Effect of Leiurus quinquestriatus hebreus venom on calcium and deoxyglucose uptake in cultured cardiac cells

Toxicon

Volumn 34, Issue 4, 1996, Pages 435-442

  Arie Saadia, Galit ^a   Sofer, Shaul ^b   Zlotkin, Eli ^c   Shainberg, Asher ^a  

^a BAR ILAN UNIVERSITY   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

LEIURUS QUINQUESTRIATUS; SCORPIONES;

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; DEOXYGLUCOSE; PROPRANOLOL; SCORPION VENOM; BETA ADRENERGIC RECEPTOR; CALCIUM ANTAGONIST; NIFEDIPINE;

ANIMAL; ARTICLE; CELL CULTURE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; FRACTIONATION; GEL CHROMATOGRAPHY; HEART; HEART CONTRACTION; HEART MUSCLE; ION EXCHANGE CHROMATOGRAPHY; METABOLISM; RAT; SARCOPLASMIC RETICULUM; ANIMAL CELL; CALCIUM TRANSPORT; CONTROLLED STUDY; HEART CELL CULTURE; NONHUMAN; PRIORITY JOURNAL;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CELLS, CULTURED; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; DEOXYGLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART; MYOCARDIAL CONTRACTION; MYOCARDIUM; NA(+)-K(+)-EXCHANGING ATPASE; PROPRANOLOL; RATS; SARCOPLASMIC RETICULUM; SCORPION VENOMS;

EID: 0029658936     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/0041-0101(95)00152-2     Document Type: Article

References (25)

1. Bernard, P. and Couraud, F. (1979) Electrophysiological studies on embryonic heart cells in culture. Scorpion toxin as a tool to reveal latent fast sodium channel. Biochim. biophys Acta 553, 154-168.
2. Brik, H., Gamliel, A. and Shainberg, A. (1989) Characterization of sarcoplasmic reticulum in skinned muscle cultures. Biochim. biophys Acta 980, 273-280.
3. Brik, H. and Shainberg, A. (1990) Thyroxine induces transition of red towards white muscle in cultured heart cells. Basic Res. Cardiol. 85, 237-246.
4. Couraud, F., Rochat, H. and Lissitzky, S. (1976) Stimulation of sodium and calcium uptake by scorpion toxin in chick embryo heart cells. Biochim. biophys. Acta 433, 90-100.
5. De Haan, R. L. (1967) Regulation of spontaneous activity and growth of embryonic chick heart cells in tissue culture. Dev. Biol. 16, 216-249.
6. Disatnik, M. H. and Shainberg, A. (1992) Effects of calcium and cablocker D600 on the β-adrenoceptors in myocardial cells in vitro. Biochem. Pharmac. 43, 213-217.
7. Gueron, M., Margolis, G. and Sofer, S. (1990) Echocardiographic and radionuclide angiographic observation following scorpion envenomation by Leiurus quinquestriatus. Toxicon 28, 1005-1009.
8. Gueron, M. and Yarom, R. (1970) Cardiovascular manifestation of severe scorpion sting. Chest 57, 156-162.
9. Hagag, M., Tu, A. T. and El-Asmar, F. (1983) Isolation of Minax toxins from the venom of the scorpion Buthus minax and their metabolic effects. Archs Biochem. Biophys. 220, 459-466.
10. Ismail, M. (1995) The scorpion envenoming syndrome. Toxicon 33, 825-858.
11. Ismail, M., Fatani, A. J. Y. and Dabees, T. T. (1992) Experimental treatment protocols for scorpion envenomation: a review of common therapies and an effect of Kallikrein-Kinin inhibitors. Toxicon 30, 1257-1279.
12. Lytton, J. and MacLennan, D. H. (1992) Sarcoplasmic reticulum. In: The Heart of Cardiovascular System, pp. 1203-1221 (Fozzard, H. A., Ed.). New York: Raven Press.
13. Murthy, K. R. K., Anita, A. G., Dave, B. N. and Billimoria, F. R. (1988) Erythrocyte Na-K-ATPase activity inhibition and increase in red cell fragility in experimental myocarditis produced by Indian red scorpion venom. Indian J. Med. Res. 88, 536-540.
14. Shainberg, A. and Pearl, R. (1983) Activity of muscle cultures measured by 2-deoxyolucose uptake. Int. J. Dev. Neurosci. 1, 267-271.
15. Sofer, S. and Gueron, M. (1990) Vasodilators and hypertensive encephalopathy following scorpion envenomation in children. Chest 97, 118-120.
16. Sofer, S., Shahak, E. and Gueron, M. (1994) Scorpion envenomation and antivenom therapy. J. Pediatr. 124, 973-978.
17. Sperelakis, N., Shigenobu, K. and McLean, M. J. (1975) In: Developmental and Physiological Correlates of Cardiac Muscle, pp. 209-233 (Lieberman, M. and Sano, T., Eds). New York: Raven Press.
18. 2+-release channel of sarcoplasmic reticulum by a novel scorpion venom. J. biol. Chem. 266, 19135-19138.
19. 2+-release channel of skeletal and cardiac muscle. Proc. natn. Acad. Sci. U.S.A. 89, 12185-12189.
20. Weinstein, L., Brik, H., Rotmansch, H. H. and Shainberg, A. (1991) Characterization of sarcoplasmic reticulum in skinned heart muscle cultures. J. Cell. Physiol. 148, 124-132.
21. Yarom, R. and Braun, K. (1971) Ca changes in myocardium following scorpion venom injection. J. mol. Cell. Cardiol. 2, 177-179.
22. Yarom, R. and Braun, K. (1971) Electron microscopic studies of the myocardial changes produced by scorpion venom injections in dogs. Lab. Invest. 24, 21-30.
23. Yarom, R. and Meiri, U. (1972) Effect of scorpion venom on ultrastructure of frog sartorius muscle. Toxicon 10, 291-294.
24. Yarom, R., Yallon, S., Notowits, F. and Braun, K. (1974) Reversible myocardial damage by scorpion venom in perfused rat heart. Toxicon 12, 347-351.
25. Zlotkin, E., Eitan, M., Bindokas, V. P., Adams, M. E., Moyer, M., Burkhart, W. and Fowler, E. (1991) Functional duality and structural uniqueness of depressant insect-selective neurotoxins. Biochemistry 30, 4814-4821.