Trophoblast IFN-τ differentially induces lymphopenia and neutropenia in lambs

Journal of Interferon and Cytokine Research

Volumn 18, Issue 9, 1998, Pages 731-737

  Tuo, Wenbin ^a,b   Brown, Wendy C ^b,c   Roger, Elizabeth ^a   Zhu, Daming ^a,b   Lin, Guanbin ^a   Smith III, Roger ^c   Bazer, Fuller W ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b WASHINGTON STATE UNIVERSITY   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG EFFECT; DRUG INDUCED DISEASE; FLOW CYTOMETRY; LAMB; LYMPHOCYTE PROLIFERATION; LYMPHOCYTOPENIA; NEUTROPENIA; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; TROPHOBLAST;

ANIMALIA; OVIS; OVIS ARIES;

EID: 0031719401     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1998.18.731     Document Type: Article

References (56)

1. BAZER, F.W., SPENCER, T.E., and OTT, T.L. (1997). Interferon tau: a novel pregnancy recognition signal. Am. J. Reprod. Immunol. 37, 412-420.
2. PONTZER, C.H., TORRES, B.A., VALLET, J.L., BAZER, F.W., and JOHNSON, H.M. (1988). Antiviral activity of the pregnancy recognition hormone ovine trophoblast protein-1. Biochem. Biophys. Res. Commun. 152, 801-807.
3. PONTZER, C.H., OTT, T.L., BAZER, F.W., and JOHNSON, H.M. (1990). Localization of an antiviral site on the pregnancy recognition hormone, ovine trophoblast protein 1. Proc. Natl. Acad. Sci. USA. 87, 5945-5949.
4. TUO, W., OTT, T.L., and BAZER, F.W. (1993). Natural killer cell activity of lymphocytes exposed to ovine, type 1, trophoblast interferon. Am. J. Reprod. Immunol. 29, 26-34.
5. PONTZER, C.H., BAZER, F.W., and JOHNSON, H.M. (1991). Antiproliferative activity of a pregnancy recognition hormone, ovine trophoblast protein-1. Cancer Res. 51, 5304-5307.
6. MARTAL, J., DE LA LLOSA-HERMIER, M.P., CHENE, N., HUYNH, L., MILLET, S., L'HARIDON, R., ASSAL, A., ROIGNANT, N., and CHAOUAT, G. (1995). Trophoblastic interferons and embryonal immune tolerance. Contracept Fertil. Sex 23, 562-572.
7. BAZER, F.W., and JOHNSON, H.M. (1991). Type I conceptus interferons: maternal recognition of pregnancy signals and potential therapeutic agents. Am. J. Reprod. Immunol. 26, 19-22.
8. NEWTON, G.R., VALLET, J.L., HANSEN, P.J., and BAZER, F.W. (1989). Inhibition of lymphocyte proliferation by ovine trophoblast protein-1 and a high molecular weight glycoprotein produced by the peri-implantation sheep conceptus. Am. J. Reprod. Immunol. 19, 99-107.
9. ASSAL-MELIANI, A., KINSKY, R., MARTAL, J., and CHAOUAT, G. (1995). In vivo immunosuppressive effects of recombinant ovine interferon-tau (trophoblastin): r.oTP (r.oIFN-tau) inhibits local GVH reaction in mice (PLN assay), prevents fetal resorptions, and favors embryo survival and implantation in the CBA/J x DBA/2 mice combination. Am. J. Reprod. Immunol. 33, 267-275.
10. SPENCER, T.E., BECKER, W.C., GEORGE, P., MIRANDO, M.A., OGLE, T.F., and BAZER, F.W. (1995). Ovine interferon-tau inhibits estrogen receptor up-regulation and estrogen-induced luteolysis in cyclic ewes. Endocrinology 136, 4932-4944.
11. SPENCER, T.E., BECKER, W.C., GEORGE, P., MIRANDO, M.A., OGLE, T.F., and BAZER, F.W. (1995). Ovine interferon-tau regulates expression of endometrial receptors for estrogen and oxytocin but not progesterone. Biol. Reprod. 53, 732-745.
12. CHAOUAT, G., ASSAL-MELIANI, A., MARTAL, J., RAGHUPATHY, R., ELLIOT, J., MOSMANN, T., and WEGMANN, T.G. (1995). IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau. J. Immunol. 154, 4261-4268.
13. LI, J., and ROBERTS, R.M. (1994). Interferon-tau and interferon-alpha interact with the same receptors in bovine endometrium. Use of a readily iodinatable form of recombinant interferon-tau for binding studies. J. Biol. Chem. 269, 13544-13550.
14. SUBRAMANIAM, P.S., KHAN, S.A., PONTZER, C.H., and JOHNSON, H.M. (1995). Differential recognition of the type I interferon receptor by interferons tau and alpha is responsible for their disparate cytotoxicities. Proc. Natl. Acad. Sci. USA 92, 12270-12274.
