Analysis of mutations at the DNA repair genes in acute childhood leukaemia

British Journal of Haematology

Volumn 103, Issue 2, 1998, Pages 462-466

  Lin, Ying Wei ^a   Kubota, Masaru ^a   Koishi, Seiji ^a   Sawada, Machiko ^a   Usami, Ikuya ^a   Watanabe, Ken Ichiro ^a   Akiyama, Yuichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Acute childhood leukaemia; DNA repair; ERCC1; RT PCR

Indexed keywords

ADOLESCENT; ARTICLE; BLAST CELL; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; DNA REPAIR; EXCISION REPAIR; FEMALE; GENE MAPPING; GENE MUTATION; GENETIC ANALYSIS; GENETIC LINKAGE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MALE; PATHOGENESIS; PRESCHOOL CHILD; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD;

ACUTE DISEASE; ADOLESCENT; BLOTTING, WESTERN; CHILD; CHILD, PRESCHOOL; DNA REPAIR; DNA, NEOPLASM; DNA-BINDING PROTEINS; ENDONUCLEASES; FEMALE; HUMANS; LEUKEMIA; MALE; MUTATION; NEOPLASM PROTEINS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0031724790     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00973.x     Document Type: Article

References (25)

1. Andersson, B.S., Sadeghi, T., Siciliano, M.J., Legerski, R. & Murray, D. (1996) Nucleotide excision repair genes as determinants of cellular sensitivity to cyclophosphamide analogs. Cancer Chemotherapy and Pharmacology, 38, 406-416.
2. Auerbach, A.D. & Allen, R.G. (1991) Leukemia and preleukemia in Fanconi anemia patients: a review of the literature and report of the International Fanconi Anemia Registry. Cancer Genetics and Cytogenetics, 51, 1-12.
3. Baccichet, A., Benachenhou, N., Couture, F., Leclere, J.M. & Sinnett, D. (1997) Microsatellite Instability in childhood T cell acute lymphoblastic leukemia. Leukemia, 11, 797-802.
4. Bicher, A., Ault, K., Kimmelman, A., Gershenson, D., Reed, F., & Liang, B. (1997) Loss of heterozygosity in human ovarian cancer on chromosome 19q. Gynecologic Oncology, 66, 36-40.
5. Cave, H., Guidal, C., Elion, J., Vilmer, E. & Grandchamp, B. (1996) A low rate of loss of heterozygosity is found at many different loci in childhood B-lineage acute lymphocytic leukemia. Leukemia, 10, 1486-1491.
6. Cleaver, J.E. (1994) It was a very good year for DNA repair. Cell, 76, 1-4.
7. Dabholkar, M.D., Berger, M.S., Vionnet, J.A., Egwuagu, C., Silber, J.R., Yu, J.J. & Reed, E. (1995) Malignant and nonmalignant brain tissues differ in their messenger RNA expression patterns for ERCC1 and ERCC2. Cancer Research, 55, 1261-1256.
8. Dabholkar, M., Bostick-Bruton, F., Weber, C., Bohr, VA., Kgwuagu, C. & Reed, E. (1992) ERCC1 and ERCC2 expression in malignant tissues from ovarian cancer patients. Journal of the National Cancer Institute, 84, 1512-1517.
9. de Vries, A., van Oostrom, C.T.M., Hofhuis, F.M., Dortant, P.M., Berg, R.J., de Gruiji, F.R., Wester, P.W., van Krekiji, C., Capel, P.J., van Steeg, H. & Verbeek, S.J. (1995) Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA. Nature, 377, 169-173.
10. Fishel, R., Lescoe, M.K., Rao, M.R.S., Copeland, N.G., Jenkins, N.A., Garber, J., Kane, M. & Kolodner, R. (1993) The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell, 75, 1027-1038.
11. Geleziunas, R., McQuillan, A., Malapetsa, A., Hutchinson, M., Kopriva, D., Wainberg, M.A., Hiscott, J., Bramson, J. & Panasci, L. (1991) Increased DNA synthesis and repair-enzyme expression in lymphocytes from patients with chronic lymphocytic leukemia resistant to nitrogen mustards. Journal of the National Cancer Institute, 83, 557-564.
