Voltammetric studies on mechanisms of dopamine efflux in the presence of substrates and cocaine from cells expressing human norepinephrine transporter

Journal of Neurochemistry

Volumn 71, Issue 2, 1998, Pages 653-665

  Chen, Nianhang ^a,b   Trowbridge, C G ^b   Justice Jr , J B ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b EMORY UNIVERSITY   (United States)

Author keywords

Cocaine; Dopamine; Human norepinephrine transporter; M Tyramine; Rotating disk electrode voltammetry; Phenethylamine

Indexed keywords

COCAINE; DESIPRAMINE; DOPAMINE TRANSPORTER; NISOXETINE; NORADRENALIN; NORADRENALIN TRANSPORTER; PHENETHYLAMINE; POTASSIUM; TYRAMINE; UNCLASSIFIED DRUG; VALINOMYCIN; VERATRIDINE;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOPAMINE UPTAKE; DOSE TIME EFFECT RELATION; DRUG BRAIN LEVEL; DRUG TRANSPORT; HUMAN; INHIBITION KINETICS; MEMBRANE POTENTIAL; MICHAELIS CONSTANT; NEUROTRANSMITTER RELEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSPORT KINETICS;

ANIMALIA;

EID: 0031724971     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71020653.x     Document Type: Article

References (39)

