메뉴 건너뛰기




Volumn 139, Issue 6, 1998, Pages 2676-2684

Desensitization of the β-adrenergic response in human brown adipocytes

Author keywords

[No Author keywords available]

Indexed keywords

ISOPRENALINE;

EID: 0031731568     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.6.6050     Document Type: Article
Times cited : (42)

References (41)
  • 1
    • 0027287413 scopus 로고
    • Fat cell adrenergic receptors and the control of white and brown fat cell function
    • Lafontan M, Berlan M 1993 Fat cell adrenergic receptors and the control of white and brown fat cell function. J Lipid Res 34:1057-1091
    • (1993) J Lipid Res , vol.34 , pp. 1057-1091
    • Lafontan, M.1    Berlan, M.2
  • 2
    • 0028988313 scopus 로고
    • Regulation of β3-adrenoceptor expression in white fat cells
    • Langin D, Tavernier G, Lafontan M 1995 Regulation of β3-adrenoceptor expression in white fat cells. Fund Clin Pharmacol 9:97-106
    • (1995) Fund Clin Pharmacol , vol.9 , pp. 97-106
    • Langin, D.1    Tavernier, G.2    Lafontan, M.3
  • 3
    • 0025260137 scopus 로고
    • Brown adipose tissue thermogenesis: Inter-disciplinary studies
    • Himms-Hagen J 1990 Brown adipose tissue thermogenesis: inter-disciplinary studies. FASEB J 4:2890-2898
    • (1990) FASEB J , vol.4 , pp. 2890-2898
    • Himms-Hagen, J.1
  • 6
    • 0024784641 scopus 로고
    • Thermogenesis and brown fat: Relevance to human obesity
    • Stock MJ 1989 Thermogenesis and brown fat: relevance to human obesity. Infusiontherapie 16:282-284
    • (1989) Infusiontherapie , vol.16 , pp. 282-284
    • Stock, M.J.1
  • 8
    • 0029865228 scopus 로고    scopus 로고
    • Prospects for β3-adrenoceptor agonists in the treatment of obesity and diabetes
    • Arch JR, Wilson S 1996 Prospects for β3-adrenoceptor agonists in the treatment of obesity and diabetes. Int J Obes Relat Metab Disord 20:191-199
    • (1996) Int J Obes Relat Metab Disord , vol.20 , pp. 191-199
    • Arch, J.R.1    Wilson, S.2
  • 9
    • 0030928350 scopus 로고    scopus 로고
    • Structure and function of the β3-adrenergic receptor
    • Strosberg AD 1997 Structure and function of the β3-adrenergic receptor. Annu Rev Pharmacol Toxicol 37:421-450
    • (1997) Annu Rev Pharmacol Toxicol , vol.37 , pp. 421-450
    • Strosberg, A.D.1
  • 10
    • 0028518565 scopus 로고
    • Coexisting β-adrenoceptor subtypes: Significance for thermogenic process in brown fat cells
    • Zhao J, Unelius L, Bengtsson T, Cannon B, Nedergaard J 1994 Coexisting β-adrenoceptor subtypes: significance for thermogenic process in brown fat cells. Am J Physiol 267:C969-C979
    • (1994) Am J Physiol , vol.267
    • Zhao, J.1    Unelius, L.2    Bengtsson, T.3    Cannon, B.4    Nedergaard, J.5
  • 13
    • 0027418423 scopus 로고
    • Structural basis for receptor subtype-specific regulation revealed by a chimeric β3/β2-adrenergic receptor
    • Liggett SB, Freedman NJ, Schwinn DA, Lefkowitz RJ 1993 Structural basis for receptor subtype-specific regulation revealed by a chimeric β3/β2-adrenergic receptor. Proc Natl Acad Sci USA 90:3665-3669
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3665-3669
    • Liggett, S.B.1    Freedman, N.J.2    Schwinn, D.A.3    Lefkowitz, R.J.4
  • 14
    • 0026755271 scopus 로고
    • Effects of agonist exposure on the coupling of β1 and β3 adrenergic receptors to adenylyl cyclase in isolated adipocytes
    • Granneman JG 1992 Effects of agonist exposure on the coupling of β1 and β3 adrenergic receptors to adenylyl cyclase in isolated adipocytes. J Pharmacol Exp Ther 261:638-642
