Nitric oxide synthase inhibition and the induction of cytochrome P-450 affect heme oxygenase-1 messenger RNA expression after partial hepatectomy and acute inflammation in rats

Critical Care Medicine

Volumn 26, Issue 10, 1998, Pages 1683-1689

  Nordmann, Yves ^a  

^a HÔPITAL LOUIS MOURIER   (France)

Author keywords

3',5' cyclic guanosine monophosphate; Acute inflammation; Cytochrome P 450; Heme oxygenase 1; Hepatic regeneration; Nitric oxide synthase

Indexed keywords

CORTICOSTERONE; CYCLIC GMP; CYTOCHROME P450; HEME OXYGENASE; INTERLEUKIN 6; MESSENGER RNA; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CORTICOSTERONE BLOOD LEVEL; CYTOKINE PRODUCTION; ENZYME INDUCTION; ENZYME INHIBITION; INFLAMMATION; LIVER REGENERATION; MALE; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACUTE DISEASE; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE MODELS, ANIMAL; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HEPATECTOMY; INFLAMMATION; LIPOPOLYSACCHARIDES; LIVER REGENERATION; MALE; NITRIC OXIDE SYNTHASE; RANDOM ALLOCATION; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TURPENTINE;

EID: 0031718355     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199810000-00023     Document Type: Article

References (5)

1. Abraham NG, Durmond GS, Lutton JD, et al: The biological significance and physiological role of heme oxygenase. Cellular Physiology Biochemistry 1996; 6:129-168
2. Maines MD, Trakshel GM, Kutty RK: Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible. J Biol Chem 1986; 261:411-419
3. Cruse I, Maines MD: Evidence suggesting that the two forms of heme oxygenase are products of different genes. J Biol Chem 1988; 263:411-419
4. Applegate LA, Luscher P, Tyrrell R: Induction of heme oxygenase: A general response to oxidant stress in cultured mammalian cells. Cancer Res 1991; 51:974-978
5. Geisterfer M, Richard C, Baumann M, et al: Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo. Cytokine 1993; 5:1-7