15. SOOS, J.M., SUBRAMANIAM, P.S., HOBEIKA, A.C., SCHIFFENBAUER, J., and JOHNSON, H.M. (1995). The IFN pregnancy recognition hormone IFN-tau blocks both development and super-antigen reactivation of experimental allergic encephalomyelitis without associated toxicity. J. Immunol. 155, 2747-2753.
16. SOOS, J.M., MUJTABA, M.G., SUBRAMANIAM, P.S., STREIT, W.J., and JOHNSON, H.M. (1997). Oral feeding of interferon tau can prevent the acute and chronic relapsing forms of experimental allergic encephalomyelitis. J. Neuroimmunol. 75, 43-50.
17. SOOS, J.M., SCHIFFENBAUER, J., JOHNSON, H.M., and PONTZER, C.H. (1997). Interferon-tau: a potential treatment for inflammatory central nervous system disease. In: Interferon Therapy of Multiple Sclerosis. A. T. Reder (ed.) New York: Marcel Dekker, pp. 479-498.
18. MUJTABA, M.G., SOOS, J.M., and JOHNSON, H.M. (1997). CD4 T suppressor cells mediate Interferon tau protection against experimental allergic encephalomyelitis. J. Neuroimmunol. 75, 35-42.
19. JANIK, J.E., and STEIS, R.G. (1993). Interferon therapy for malignant and nonmalignant disease. In: Clinical Applications of Cytokines: Role in Pathogenesis. Diagnosis and Therapy. J.J. Oppenheim, J.L. Rossio, and A.J.H. Gearing (eds.) New York: Oxford University Press, pp. 135-145.
20. PONTZER, C.H., YAMAMOTO, J.K., BAZER, F.W., OTT, T.L., and JOHNSON, H.M. (1997). Potent anti-feline immunodeficiency virus and anti-human immunodeficiency virus effect of IFN-tau. J. Immunol. 158, 4351-4357.
21. DEREUDDRE-BOSQUET, N., CLAYETTE, P., MARTIN, M., MABONDZO, A., FR'ETIER, P., GRAS, G., MARTAL, J., and DORMONT, D. (1996). Anti-HIV potential of a new interferon, interferon-tau (trophoblastin). J. Acquir. Immune. Defic. Syndr. Hum. Retrovirol. 11, 241-246.
22. WOODRUFF, J.F., and WOODRUFF, J.J. (1970). Virus-induced alterations of lymphoid tissues. I. Modification of the recirculating pool of small lymphocytes by Newcastle disease virus. Cell. Immunol. 1, 333-354.
23. WOODRUFF, J.F., and WOODRUFF, J.J. (1972). Virus-induced alterations of lymphoid tissues. II. Lymphocyte receptors for Newcastle disease virus. Cell. Immunol. 5, 296-306.
24. WOODRUFF, J.F., and WOODRUFF, J.J. (1972). Virus-induced alterations of lymphoid tissues. III. Fate of radiolabeled thoracic duct lymphocytes in rats inoculated with Newcastle disease virus. Cell. Immunol. 5, 307-317.
25. WOODRUFF, J.F., and WOODRUFF, J.J. (1972). Virus-induced alterations of lymphoid tissues. IV. The effect of Newcastle disease virus on the fate of transfused thoracic duct lymphocytes. Cell. Immunol. 10, 78-85.
26. SCHATTNER, A., MESHORER, A., REVEL, M., and WALLACH, D. (1982). Interferon as a possible cause for virus-related lymphocytopenia. Isr. J. Med. Sci. 18, 965-966.
27. SCHATTNER, A., MESHORER, A., and WALLACH, D. (1983). Involvement of interferon in virus-induced lymphopenia. Cell. Immunol. 79, 11-25.
28. CAHILL, R.N.P., FROST, H., and TRNKA, Z. (1976). The effects of antigen on the migration of recirculating lymphocytes through single lymph nodes. J. Exp. Med. 143, 870-888.
29. GRESSER, I., GUY-GRANTAL, D., MAURY, C., and MAUNOURY, M.-T. (1981). Interferon induces peripheral lymphadenopathy in mice. J. Immunol. 127, 1569-1575.
30. KIMBER, I., SPARSHOTT, S.M., BELL, E.B., and FORD, W.L. (1987). The effects of interferon on the recirculation of lymphocytes in the rat. Immunology 60, 585-591.
31. HEIN, W.R., and SUPERSAXO, A. (1988). Effect of interferon-alpha-2a on the output of recirculating lymphocytes from single lymph nodes. Immunology 64, 469-474.
32. KORNGOLD, R., BLANK, K.J., and MURASKO, D.M. (1983). Effect of interferon on thoracic duct lymphocyte output: induction with either poly I:poly C or vaccinia virus. J. Immunol. 130, 2236-2240.
33. CHUNG, H.-T., SAMLOWSKI, W.E., KELSEY, D.K., and DAYNES, R.D. (1986). Alteration in lymphocyte recirculation within ultraviolet light-irradiated mice: efferent blockade of lymphocyte egress from peripheral lymph nodes. Cell. Immunol. 102, 335-345.
