENVIRONMENTAL FACTOR; ESSENTIAL HYPERTENSION; HUMAN; MOLECULAR GENETICS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW;

EID: 0031736544     PISSN: 02684705     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001573-199809000-00004     Document Type: Review

References (50)

1. Guyton AC: Blood pressure control: special role of the kidneys and body fluids. Science 1991, 252:1813-1816.
2. Dzau VJ, Krieger JE, Hutchinson H: Molecular mechanisms in hypertension. In Molecular Cardiovascular Medicine. Edited by Haber E. New York: Scientific American; 1995:225-241.
3. Brown MJ: The causes of essential hypertension. Br J Clin Pharmacol 1996, 42:21-27.
4. Ward R: Familial aggregation and genetic epidemiology of blood pressure In Hypertension: Pathophysiology, Diagnosis and Management, edn 2. Edited by Laragh JH, Brenner BM. New York: Raven Press; 1995:67-88.
5. Lander ES: The new genomics: global views of biology. Science 1996, 274:536-539. This paper presents in perspective the Human Genome Project and its implications for understanding biology.
6. Chee M, Yang R, Hubbell E, Berno A, Huang XC, Ster D, et al.: Accessing genetic information with high-density DNA arrays. Science 1996, 274:610-614.
7. Schena M, Shalon D, Davis RW, Brown PO: Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995, 270:467-470.
8. DeRisi J, Penland L, Brown PO, Bittner ML, Meltzer PS, Ray M, et al.: Use of a cDNA microarray to analyze gene expression patterns in human cancer. Nat Genet 1996, 14:456-460.
9. Lockart D, Dong H, Byrne MC, Follettie MT, Gallo MV, Chee MS, et al.: Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat Biotechnol 1996, 14:1675-1680.
10. Velculescu VE, Zhang L, Vogelstein B, Kinzler KW: Serial analysis of gene expression. Science 1995, 270:484-487.
11. Strachan T, Abitbol M, Davidson D, Beckmann JS: A new dimension for the human genome project: towards comprehensive expression maps. Nat Genet 1997, 16:126-132. A comprehensive discussion of the progress of the Human Genome Project and its future goals, including the transition from deciphering structure to function.
12. Jacob HJ, Krieger JE, Dzau VJ, Lander ES: Genetic dissection of hypertension in experimental animal models. In Molecular Genetics and Gene Therapy of Cardiovascular Diseases. Edited by Mockrin SC. New York: Marcel Dekker, Inc; 1996:293-319.
13. Smithies O, Kim H-S: Targeted duplication and disruption for analyzing quantitative genetic traits in mice. Proc Natl Acad Sci U S A 1994, 91:3612-3615.
14. Gassman M, Hennet T: From genetically altered mice to integrative physiology. News Physiol Sci 1998, 13:53-57. This paper presents some of the technology used to develop genetically modified animals. This paper presents some of the technology used to develop genetically modified animals.
15. Lifton RP: Molecular genetics of human blood pressure variation. Science 1996, 272:676-680. The molecular mechanisms underlying the cause of rare monogenic forms of hypertension are described.
16. Lifton RP, Dluhy RG, Powers M, Rich GM, Cook S, Ulick S, Lalouel JM: A chimaeric 11β-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature 1992, 355:262-265.
17. Pascoe L, Curnow KM, Slutsker L, Connell JMC, Speiser PW, New MI, White P: Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2. Proc Natl Acad Sci U S A 1992, 89:8327-8331.
18. Yiu VWY, Dluhy RP, Lifton RP, Guay-Woodtord LM: Low peripheral plasma renin activity as a critical marker m pediatric hypertension. Pediatr Nephrol 1997, 11:343-346. This paper illustrates the application of recently developed technology to the improvement of medical practice.
19. Shimkets RA, Warnock DG, Bositis CM, Nelson-Williams C, Hansson JH, Schambelan M, et al.: Liddle's syndrome: heritable human hypertension caused by mutation in the β subunit of the epithelial sodium channel. Cell 1994, 79:407-414.
20. Schild L, Canessa CM, Shimlets RA, Gaitschi I, Lifton RP, Rossier BC: A mutation in the epithelial sodium channel activity in Xenopus laevis oocyte expression system. Proc Natl Acad Sci U S A 1995, 92:56699-56703.
21. Hansson JH, Nelson-Williams C, Suzuki H, Schild L, Shimkets RA, Lu Y, et al.: Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle's syndrome. Nat Genet 1995, 11:76-80.
22. Hansson JH, Schild L, Lu Y, Wilson TA, Gautschi I, Shimkets RA, et al.: A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity. Proc Natl Acad Sci U S A 1995, 92:11495-11499.
23. Bubien JK, Ismailov II, Berdiev BK, Cornwell T, Lifton RP, Fuller CM, et al.: Liddle's disease: abnormal regulation of amiloride-sensitive Na+ channels by beta-subunit mutation. Am J Physiol 1996, 39:C208-C213.
24. Jeunemaitre X, Bassilana F, Prsu A, Dumont C, Champigny G, Lazdunski M, et al.: Genotype-phenotype analysis of a newly discovered family with Liddle's syndrome. J Hypertens 1997, 15:1091-1100.
25. Grunder S, Rossier BC: A reappraisal of aldosterone effects on the kidney: new insights provided by epithelial sodium channel cloning. Curr Opin Nephrol Hypertens 1997, 6:35-39.
