The in-vitro generation of dendritic cells from blast cells in acute leukaemia

British Journal of Haematology

Volumn 103, Issue 3, 1998, Pages 763-771

  Robinson, S P ^a   English, N ^a   Jaju, R ^b   Kearney, L ^b   Knight, S C ^a   Reid, C D L ^c  

^a NORTHWICK PARK INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c ST MARK S HOSPITAL   (United Kingdom)

Author keywords

Acute leukaemia; Anti tumour immunity; Antigen presentation; Dendritic cells; Differentiation

Indexed keywords

B7 ANTIGEN; CD19 ANTIGEN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; CELL ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; INTERLEUKIN 4; STEM CELL FACTOR; T6 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE LEUKEMIA; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; BLAST CELL; CELL CULTURE; CELL GROWTH; CELL STRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; IN VITRO STUDY; MIXED LYMPHOCYTE REACTION; MONONUCLEAR CELL; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL;

ACUTE DISEASE; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CELL TRANSFORMATION, NEOPLASTIC; DENDRITIC CELLS; HUMANS; IMMUNOPHENOTYPING; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA; TUMOR CELLS, CULTURED;

EID: 0031729615     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Bonnet, D. & Dick, J.E. (1997) Human acute myeloid leukaemia is organised as a hierarchy that originates from a primitive haemopoietic cell. Nature Medicine, 3, 730-737.
2. Buckle, V.J. & Rack, K. (1993) Fluorescent in situ hybridisation. Human Genetic Disease Analysis: a Practical Approach (ed. by K. E. Davies), p. 59, IRL Press, Oxford.
3. Carbonell, E., Swansbury, J., Min, T., Matutes, E., Farahat, N., Buccheri, V. Morilla, R., Seeker-Walker, L. & Catovsky, D. (1996) Cytogenetic findings in acute biphenotypic leukemia. Leukemia, 10, 1283-1287.
4. Cardoso, A.A., Seamon, M.J., Afonso, H.M., Ghia, P., Boussitiotis, V.A., Freeman, G.J., Gribben, J.G., Sallan, S.E. & Nadler, L.M. (1997) Ex vivo generation of human anti-pre-B leukemia specific autologous cytolytic T cells. Blood, 90, 549-561.
5. Caux, C., Dezutter-Dambuyant, C., Schmitt, D. & Banchereau, J. (1992) GM-CSF and TNF-α co-operate in the generation of dendritic Langerhans cells. Nature, 360, 258-261.
6. Choudhury, A., Gajewski, J.L., Liang, J.C., Popat, U., Claxton, D.F., Kliche K-O., Andreef, M. & Champlin, R. (1997) Use of leukemic dendritic cells for the generation of antileukemic cellular cytotoxicity against Philadelphia chromosome-positive chronic myelogenous leukemia. Blood, 89, 1133-1142.
7. Freudenthal, P.S. & Steinman, R.M. (1990) The distinct surface of human blood dendritic cells, as observed after an improved isolation method. Proceedings of the National Academy of Sciences of the United States of America, 87, 7698-7702.
8. Grabbe, S., Beissert, S., Schwarz, T. & Granstein, R.D. (1996) Dendritic cells as initiators of tumour immune responses: a possible strategy for tumour immunotherapy? Immunology Today, 16, 117-121.
9. Hsu, F.J., Benike, C., Fagnoni, F., Liles, T.M., Czerwinski, D., Taidi, B., Engelman, E.G. & Levy, R. (1996) Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nature Medicine, 2, 52-58.
10. Kearney, L., Bower, M., Gibbons, B., Das, S., Chaplin, T., Nacheva, E., Chessells, J.M., Reeves, B., Riley, J.H., Lister, T.A. & Young, B.D. (1992) Chromosome 11q23 translocations in both infant and adult acute leukemias are detected by in situ hybridisation with yeast artificial chromosome. Blood, 80, 1659-1665.
11. Knight, S.C. (1990) Lymphocyte proliferation assays. Lymphocytes: a Practical Approach (ed. by G. G. B. Klaus), p. 189, IRL Press, Oxford.