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 638-642
    • Granneman, J.G.1
  • 15
    • 0027494518 scopus 로고
    • Desensitization of β1- and β2- but not β3-adrenoceptor-mediated lipolytic responses of adipocytes after long-term norepinephrine infusion
    • Carpéné C, Galitzky J, Collon P, Esclapez F, Dauzats M, Lafontan M 1993 Desensitization of β1-and β2-but not β3-adrenoceptor-mediated lipolytic responses of adipocytes after long-term norepinephrine infusion. J Pharmacol Exp Ther 265:237-247
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 237-247
    • Carpéné, C.1    Galitzky, J.2    Collon, P.3    Esclapez, F.4    Dauzats, M.5    Lafontan, M.6
  • 16
    • 0029132152 scopus 로고
    • Contribution of β3-adrenoceptor activation to ephedrine-induced thermogenesis in humans
    • Liu YL, Toubro S, Astrup A, Stock MJ 1995 Contribution of β3-adrenoceptor activation to ephedrine-induced thermogenesis in humans. Int J Obes Relat Metab Disord 19:678-685
    • (1995) Int J Obes Relat Metab Disord , vol.19 , pp. 678-685
    • Liu, Y.L.1    Toubro, S.2    Astrup, A.3    Stock, M.J.4
  • 18
    • 0030789490 scopus 로고    scopus 로고
    • The biochemical effect of the naturally occurring Trp64Arg mutation on human β3-adrenoceptor activity
    • Pietri-Rouxel F, Manning B, Gros J, Strosberg AD 1997 The biochemical effect of the naturally occurring Trp64Arg mutation on human β3-adrenoceptor activity. Eur J Biochem 247:1174-1179
    • (1997) Eur J Biochem , vol.247 , pp. 1174-1179
    • Pietri-Rouxel, F.1    Manning, B.2    Gros, J.3    Strosberg, A.D.4
  • 19
    • 0029670099 scopus 로고    scopus 로고
    • In situ assessment of the role of the β-1, β-2 and β-3-adrenoceptors in the control of lipolysis and nutritive blood flow in human subcutaneous adipose tissue
    • Barbe P, Millet L, Galitzky J, Lafontan M, Berlan M 1996 In situ assessment of the role of the β-1, β-2 and β-3-adrenoceptors in the control of lipolysis and nutritive blood flow in human subcutaneous adipose tissue. Br J Pharmacol 117:907-913
    • (1996) Br J Pharmacol , vol.117 , pp. 907-913
    • Barbe, P.1    Millet, L.2    Galitzky, J.3    Lafontan, M.4    Berlan, M.5
  • 21
    • 0027424566 scopus 로고
    • Physiological desensitization of beta(3)-adrenergic responses in brown fat cells: Involvement of a postreceptor process
    • Unelius L, Bronnikov G, Mohell N, Nedergaard J 1993 Physiological desensitization of beta(3)-adrenergic responses in brown fat cells: involvement of a postreceptor process. Am J Physiol 265:C1340-C1348
    • (1993) Am J Physiol , vol.265
    • Unelius, L.1    Bronnikov, G.2    Mohell, N.3    Nedergaard, J.4
  • 22
    • 0027331006 scopus 로고
    • Attenuation of Gsα coupling efficiency in brown-adipose-tissue plasma membranes from cold-acclimated hamsters
    • Svoboda P, Unelius L, Cannon B, Nedergaard J 1993 Attenuation of Gsα coupling efficiency in brown-adipose-tissue plasma membranes from cold-acclimated hamsters. Biochem J 295:655-661
    • (1993) Biochem J , vol.295 , pp. 655-661
    • Svoboda, P.1    Unelius, L.2    Cannon, B.3    Nedergaard, J.4
  • 23
    • 0028987432 scopus 로고
    • Desensitization of β-adrenergic responses in adipocytes involves receptor subtypes and cAMP phosphodiesterase
    • Bousquet-Mélou A, Galitzky J, Moreno CM, Berlan M, Lafontan M 1995 Desensitization of β-adrenergic responses in adipocytes involves receptor subtypes and cAMP phosphodiesterase. Eur J Pharmacol 289:235-247