1. Almers W. and Tse F. W. (1990) Transmitter release from synapses: does a preassembled fusion pore initiate exocytosis? Neuron 4, 813-818.
2. Azzaro A. J., Ziance R. J., and Rutledge C. O. (1974) The importance of neuronal uptake of amines for amphetamine-induced release of 3H-norepinephrine from isolated brain tissue. J. Pharmacol. Exp. Ther. 189, 110-118.
3. Baumann P. A. and Maitre L. (1976) Is drug inhibition of dopamine uptake a misinterpretation of in vitro experiments? Nature 264, 789-790.
4. Bönisch H. (1988) The role of co-transported sodium in the effect of indirectly acting sympathomimetic amines. Naunyn Schmiedebergs Arch. Pharmacol. 332, 135-141.
5. Bönisch H. and Bruss M. (1994) The noradrenaline transporter of the neuronal plasma membrane. Ann. NY Acad. Sci. 733, 193-202.
6. Burnette W. B., Bailey M. D., Kukoyi S., Blakely R. D., Trowbridge C. G., and Justice J. B. Jr. (1996) Human norepinephrine transporter kinetics using rotating disk electrode voltammetry. Anal. Chem. 68, 2932-2938.
7. DeLean A., Munson P. J., and Rodbard D. (1978) Simultaneous analysis of families of sigmoid curves: application to bioassay, radioligand assay, and physiological dose-response curves. Am. J. Physiol. 235, E97-E102.
8. Earles C. and Schenk J. O. (1997) Comparison of dopamine transport and its inhibition in HEK cells expressing human dopamine transporter to that observed in rat nucleus accumbens and striatum by rotating disk electrodes in vitro. Soc. Neurosci. Abstr. 23, 2037.
9. Elverfors A., Jonason J., Jonason G., and Nissbrandt H. (1997) Effects of drugs interfering with sodium channels and calcium channels on the release of endogenous dopamine from super-fused substantia nigra slices. Synapse 26, 359-369.
10. Eshleman A. J., Henningsen R. A., Neve K. A., and Janowsky A. (1994) Release of dopamine via the human transporter. Mol. Pharmacol 45, 312-316.
11. Eshleman A. J., Stewart E., Evenson A. K., Mason J. N., Blakely R. D., Janowsky A., and Neve K. A. (1997) Metabolism of catecholamines by catechol-O-methyltransferase in cells expressing recombinant catecholamine transporters. J. Neurochem. 69, 1459-1466.
12. Fischer J. B. and Cho A. K. (1979) Chemical release of dopamine from striatal homogenates: evidence for an exchange diffusion model. J. Pharmacol. Exp. Ther. 208, 203-209.
13. Giros B., El Mestikawy S., Godinot N., Zheng K., Man H., Yang-Feng T., and Caron M. G. (1992) Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter. Mol. Pharmacol. 42, 383-390.
14. Gu H., Wall S., and Rudnick G. (1994) Stable expression of biogenic amine transporter reveals differences in inhibitors sensitivity, kinetics, and ion dependence. J. Biol. Chem. 269, 7124-7130.
15. Gu H., Wall S., and Rudnick G. (1996) Ion coupling stoichiometry for the norepinephrine transporter in membrane vesicles from stably transfected cells. J. Biol. Chem. 271, 6911-6916.
16. Higuchi H., Matsuo T., and Shimamoto K. (1962) Effect of metham-phetamine and cocaine on the depletion of catecholamine of the brain, heart and adrenal gland in rabbit by reserpine. Jpn. J. Pharmacol. 12, 48-56.
17. Justice J. B. Jr. and Reed B. (1997) Dual electrode characterization of induced efflux of dopamine by m-tyramine via the norepinephrine transporter. Soc. Neurosci. Abstr. 23, 695.
18. + but not dopamine through the rat dopamine transporter. Eur. J. Pharmacol. 309, 107-109.
19. 1 ; multifactorial induction of outward transport. Naunyn Schmiedebergs Arch. Pharmacol. 336, 602-610.
20. Levi G. and Raiteri M. (1993) Carrier-mediated release of neurotransmitters. Trends Neurol. Sci. 16, 415-419.
21. Liang N. Y. and Rutledge C. O. (1982) Evidence for carrier-mediated efflux of dopamine from corpus striatum. Biochem. Pharmacol. 31, 2479-2487.
22. Lowry O. H., Rosebrough N. J., Fair A. L., and Randall R. J. (1951) Protein measurement with the Polin phenol reagent. J. Biol. Chem. 193, 265-275.
23. Mark F. and Bönisch H. (1979) Dissociation constants and lipophilicity of catecholamines and related compounds. Naunyn Schmiedebergs Arch. Pharmacol. 310, 1-9.
24. Meiergerd S. M. and Schenk J. O. (1995) Measurement of the time-resolved kinetics of biogenic amine release and transporter activity by rotating disk electrode voltammetry in vitro, in Neuromethods, Vol. 27: Voltammetric Methods in Brain Systems (Boulton A., Baker G., and Adams R. N., eds), pp. 305-337. Humana Press, Totowa, New Jersey.
25. Pacholczyk T., Blakely R. D., and Amara S. G. (1991) Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter. Nature 350, 350-354.
26. Parker E. M. and Cubeddu L. X. (1986) Comparative effects of amphetamine, phenylethylamine and related drugs on dopamine efflux, dopamine uptake and mazindol binding. J. Pharmacol. Exp. Ther. 245, 199-210.
27. Paton D. M. (1975) Structure-activity relations for the acceleration of efflux of noradrenaline from adrenergic nerves in rabbit atria by sympathomimetic amines. Can. J. Physiol. Pharmacol. 53, 822-829.
28. Pifl C., Drobny H., Reither H., Hornykiewicz O., and Singer E. A. (1995) Mechanism of the dopamine-releasing actions of amphetamine and cocaine: plasmalemmal dopamine transporter versus vesicular monoamine transporter. Mol. Pharmacol. 47, 368-373.
29. - of cocaine sensitive carrier-mediated efflux of amines from cells transfected with the cloned human catecholamine transporters. Br. J. Pharmacol. 121, 205-212.
30. Powis D. A., Madsen G. M., and Torok T. L. (1988) Augmentation of the indirect sympathomimetic action of tyramine by cardioactive steroids is a consequence of elevated intracellular sodium. Naunyn Schmiedebergs Arch. Pharmacol. 337, 273-278.
31. 3H] norepinephrine induced by various agents in hypothalamic synaptosomes. Mol. Pharmacol. 13, 746-758.
32. Raiteri M., Cerrito F., Cervoni A. M., and Levi G. (1979) Dopamine can be released by two mechanisms differentially affected by the dopamine transport inhibitor nomifensine. J. Pharmacol. Exp. Ther. 208, 195-202.
33. Reith M. E. A. and Coffey L. L. (1994) Structure-activity relationship for cocaine congeners in inhibiting dopamine uptake into rat brain synaptic vesicles and bovine chromaffin granule ghosts. J. Pharmacol. Exp. Ther. 271, 1444-1452.
34. Rudnick G. (1997) Mechanisms of biogenic amine neurotransmitter transporters, in Neurotransmitter Transporters: Structure, Function, and Regulation (Reith M. E. A., ed), pp. 73-100. Humana Press, Totowa, New Jersey.
35. Sonders M. S., Zhu S.-J., Zahniser N. R., Kavanaugh M. P., and Amara S. G. (1997) Multiple ionic conductances of the human dopamine transporter: the action of dopamine and psychostimulants. J. Neurosci. 17, 960-974.
36. Stein W. D. (1986) Transport and Diffusion Across Cell Membranes, pp. 107-112. Academic Press, San Diego.
37. Sulzer D. and Rayport S. (1990) Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action. Neuron 5, 797-808.
38. Wall S. G., Gu H., and Rudnick G. (1995) Biogenic amine flux mediated by cloned transporters stably expressed in cultured cell lines: amphetamine specificity for inhibition and efflux. Mol. Pharmacol. 47, 544-550.
39. Wayment H. and Schenk J. O. (1997) Kinetic analyses of outwardly-directed striatal dopaminergic transport in vitro. Soc. Neurosci. Abstr. 23, 2038.