The yeast nuclear gene DSS1, which codes for a putative RNase II, is necessary for the function of the mitochondrial degradosome in processing and turnover of RNA

Molecular and General Genetics

Volumn 260, Issue 1, 1998, Pages 108-114

  Dziembowski, A ^a   Malewicz, M ^a   Minczuk, M ^a   Golik, P ^a   Dmochowska, A ^a   Stepien, P P ^a  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

Author keywords

Mitochondria; RNA helicase; RNA turnover; RNase II; Saccharomyces cerevisiae

Indexed keywords

EXORIBONUCLEASE; GENE PRODUCT; MESSENGER RNA; RIBONUCLEASE; RIBOSOME RNA; RNA HELICASE;

ARTICLE; ENZYME ACTIVITY; GENE DELETION; GENOME; INTRON; MITOCHONDRION; PRIORITY JOURNAL; RNA METABOLISM; SACCHAROMYCES CEREVISIAE; SUPPRESSOR GENE;

ANIMALS; CELL NUCLEUS; CRICETINAE; DEAD-BOX RNA HELICASES; ENDORIBONUCLEASES; EXORIBONUCLEASES; FUNGAL PROTEINS; GENES, FUNGAL; MITOCHONDRIA; MULTIENZYME COMPLEXES; POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE; RNA HELICASES; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, FUNGAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0031725399     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050876     Document Type: Article

References (25)

1. Beelman CA, Parker R (1995) Degradation of RNA in eukaryotes. Cell 81:179-183
2. Conrad-Webb H, Perlman PS, Zhu H, Butow RA (1990) The nuclear SUV3-1 mutation affects a variety of post-transcriptional processes in yeast mitochondria. Nucleic Acids Res 18:1369-1376
3. Dmochowska A, Golik P, Stepien PP (1995) The novel nuclear gene DSS1 of Saccharomyces cerevisiae is necessary for mitochondrial biogenesis. Curr Genet 28:108-113
4. Garriga G, Bertrand H, Lambowitz AM (1984) RNA splicing in Neurospora mitochondria: nuclear mutants defective in both splicing and 3′ end synthesis of the large rRNA. Cell 36:623-634
5. Golik P, Szczepanek T, Bartnik E, Stepien PP, Lazowska J (1995) The S. cerevisiae nuclear gene SUV3 encoding a putative RNA helicase is necessary for the stability of mitochondrial transcripts containing multiple introns. Curr Genet 28:217-224
6. Hajnsdorf E, Steier O, Coscoy L, Teysset L, Regnier P (1994) Roles of RNase E, RNase H and PNPase in the degradation of the rpsO transcripts of Escherichia coli: stabilizing function of RNase II and evidence for efficient degradation in an ams pup rub mutant. EMBO J 13:3368-3377
7. Hofmann TJ, Min J, Zassenhaus HP (1993) Formation of the 3′ end of yeast mitochondrial mRNAs occurs by site-specific cleavage two bases downstream of a conserved dodecamer sequence. Yeast 9:1319-1330
8. Iost I, Dreyfus M (1994) mRNAs can be stabilized by DEAD-box proteins. Nature 372:193-196
9. Margossian SP, Butow RA (1996) RNA turnover and the control of mitochondrial gene expression. Trends Biochem Sci 21:392-396
10. Margossian SP, Li H, Zassenhaus HP, Butow RA (1996) The DExH box protein Suv3p is a component of a yeast mitochondrial 3′-to-5′ exoribonuclease that supresses group I intron toxicity. Cell 84:199-209
11. McKee EE, Poyton RO (1984) Optimization of protein synthesis in yeast mitochondria. J Biol Chem 259:9320-9331
12. Min JJ, Zassenhaus HP (1993) Identification of a protein complex that binds to a dodecamer sequence found at the 3′ ends of yeast mitochondrial mRNAs. Mol Cell Biol 13:4167-4173
13. Min JJ, Heuretz RM, Zassenhaus HP (1992) Isolation and characterization of an NTP-dependent 3′-5′ exoribonuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 268:7350-7357
14. Mitchell P, Petfalski E, Shevchenko A, Mann M, Tollervey D (1997) The exosome: a conserved eukaryotic RNA processing complex containing multiple 3′-5′ exoribonucleases. Cell 91:457-466
15. Osinga KA, De Vries E, Van der Horst G, Tabak HF (1984) Processing of yeast mitochondrial messenger RNAs at a conserved dodecamer sequence. EMBO J 3:827-834
16. Py B, Higgins CF, Krish HM, Corpoussis AJ (1996) A DEAD-box helicase in the Escherichia coli degradosome. Nature 381:169-172
17. Rose MD, Winston F, Hieter P (1990) Methods in yeast genetics, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
18. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
19. Sanchirico M, Tzellas A, Fox TD, Conrad-Webb H, Perlman PS, Mason TL (1995) Relocation of the unusual VAR1 gene from the mitochondrion to the nucleus. Biochem Cell Biol 73:987-995
20. Seraphin B, Boulet A, Simon M, Faye G (1987) Construction of a yeast strain devoid of mitochondrial introns and its use to screen nuclear genes involved in mitochondrial splicing. Proc Natl Acad Sci USA 84:6810-6814
21. Stepien PP, Butow RA (1989) Yeast colony Northern: a last method for detection of transcripts by colony hybridization. Nucleic Acids Res 18:380
22. Stepien PP, Margossian SP, Landsman D, Butow RA (1992) The yeast nuclear gene SUV3 affecting mitochondrial post-transcriptional events encodes a putative ATP-dependent RNA helicase. Proc Natl Acad Sci USA 89:6813-6817
23. Stepien PP, Kokot L, Leski T, Bartnik E (1995) The suv3 nuclear gene product is required for the in vivo processing of the yeast mitochondrial 21S rRNA transcripts containing the r1 intron. Curr Genet 27:234-238
24. Vincent RD, Hofman TJ, Zassenhaus HP (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16: 3297 3312
25. Zassenhaus HP, Hofmann TJ, Uthayashanker R, Vincent RD, Zona M (1988) Construction of a yeast mutant lacking the mitochondrial nuclease. Nucleic Acids Res 16:3283-3296