26. Curnow K, Slutsker L, Vitek J, Cole J, Speiser PW, New MI, et al.: Mutations in the CYP11B1 gene causing congenital adrenal hyperplasia and hypertension cluster in exons 6, 7 and 8. Proc Natl Acad Sci U S A 1993, 90:4552-4556.
27. Albinston AL, Obeyesekere VR, Smith RE, Krozowski ZS: Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type II enzyme. Mol Cell Endocrinol 1994, 105:11-17.
28. Mune T, Rogerson FM, Nikkila H, Agarwal AL, White PC: Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase. Nat Genet 1995, 10:394-399.
29. Wilson RC, Krozowski ZS, Li K, Obeyesekere VR, Razzaghy-Azar M, Harbison MD, et al.: A mutation in HSD11beta2 gene in a family with apparent mineralocorticoid excess. J Clin Endocrinol Metab 1995, 80:2263-2266.
30. Li A, Li KXZ, Marui S, Krozowski ZS, Batista MC, Whorwood CB, et al.: Apparent mineralocorticoid excess in a Brazilian kindred: hypertension in the heterozygote state. J Hypertens 1997, 15:1397-1402. Description of a novel mutation in the 11β-hydroxysteroid dehydrogenase gene and the expression of the phenotype in the heterozygote state.
31. Schork NJ, Chakravarti A: A nonmathematical overview of modern gene mapping techniques applied to human diseases. In Molecular Genetics and Gene Therapy of Cardiovascular Diseases. Edited by Mockrin SC. New York: Marcel Dekker, Inc.; 1996:79-109.
32. Rish N, Zhang H: Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 1995, 268:1584-1589.
33. Corvol P, Soubrier F, Jeunemaitre X: Molecular genetics of the renin-angiotensin-aldosterone system in human hypertension. Curr Opin Endocrinol Diabetes 1996, 2:266-275.
34. Jeunemaitre X, Soubrier F, Kotelevtsev YV, Lifton RP, Williams CS, Charru A, et al.: Molecular basis of human hypertension: role of angiotensinogen. Cell 1992, 71:169-180.
35. Kim HS, Krege JH, Kluckman KD, Hagaman JR, Hodgin JB, Best CF, et al.: Genetic control of blood pressure and the angiotensin locus. Proc Natl Acad Sci U S A 1995, 92:2735-2739.
36. Caulfeld M, Lavender P, Farral M, Munroe P, Lawson M, Turner P, Clark AJL: Linkage of the angiotensinogen gene to essential hypertension. N Engl J Med 1994, 330:1629-1633.
37. Caulfeld M, Lavender P, Newell-Price J, Farral M, Kamadar S, Daniel H, et al.: Linkage of the AGT gene locus to human essential hypertension in African Caribbeans. J Clin Invest 1995, 96:687-692.
38. Tiret L, Ricard S, Poirier P, Arveiler D, Cambou JP, Luc G, et al.: Genetic variation at the angiotensinogen locus in relation to high blood pressure and myocardial infarction: the ECTIM study. J Hypertens 1995, 13:311-317.
39. Rotini C, Cooper R, Ogunbiyi O, Morrison L, Ladipo M, Tewksbury D, Ward R: Hypertension, serum angiotensinogen, and molecular variants of the angiotensinogen gene among Nigerians. Circulation 1997, 95:2348-2350.
40. Corvol P, Jeunemaitre X: Molecular genetics of human hypertension: role of angiotensinogen. Endocr Rev 1997, 18:662-677. Comprehensive review on the biology of angiotensinogen and its gene variants.
41. Niu T, Xu X, Rogus J, Zhou Y, Chen C, Yang J, et al.: Angiotensinogen gene and hypertension in Chinese. J Clin Invest 1998, 101:188-194.
42. Atwood LD, Kammerer CM, Samollow PB, Hixson JE, Shade RE, MacCluer JW: Linkage of essential hypertension to angiotensinog locus in Mexican Americans. Hypertension 1997, 30(part 1):326-330.
43. Sato N, Katsuya T, Rakugi H, Takami S, Nakata Y, Miki T, et al.: Association of variants in critical core promoter element of angiotensinogen gene with increased risk of essential hypertension in Japanese. Hypertension 1997, 30(part 1):321-325.
44. Kunz R, Reinhold K, Beige J, Distler A, Sharma AM: Association between the angiotensinogen 235T-variant and essential hypertension in whites: a systematic review and methodological appraisal. Hypertension 1997, 30:1331-1337. This paper discusses important considerations for molecular genetic studies.
45. Brand E, Chatelain N, Keavney B, Caulfield M, Citterio L, Connell J, et al.: Evaluation of angiotensinogen locus in human essential hypertension: a European study. Hypertension 1998, 31:725-729. Large study evaluating the role of the angiotensinogen locus as a susceptibility gene for essential hypertension.
46. Beige J, Zilch O, Hohenbleicher H, Ringel J, Kunz R, Distler A, Sharma AM: Genetic variants of the renin-angiotensin system and ambulatory blood pressure in essential hypertension. J Hypertens 1997, 15:503-508.
47. Julier C, Delépine M, Keavney B, Terwilliger J, Davis S, Weeks DE, et al.: Genetic susceptibility for human familial essential hypertension in a region of homology with blood pressure linkage on rat chromosome 10. Hum Mol Genet 1997, 6:2077-2085. This paper illustrates an attempt to follow through human studies a hypothesis originated from experimental evidence indicating that a specific chromosomal region harbors a gene responsible for hypertension.
48. 2-adrenergic receptor locus. Hypertension 1997, 29:918-922
49. 2-adrenoceptor. Hypertension 1997, 30:773-776.
50. Siffert W, Rosskopf D, Siffert G, Busch S, Moritz A, Erbel R, et al.: Association of human G-protein β3 subunit variant with hypertension. Nat Genet 1998, 18:45-48.