    • (1995) Eur J Pharmacol , vol.289 , pp. 235-247
    • Bousquet-Mélou, A.1    Galitzky, J.2    Moreno, C.M.3    Berlan, M.4    Lafontan, M.5
  • 25
    • 0024440502 scopus 로고
    • Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium
    • Hauner H, Entenmann G, Wabitsch M, Gaillard D, Ailhaud G, Negrel R, Pfeiffer EF 1989 Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium. J Clin Invest 84:1663-1670
    • (1989) J Clin Invest , vol.84 , pp. 1663-1670
    • Hauner, H.1    Entenmann, G.2    Wabitsch, M.3    Gaillard, D.4    Ailhaud, G.5    Negrel, R.6    Pfeiffer, E.F.7
  • 26
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 27
    • 0003374946 scopus 로고
    • BAT in humans
    • Trayhurn P, Nicholls DG (eds) Edward Arnold, London
    • Lean M, James WPT 1986 BAT in humans. In: Trayhurn P, Nicholls DG (eds) Brown Adipose Tissue. Edward Arnold, London, pp 338-365
    • (1986) Brown Adipose Tissue , pp. 338-365
    • Lean, M.1    James, W.P.T.2
  • 29
    • 0025940707 scopus 로고
    • Molecular characterization of the mouse β3-adrenergic receptor: Relationship with the atypical receptor of adipocytes
    • Nahmias C, Blin N, Elalouf J-M, Mattei MG, Strosberg AD, Emorine LJ 1991 Molecular characterization of the mouse β3-adrenergic receptor: relationship with the atypical receptor of adipocytes. EMBO J 10:3721-3727
    • (1991) EMBO J , vol.10 , pp. 3721-3727
    • Nahmias, C.1    Blin, N.2    Elalouf, J.-M.3    Mattei, M.G.4    Strosberg, A.D.5    Emorine, L.J.6
  • 30
    • 0019838290 scopus 로고
    • Recovery of β-adrenergic receptors following long term exposure of astrocytoma cells to catecholamine: Role of protein synthesis
    • Doss RC, Perkins JP, Harden TK 1981 Recovery of β-adrenergic receptors following long term exposure of astrocytoma cells to catecholamine: role of protein synthesis. J Biol Chem 256:12281-12286
    • (1981) J Biol Chem , vol.256 , pp. 12281-12286
    • Doss, R.C.1    Perkins, J.P.2    Harden, T.K.3
  • 31
    • 0027308299 scopus 로고
    • Correlation of β3-adrenoceptor-induced activation of cyclic AMP-dependent protein kinase with activation of lipolysis in rat white adipocytes
    • Murphy GJ, Kirkham DM, Cawthorne MA, Young P 1993 Correlation of β3-adrenoceptor-induced activation of cyclic AMP-dependent protein kinase with activation of lipolysis in rat white adipocytes. Biochem Pharmacol 46:575-581
    • (1993) Biochem Pharmacol , vol.46 , pp. 575-581
    • Murphy, G.J.1    Kirkham, D.M.2    Cawthorne, M.A.3    Young, P.4
  • 32
    • 0028969547 scopus 로고
    • Functional effects of long-term activation on human β2- and β3-adrenoceptor signalling
    • Nantel F, Bouvier M, Strosberg AD, Marullo S 1995 Functional effects of long-term activation on human β2-and β3-adrenoceptor signalling. Br J Pharmacol 114:1045-1051
    • (1995) Br J Pharmacol , vol.114 , pp. 1045-1051
    • Nantel, F.1    Bouvier, M.2    Strosberg, A.D.3    Marullo, S.4
  • 34
    • 0027761394 scopus 로고
    • Structural and conformational features determining selective signal transduction in the β3-adrenergic receptor
    • Blin N, Camoin L, Maigret B, Strosberg AD 1993 Structural and conformational features determining selective signal transduction in the β3-adrenergic receptor. Mol Pharmacol 44:1094-1104
    • (1993) Mol Pharmacol , vol.44 , pp. 1094-1104
    • Blin, N.1    Camoin, L.2    Maigret, B.3    Strosberg, A.D.4
