17-β-Estradiol upregulates the stress response in candida albicans: Implications for microbial virulence

Infectious Diseases in Obstetrics and Gynecology

Volumn 6, Issue 4, 1998, Pages 176-181

  O'Connor, C ^a   Essmann, M ^b   Larsen, B ^b  

^a DRAKE UNIVERSITY   (United States)

^b DES MOINES UNIVERSITY   (United States)

Author keywords

17 estradiol; Candida albicans; Global regulation; Heat shock proteins

Indexed keywords

ESTRADIOL; MENADIONE; VIRULENCE FACTOR;

BACTERIAL VIRULENCE; CANDIDA ALBICANS; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; HEAT STRESS; HORMONAL REGULATION; INFECTION RISK; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

CANDIDA ALBICANS; CYTOPLASM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESTRADIOL; FEMALE; FUNGAL PROTEINS; HEAT; HUMANS; OXIDATIVE STRESS; VITAMIN K;

EID: 0031734521     PISSN: 10647449     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-0997(1998)6:4<176::AID-IDOG7>3.0.CO;2-V     Document Type: Conference Paper

References (18)

1. Larsen B: Virulence attributes of low-virulence organisms. Infect Dis Obstet Gynecol 2:95-104, 1994.
2. Larsen B: Normal genital microflora. In Keith LG, Berger GS, Edelman DA (eds): Infections in Reproductive Health. Vol 1. Common Infections. Hingham, MA: MTP Press Limited, pp 3-32, 1985.
3. Lathigra RB, Butcher PD, Garbe TR, Young DB: Heat shock proteins as virulence factors of pathogens. Curr Topics Microbiol Immunol 167:125-140, 1991.
4. Gow NAR: Growth and guidance of the fungal hypha. Microbiol 140:3193-3205, 1994.
5. Kinsman OS, Pitblado K, Coulson CJ: Effect of mammalian steroid hormones and luteinizing hormone on the germination of Candida albicans and implications for vaginal candidosis. Mycoses 31(12):617-626, 1988.
6. Hsiu-Jung L, Köhler JR, DiDomenico B, Loebenberg D, Cacciapuoti A, Fink GR: Nonfilamentous C. albicans mutants are avirulent. Cell 90:939-949, 1997.
7. Köhler JR, Fink GR: Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development. Proc Natl Acad Sci USA 93:13223-13228, 1996.
8. Leberer E, Harcus D, Broadbent ID, et al.: Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans. Proc Natl Acad Sci USA 93:13217-13222, 1996.
9. Hodgetts S, Matthews R, Morrissey G, Mitsutake K, Piper P, Burnie J: Over-expression of Saccharomyces cerevisiae hsp90 enhances the virulence of this yeast in mice. FEMS Immunol Med Microbiol 16:229-234, 1996.
10. White S, Larsen B: Candida albicans morphogenesis is influenced by estrogen. Cell Mol Life Sci 53:744-749, 1997.
11. Gujjar PB, Finucane M, Larsen B: The effect of estradiol on Candida albicans growth. Annals Clin Lab Sci 27(2):151-156, 1997.
12. Larsen B, Galask RP: Influence of estrogen and normal flora on vaginal candidiasis in the rat. J Reprod Med 29(12):863-868, 1984.
13. Glover DD, Larsen B: Longitudinal investigation of Candida vaginitis in pregnancy: role of superimposed antibiotic use. Obstet Gynecol 91(1):115-118, 1998.
14. Nicolet CM, Craig EA: Inducing and assaying heat-shock response in Saccharomyces cerevisiae. In Lorimer GH, Baldwin TO (eds): Methods in Enzymology. Vol 194. New York: Academic Press, Inc., pp 710-717, 1991.
15. Bromuro C, La Valle R, Sandini S, et al.: A 70-kilodalton recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis. Infect Immun 66(5):2154-2162, 1998.
16. Matthews R, Hodgetts S, Burnie J: Preliminary assessment of a human recombinant antibody fragment to hsp90 in murine invasive candidiasis. J Infect Dis 171: 1668-1671, 1995.
17. Matthews RC, Burnie JP: Cloning of a DNA sequence encoding a major fragment of the 47 kilodalton stress protein homologue of Candida albicans. FEMS Microbiol Lett 60:25-30, 1989.
18. Davidson JF, Whyte B, Bissinger PH, Schiestl RH: Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 93: 5116-5121, 1996.