Effects of excitotoxic lesions of the rat ventral striatum on the perception of reward cost

Experimental Brain Research

Volumn 123, Issue 4, 1998, Pages 439-448

  Bowman, Eric M ^a   Brown, Verity J ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

Incentive motivation; Mesolimbic dopamine; Nucleus accumbens; Operant conditioning; Reinforcement

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; MALE; MOTIVATION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD;

ANIMALS; BEHAVIOR, ANIMAL; CONDITIONING, OPERANT; CORPUS STRIATUM; LIMBIC SYSTEM; MALE; MOTIVATION; NERVE DEGENERATION; NEUROTOXINS; NUCLEUS ACCUMBENS; RATS; RATS, INBRED STRAINS; REACTION TIME; REWARD;

EID: 0031726492     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002210050588     Document Type: Article

References (37)

1. Annett LE, MacGregor A, Robbins TW (1988) The effects of ibotenic acid lesions of the nucleus accumbens on spatial learning and extinction in the rat. Behav Brain Res 31:231-242
2. Apicella P, Scarnati E, Schultz W (1991) Tonically discharging neurons of monkey striatum respond to preparatory and rewarding stimuli. Exp Brain Res 84:672-675
3. Ballaine B, Killcross S (1994) Effects of ibotenic acid lesions of the nucleus accumbens on instrumental action. Behav Brain Res 65:181-193
4. Bowman EM, Brown VJ (1996) Lesions of the rat ventral striatum change performance in a progressive fixed ratio schedule of reinforcement without affecting reaction times when visual cues indicate reward cost. Soc Neurosci Abstr 22:446
5. Bowman EM, Aigner TG, Richmond BJ (1996) Neuronal signals in the monkey ventral striatum related to motivation for juice and cocaine rewards. J Neurophysiol 75:1061-1073
6. Brown VJ, Bowman HM (1995) Discriminative cues indicating reward magnitude continue to determine reaction time of rats following lesions of the nucleus accumbens. Eur J Neurosci 7:2479-2485
7. Brown RG, Marsden CD (1988) Internal versus external cues and the control of attention in Parkinson's disease. Brain 111:323-345
8. Brown VJ, Brasted PJ, Bowman EM (1996a) The effect of systemic D-amphetamine on motor versus motivational processes in the rat. Psychopharm 128: 171-180
9. Brown VJ, Latimer M, Winn P (1996b) Memory for the changing cost of a reward is mediated by the sublenticular extended amygdala. Brain Res Bull 39:163-170
10. Brown VJ, Davidson C, Bowman EM (1997) Effects of ventral striatal dopamine depletion on the acquisition of progressive ratio responding in the rat. Soc Neurosci Astr 23:1063
11. Carelli RM, Deadwyler SA (1994) A comparison of nucleus-accumbens neuronal firing patterns during cocaine self-administration and water reinforcement in rats. J Neurosci 14:7735-7746
12. Carli M, Jones GH, Robbins TW (1989) Effects of unilateral dorsal and ventral striatal dopamine depletion on visual neglect in the rat: a neural and behavioural analysis. Neuroscience 29: 309-327
13. Chang J, Sawyer SF, Lee R, Woodward DJ (1994) Electrophysiological and pharmacological evidence for the role of the nucleus accumbens in cocaine self-administration in freely moving rats. J Neurosci 14:1224-1244
14. Cousins MS, Salamone JD (1994) Nucleus-accumbens dopamine depletions in rats affect relative response allocation in a novel cost/benefit procedure. Pharmacol Biochem Behav 49:85-91
15. Cousins MS, Atherton A, Turner L, Salamone JD (1996) Nucleus-accumbens dopamine depletions alter relative response allocation in a T-maze cost/benefit task. Behav Brain Res 74:189-197
16. Crossman EK (1971) The effect of fixed-ratio size in multiple and mixed fixed-ratio schedules. Psychol Rec 21:535-544
17. Dunnett SB, Robbins TW (1992) The functional role of mesotelencephalic dopamine systems. Biol Rev 67:491-518
18. Hodos W (1961) Progressive ratio as a measure of reward strength. Science 134:943-944
19. Ljungberg T, Apicella P, Schultz W (1992) Responses of monkey dopamine neurones during learning of behavioral reactions. J Neurophysiol 67:145-163
20. Mishkin M, Appenzeller T (1987) The anatomy of memory. Sci Am 256:80-89
21. Mishkin M, Petri HL (1984) Memories and habits: some implications for the analysis of learning and retention. In: Squire LR, Butters N (eds) Neuropsychology of memory. Guilford Press, New York, pp 287-296
22. Mogenson GJ, Jones DL, Yim CY (1980) From motivation to action: functional interface between the limbic system and the motor system. Prog Neurobiol 14:69-97
23. Neill DB (1982) Commentary on Wise (1982): problems of concept and vocabulary in the anhedonia hypothesis. Behav Brain Sci 5:70
24. Neill DB, Justice JB (1981) An hypothesis for a behavioral function of dopaminergic transmission in nucleus accumbens. In: Chronister RB, DeFrance JF (eds) The neurobiology of the nucleus accumbens. Haer Institute, Brunswick, pp 343-450
25. Reading PJ, Dunnett SB (1991) The effects of excitotoxic lesions of the nucleus accumbens on a matching to position task. Behav Brain Res 46:17-29
26. Reading PJ, Dunnett SB (1995) Embryonic striatal grafts reverse the disinhibitory effects of ibotenic acid lesions of the ventral striatum. Exp Brain Res 105:76-86
27. Robbins TW, Everitt BJ (1996) Neurobiological mechanisms of reward and motivation. Curr Opin Neurobiol 6:228-236
28. Salamone JD, Cousins MS, Butcher S (1994) Anhedonia or anergia - effects of haloperidol and nucleus-accumbens dopamine depletion on instrumental response selection in a T-maze cost-benefit procedure. Behav Brain Res 65:221-229
29. Schultz W, Apicella P, Scarnati E, Ljungberg T (1992) Neuronal activity in monkey ventral striatum related to the expectation of reward. J Neurosci 12:4595-4610
30. Shidara M, Aigner TG, Richmond BJ (1998) Neuronal signals in the monkey ventral striatum related to progress through a predictable series of trials. J Neurosci 18:2613-2625
31. Sinnamon HM (1982) Commentary on Wise (1982): The reward-effort model: an economic framework for examining the mechanism of neuroleptic action. Behav Brain Sci 5:73
32. Stern CE, Passingham RE (1994) The nucleus accumbens in monkeys (Macaca fascicularis). I. The organization of behavior. Behav Brain Res 61:9-21
33. Taghzouti K, Simon H, Le Moal M (1985) Disturbances in exploratory behavior and functional recovery in the Y and radial arm maze following dopaminergic depletion in the lateral septum. Behav Neural Biol 44:354-363
34. Taylor JR, Robbins TW (1984) Enhanced behavioural control by conditioned reinforcers following microinjections of D-amphetamine into the nucleus accumbens. Psychopharmacology 84:405-412
35. Whishaw IQ, Kornelsen RA (1993) Two types of motivation revealed by ibotenic acid nucleus accumbens lesions: dissociation of food carrying and hoarding and the role of primary and incentive motivation. Behav Brain Res 55:283-295
36. Willner P, Scheel-Kruger J (1991) The mesolimbic dopamine system: from motivation to action. Wiley, Chichester
37. Wise RA (1982) Neuroleptics and operant behavior: the anhedonia hypothesis. Behav Brain Sci 5:39-87