  • 35
    • 0030909051 scopus 로고    scopus 로고
    • Four β-adrenoceptor subtypes in the mammalian heart
    • Kaumann AJ 1997 Four β-adrenoceptor subtypes in the mammalian heart. Trends Pharmacol Sci 18:70-76
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 70-76
    • Kaumann, A.J.1
  • 36
    • 0030734704 scopus 로고    scopus 로고
    • Lipolytic effects of conventional β3-adrenoceptor agonists and of CGP 12,177 in rat and human fat cells: Preliminary pharmacological evidence for a putative β4-adrenoceptor
    • Galitzky J, Langin D, Verwaerde P, Montastruc JL, Lafontan M, Berlan M 1997 Lipolytic effects of conventional β3-adrenoceptor agonists and of CGP 12,177 in rat and human fat cells: preliminary pharmacological evidence for a putative β4-adrenoceptor. Br J Pharmacol 122:1244-1250
    • (1997) Br J Pharmacol , vol.122 , pp. 1244-1250
    • Galitzky, J.1    Langin, D.2    Verwaerde, P.3    Montastruc, J.L.4    Lafontan, M.5    Berlan, M.6
  • 37
    • 0029816574 scopus 로고    scopus 로고
    • Evidence from in vitro differentiating cells that adrenoceptor agonists can increase uncoupling protein mRNA level in adipocytes of adult humans: An RT-PCR study
    • Champigny O, Ricquier D 1996 Evidence from in vitro differentiating cells that adrenoceptor agonists can increase uncoupling protein mRNA level in adipocytes of adult humans: an RT-PCR study. J Lipid Res 37:1907-1914
    • (1996) J Lipid Res , vol.37 , pp. 1907-1914
    • Champigny, O.1    Ricquier, D.2
  • 38
    • 0030299965 scopus 로고    scopus 로고
    • Down-regulation of β3 adrenoceptor gene expression in brown fat cells is transient and recovery is dependent upon a short-lived protein factor
    • Bengtsson T, Redegren K, Strosberg AD, Nedergaard J, Cannon B 1996 Down-regulation of β3 adrenoceptor gene expression in brown fat cells is transient and recovery is dependent upon a short-lived protein factor. J Biol Chem 271:33366-33375
    • (1996) J Biol Chem , vol.271 , pp. 33366-33375
    • Bengtsson, T.1    Redegren, K.2    Strosberg, A.D.3    Nedergaard, J.4    Cannon, B.5
  • 39
    • 0023713595 scopus 로고
    • Mechanism for desensitization of β-adrenergic receptor-stimulated lipolysis in adipocytes from rats harbouring pheochromocytoma
    • Prokocimer PG, Maze M, Vickery RG, Hoffmann BB 1988 Mechanism for desensitization of β-adrenergic receptor-stimulated lipolysis in adipocytes from rats harbouring pheochromocytoma. Endocrinology 123:528-533
    • (1988) Endocrinology , vol.123 , pp. 528-533
    • Prokocimer, P.G.1    Maze, M.2    Vickery, R.G.3    Hoffmann, B.B.4
  • 40
    • 0027375964 scopus 로고
    • Molecular mechanisms of membrane receptor desensitization
    • Lohse MJ 1993 Molecular mechanisms of membrane receptor desensitization. Biochim Biophys Acta 1179:171-188
    • (1993) Biochim Biophys Acta , vol.1179 , pp. 171-188
    • Lohse, M.J.1
  • 41
    • 16944366762 scopus 로고    scopus 로고
    • Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and β-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms
    • Moule SK, Welsh GI, Edgell NJ, Foulstone EJ, Proud CG, Denton RM 1997 Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and β-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms. J Biol Chem 272: 7713-7719
    • (1997) J Biol Chem , vol.272 , pp. 7713-7719
    • Moule, S.K.1    Welsh, G.I.2    Edgell, N.J.3    Foulstone, E.J.4    Proud, C.G.5    Denton, R.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.