Second degree atrio-ventricular block and cardiotoxicity secondary to envenomation by the scorpion Leiurus quinquestriatus ('yellow scorpion') - An indication for serotherapy?

Human and Experimental Toxicology

Volumn 17, Issue 10, 1998, Pages 541-543

  Shapira, Michael Y ^a   Haviv, Yosef S ^a   Sviri, Sigal ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Anti venin; Bradyarrhythmia; Scorpion envenomation; Troponin I

Indexed keywords

METOCLOPRAMIDE; MORPHINE; SCORPION VENOM; TROPONIN I; VENOM ANTISERUM;

ADULT; ARTICLE; ATRIOVENTRICULAR BLOCK; CARDIOTOXICITY; CASE REPORT; CLINICAL FEATURE; ENVENOMATION; FLUID THERAPY; HUMAN; PRIORITY JOURNAL; SCORPION;

ADULT; ANIMALS; ANTIVENINS; ARACHNIDISM; BRADYCARDIA; CREATINE KINASE; ELECTROCARDIOGRAPHY; HEART; HEART BLOCK; HUMANS; L-LACTATE DEHYDROGENASE; MALE; SCORPION VENOMS; SCORPIONS; TREATMENT OUTCOME; TROPONIN I;

LEIURUS QUINQUESTRIATUS; SCORPIONES;

EID: 0031727225     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/096032798678907928     Document Type: Article

References (14)

1. Gueron M, Margulis G, Sofer S. Echocardiographic and radionuclide angiographic observations following scorpion envenomation by Leiurus Quinquestriatus. Toxicon 1990; 28: 1005-1009.
2. Sofer S, Shahak E, Slonim A, Gueron M. Myocardial injury without heart failure following envenomation by the scorpion Leiurus Quinquestriatus in children. Toxicon 1991; 29: 382-385.
3. Cantor A, Wanderman KL, Ovsyshcher I, Gueron M. Parasympathomimetic action of scorpion venom on the cardiovascular system. Isr J Med Sci 1977; 13: 908-911.
4. Omran MA, Abdel Rahman MS, Nabil ZI. Effect of scorpion Leiurus Quinquestriatus (H&E) venom on rat's heart rate and blood pressure. Toxicol Lett 1992; 61: 111-121.
5. Diaz M, Sepulveda FV. Characterization of Ca(2+)-dependent inwardly rectifying K+ currents in HeLa cells. Pflugers Arch 1995; 430: 168-180.
6. Garcia ML et al. Charybdotoxin and its effects on potassium channels. Am J Physiol. 1995; 269: C1-C10.
7. Borneman J, Hahin R. Purification of protein toxins from Leiurus Quinquestriatus hebraeus that modify Na channels. Toxicon 1993; 31: 1019-1038.
8. DeBin JA, Maggio JE, Strichartz GR. Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion, Am J Physiol 1993; 264: C361-369.
9. Zlotkin E, Gurevitz M, Fowler E, Adams ME. Depressant insect selective neurotoxins from scorpion venom: chemistry, action, and gene cloning. Arch Insect Biochem Physiol. 1993; 22: 55-73.
10. Arie Saadia G, Sofer S, Zlotkin, Shainberg A. Effect of Leiurus Quinquestriatus hebreus venom on calcium and deoxyglucose uptake in cultured cardiac cells. Toxicon 1996; 34: 435-442.
11. Ismail M, Fatani AJ and Dabees TT. Experimental treatment protocols for scorpion envenomation: a review of common therapies and an effect of kallikrein-kinin inhibitors. Toxicon 1992; 30: 1257-1279.
12. Bawaskar HS, Bawaskar PH. Role of atropine in management of cardiovascular manifestations of scorpion envenoming in humans. J Trop Med Hyg 1992; 95: 30-35.
13. Bawaskar HS and Bawaskar PH. Severe envenoming by the Indian red scorpion Mesobuthus tamulus: the use of prazosin therapy. QJM 1996; 89: 701-704.
14. Bawaskar HS, Bawaskar PH. Vasodilators: scorpion envenoming and the heart (an Indian experience). Toxicon 1994; 32: 1031-1040.