Critical role of conserved histidine pairs HNXXH and HDXXH in recombinant human phosphodiesterase 4A

Cellular Signalling

Volumn 10, Issue 7, 1998, Pages 491-497

  Omburo, George A ^a   Jacobitz, Susanne ^b   Torphy, Theodore J ^b   Colman, Robert W ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Histidine motifs; Metal cation; Phosphodiesterase 4A

Indexed keywords

COBALT; HISTIDINE; MAGNESIUM ION; MANGANESE; PHOSPHODIESTERASE IV; RECOMBINANT ENZYME; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; AMINO ACID SEQUENCE; CONSERVED SEQUENCE; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; MUTAGENESIS; RECOMBINANT FUSION PROTEINS;

EID: 0031719432     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0898-6568(97)00175-7     Document Type: Article

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