12. Hangaishi, A., Ogawa, S., Milani, K., Hosoya, N., Chiba, S., Yazuki, Y. & Hirai, H. (1997) Mutations and loss of expression of a mismatch repair gene, hMLH1, in leukemia and lymphoma cell lines. Blood, 89, 1740-1747.
13. Hoeijmakers, J.H.J. (1993) Nucleotide excision repair II: from yeast to mammals. Trends in Genetics, 9, 211-217.
14. Leach, F.S., Nicolaides, N.C., Papadopoulos, N., Liu, B., Jen, J., Parsons, R., Peltomaki, P., Sistonen, P., Aaltonen, L.A., Nystrom-Hahti, M., Guan, X.Y., Zhang, J., Meltzer, P.S., Yu, J.W., Kao, F.T., Chen, D.J., Ccrosarctti, K.M., Founier, R.E.K., Todd, S., Lewis, T., Leach, R.J., Naylor, S.L., Weissenbach, J., Mecklin, J.P., Jarvinen, H., Petersen, G.M., Hamilton, S.R., Green, J., Jass, J., Watson, P., Lynch, H.T., Trent, J.M., de la Chapelle, A., Kinzler, K.W. & Vogelstein, B. (1993) Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell, 75, 1215-1225.
15. Matsunaga, T., Mu. D., Park, C.H., Reardon, J.T. & Sancar, A. (1995) Human DNA repair excision nuclease: analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodies. Journal of Biological Chemistry, 270, 20862-20869.
16. Modrich, P. (1994) Mismatch repair, genetic instability, and cancer. Science, 266, 1959-1960.
17. Nakane, H., Takeuchi, S., Yuba, S., Saijo, M., Nakatsu, Y., Murai, H., Nakatsuru, Y., Ishikawa, T., Hirota, S., Kitamura, Y., Kato, Y., Tsunoda, Y., Miyauchi, H., Horio, T., Tokunaga, T., Matsunaga, T., Nikaido, O., Nishimune, Y., Okada, Y. & Tanaka, K. (1995) High incidence of ultraviolet-B- or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene, Nature, 377, 165-168.
18. Reitmair, A.H., Schmits, R., Ewel, A., Bapat, B., Redston, M. Mitri, A., Waterhouse, P., Mittrucker, H.W., Wakeham, A., Liu, B., Thomason, A., Griesser, H., Gallinger, S., Ballhausen, W.G., Fishel, R. & Mak, T.W. (1995) MSH-2 deficient mice are viable and susceptible to lymphoid tumours. Nature Genetics, 11, 64-70.
19. Sill, H., Goldman, J.M. & Cross, N.C.P. (1996) Rarity of microsatellite alterations in acute myeloid leukaemia. British Journal of Cancer. 74, 255-257.
20. Simpson, P.J. (1987) An improved method for mRNA isolation and characterization of in vitro translation products by Western blotting. Gene, 56, 161-171.
21. Taylor, A.M.R., Metcalfe, J.A., Thick, J. & Mak, Y.F. (1995) Leukemia and lymphoma in ataxia telangiectasia. Blood, 87, 423-438.
22. van Duin, M., de Wil, J., Odijk, H., Westerveld, A., Yasui, A., Koken, M.H.M., Hoeijmakers, J.H.J. & Bootsma. D. (1986) Molecular characterization of the human excision repair gene ERCC1 : cDNA cloning and amino acid homology with the yeast DNA repair gene RADIO. Cell, 44, 913-923.
23. Verma, I.M. (1975) Studies on reverse transcriptase of RNA tumor viruses. III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H. Journal of Virology, 15, 843-854.
24. Wei, Q., Xu, X., Cheng, L., Legerski, R.J. & Ali, O.F. (1995) Simultaneous amplification of four DNA repair genes and beta-actin in human lymphocytes by multiplex reverse transcriptase-PCR. Cancer Research, 55, 5025-5029.
25. Wu, C., Nagasaki, H., Maruyama, K., Nakabeppu, Y., Sekiguchi, M. & Yuasa, Y. (1995) Polymorphisms and probable lack of mutation in a human mutT homolog, hMTH1. in hereditary nonpoliposis colorectal cancer. Biochemical and Biophysical Research Communications, 214, 1239-1245.