A proportion of proteinase 3 (PR3)-specific anti-neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N-terminal activation dipeptide

Clinical and Experimental Immunology

Volumn 114, Issue 2, 1998, Pages 320-326

  Sun, J ^a   Fass, D N ^a   Viss, M A ^a   Hummel, A M ^a   Tang, H ^a   Homburger, H A ^a   Specks, U ^a  

^a MAYO CLINIC   (United States)

Author keywords

Anti neutrophil; Cytoplasmic antibodies; N terminal propeptide; Recombinant proteinase 3; Target antigen

Indexed keywords

EPITOPE; MYELOBLASTIN; NEUTROPHIL CYTOPLASMIC ANTIBODY;

AMINO TERMINAL SEQUENCE; ANTIGEN RECOGNITION; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; VASCULITIS; WEGENER GRANULOMATOSIS;

ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; CELL LINE; CELL LINE, TRANSFORMED; DIPEPTIDES; GENE EXPRESSION; HUMANS; MYELOBLASTIN; RECOMBINANT FUSION PROTEINS; SERINE ENDOPEPTIDASES;

EID: 0031731699     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1998.00730.x     Document Type: Article

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