Influence of receptor number on the stimulation by salmeterol of gene transcription in CHO-K1 cells transfected with the human β2-adrenoceptor

British Journal of Pharmacology

Volumn 125, Issue 4, 1998, Pages 717-726

  McDonnell, J ^a   Latif, M L ^a   Rees, E S ^b   Bevan, N J ^b   Hill, S J ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

2 adrenoceptor; CHO K1 cells; Cyclic AMP; Cyclic AMP response element; Gene transcription; Receptor number; Reporter gene; Salmeterol; Secreted alkaline phosphatase

Indexed keywords

ALKALINE PHOSPHATASE; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; ISOPRENALINE; SALMETEROL;

ANIMAL CELL; ARTICLE; BREATHING MUSCLE; CHO CELL; CONTROLLED STUDY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; REPORTER GENE; SERUM; SMOOTH MUSCLE;

ADRENERGIC BETA-AGONISTS; ALBUTEROL; ALKALINE PHOSPHATASE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; IODOCYANOPINDOLOL; ISOPROTERENOL; RECEPTORS, ADRENERGIC, BETA-2; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0031728307     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702139     Document Type: Article

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