12. Knight, S.C., Hunt, R., Dore, C. & Medawar, P.B. (1986) Influence of dendritic cells on tumor growth. Proceedings of National Acedamy of Sciences of the United States of America, 82, 4495-4497.
13. Knight, S.C., Mertin, J., Stackpoole, A. & Clark, J. (1983) Induction of immune responses in vivo with small numbers of veiled cells. Proceedings of the National Academy of Sciences of the United States of America, 80, 6032-6035.
14. Knight, S.C. & Stagg, A.J. (1993) Antigen presenting cell types. Current Opinion in Immunology, 5, 374-382.
15. Kolb, H.-J., Schattenberg, A., Goldman, J.M., Hertenstein, B., Jacobsen, N., Arcese, W., Ljungman, P., Ferrant, A., Verdnock, L., Niederwiesser, D., van Rhee, F., Mittermueller, J., de Witte, T., Holler, E. & Ansari, H. (1995) Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. Blood, 86, 2041-2050.
16. Lenschow, D.J., Walunas, T.L. & Bluestone, J.A. (1996) CD28/B7 system of T cell co-stimulation. Annual Review of Immunology, 14, 233-258.
17. Lokhorst, H.M., Schattenberg, A., Cornelissen, J.J., Thomas, L.L.M. & Verdonck, L.F. (1997) Donor leukocyte infusions are effective in relapsed multiple myeloma after allogeneic bone marrow transplantation. Blood, 90, 4206-4211.
18. Mayordomo, J.L., Zorina, T., Storkus, W.J., Zitvogel, L., Celluzzi, C., Falo, L.D., Melief, C.J., Ildstad, S.T., Martin Kast, W., Dele, A.B. & Lotze, M.T. (1995) Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity. Nature Medicine, 1, 1297-1302.
19. Misery, L., Campos, L., Dezutter-Dambuyant, C., Guyotat, D., Treille, D., Schmitt, D. & Thivolet, J. (1992) CD1-reactive leukaemic cells in bone marrow: presence of Langerhans cell marker on leukaemic monocytic cells. European Journal of Haematology, 48, 27-32.
20. Ostrand-Rosenberg, S. (1994) Tumour immunotherapy: the tumour cell as an antigen-presenting cell. Current Opinion in Immunology, 6, 722-727.
21. Reid, C.D., Fryer, P.R., Clifford, C., Kirk, A., Tikerpae, J. & Knight, S.C. (1990) Identification of hematopoietic progenitors of macrophages and dendritic Langerhans cells (DL-CFU) in human bone marrow and peripheral blood. Blood, 76, 1139-1149.
22. + progenitors in human bone marrow. Journal of Immunology, 149, 2681-2688.
23. Salem, M., Delwel, R., Mahmoud, L., Clark, S., Elbasousy, E.M. & Lowenberg, R. (1989) Maturation of human acute myeloid leukaemia in vitro: the response to live recombinant haemopoietic factors in a serum-free system. British Journal of Haematology, 71, 363-370.
24. Santiago-Schwarz, F., Coppock, D.L., Hindenberg, A.A. & Kern, J. (1994) Identification of a malignant counterpart of the monocyte-dendritic cell progenitor in an acute myeloid leukemia. Blood, 84, 3054-3062.
25. Schuler, G. & Steinman, R.M. (1997) Dendritic cells as adjuvants for immune-mediated resistance to tumours. Journal of Experimental Medicine, 186, 1183-1187.
26. Takahashi, K., Miyatani, K., Yanai, H., Jeon, H.J., Fujiwara, K., Yoshino, T., Hayashi, K., Akagi, T., Tsutsui, K. & Mizohuchi, K. (1992) Induction of interdigitating reticulum cell-like differentiation in human monocytic leukaemia cells by conditioned medium from IL-2 stimulated helper T cells. Virchows Archive B: Cell Pathology, 62, 105-113.
27. Westbrook, C.A., Neuman, W.L., McPherson, J., Campurs, S., Wasmuth, J., Plaetke, R. & Williamson, R. (1992) Report of the Second International Workshop on Human Chromosome 5 Mapping. Cytogenetics and Cell Genetics, 61, 225-242.
28. Zhou, L.J. & Tedder, T.F. (1995) Human blood dendritic cells selectively express CD83, a member of the immunoglobulin super-family. Journal of Immunology, 154, 3821-3835.