34. 2 as a mediator of cell shutdown. Immunology 42, 225-231.
35. HALL, J.G. (1986). Sulphated polysaccharides, corticosteroids and lymphocyte recirculation. Immunology 57, 275-279.
36. McCONNELL, I., and HOPKINS, J. (1981). Lymphocyte traffic through antigen-stimulated lymph nodes I. Complement activation within lymph nodes initiates cell shutdown. Immunology 42, 217-223.
37. OTT, T.L., VAN-HEEKE, G., JOHNSON, H.M., and BAZER, F.W. (1991). Cloning and expression in Saccharoinyces cerevisiae of a synthetic gene for the type-1 trophoblast i nterferon ovine trophoblast protein-1: purification and antiviral activity. J. Interferon Res. 11, 57-64.
38. MADDOX, J.F., MACKAY, C.R., and BRANDON, M.R. (1985). Surface antigen SBU-T4 and SBU-T8 of sheep lymphocyte subsets defined by monoclonal antibodies. Immunology 55, 739-748.
39. EZAKI, T., MIYASAKA, M., BEYA, M.-F., DUDLER, L., and TRNKA, Z. (1987). A murine anti-sheep T8 monoclonal antibody, ST-8, that defines the cytotoxic T lymphocyte population. Int. Arch. Allergy Appl. Immunol. 82, 168-177.
40. DAVIS, W.C., BROWN, W.C., HAMILTON, M.J., WYATT, C.R., ORDEN, J.A., KHALID, A.M., and NAESSENS, J. (1996). Analysis of monoclonal antibodies specific for the gamma delta TCR. Vet. Immunol. Immunopathol. 52, 275-83.
41. MACKAY, C.R., MADDOX, J.F., and BRANDON, M.R. (1987). A monoclonal antibody to the p220 component of sheep CD45 identifies B cells and unique lymphocyte subsets. Cell. Immunol. 110, 46-55.
42. BEYA, M.-F., MIYASAKA, M., DUDLER, L., EZAK, T., and TRNKA, Z. (1986). Studies on the differentiation of T lympho-cytes in sheep. II. Two monoclonal antibodies that recognize all ovine T lymphocytes. Immunology 57, 115-121.
43. CARR, I. (1977). Lymphoreticular Disease. Oxford, England: Blackwell Scientific Publisher, pp. 21-54.
44. DALE, D.C. (1990). Neutropenia. In: Hematology. 4th ed. W.J. Williams, E. Beutler, A.J. Erslev, and M.A. Lichtman (eds.) New York: McGraw-Hill, pp. 807-816.
45. ERNSTOFF, M.S., and KIRKWOOD, J.M. (1984). Changes in the bone marrow of cancer patients treated with recombinant interferon alpha-2. Am. J. Med. 76, 593-596.
46. DEGR'E, M. (1974). Influence of exogenous interferon on the peripheral white blood cell counl in mice. Int. J. Cancer 14, 699-703.
47. DEGR'E, M. (1973). Influence of polyinosinic:polycytidylic acid on the circulating white blood cells in mice. Proc. Soc. Exp. Biol. Med. 142, 1087-1091.
48. ROBERTS, K., and SHEVACH, E.M. (1991). Immunregulatory role of γδ T cells. Ann. NY Acad. Sci. 636, 1-8.
49. HEIN, W.R., and MACKAY, C.R. (1991). Prominence of gamma delta T cells in the ruminant immune system. Immunol. Today 12, 30-34.
50. YANG, H.Y., DUNDON, P.L., NAHILL, S.R., and WELSH, R.M. (1989). Virus-induced polyclonal cytotoxic T lymphocyte stimulation. J. Immunol. 142, 1710-1718.
51. SELIN, L.K., NAHILL, S.R., and WELSH, R.M. (1994). Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses. J. Exp. Med. 179, 1933-1943.
52. RAZVI, E.S., and WELSH, R.M. (1995). Apoptosis in viral infections. Adv. Virus Res. 45, 1-60.
53. TOUGH, D.E., BORROW, P., and SPRENT, J. (1996). Induction of bystander T cell proliferatoion by viruses and type I interferon in vivo. Science 272, 1947-1950.
54. MACKAY, C.R., MARSTON, W.L., and DUDLER, L. (1990). Naïve and memory T cells show distinct pathways of lymphocyte recirculation. J. Exp. Med. 171, 801-817.
55. ABITORABI, M.A., MACKAY, C.R., JEROME, E.H., OSORIO, O., BUTCHER, E.C., and ERLE, D.J. (1996). Differential expression of homing molecules on recirculating lymphocytes from sheep gut, peripheral, and lung lymph. J. Immunol. 156, 3111-3117.
56. ABERNETHY, N.J., HAY, J.B., KIMPTON, W.O., WASHINGTON, E., and CAHILL, R.N.P. (1991). Lymphocyte subset-specific and tissue-specific lymphocyte-endothelial cell recognition mechanisms independently direct the recirculation of lymphocytes from blood to lymph in sheep. Immunology 72, 239-245.