Effect of media on the dissolution profiles of propranolol hydrochloride from matrices containing different substitution types of Methocel

Pharmacy and Pharmacology Communications

Volumn 4, Issue 8, 1998, Pages 377-383

  Velasco, M Victoria ^a,b   Ford, James L ^a   Rajabi Siahboomi, Ali R ^a  

^a LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCHLORIC ACID; METHYLCELLULOSE; PHOSPHATE; PROPRANOLOL; WATER;

ARTICLE; CONTROLLED STUDY; DRUG RELEASE; DRUG SOLUBILITY;

EID: 0031715352     PISSN: 14608081     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Alderman, D. A. (1984) A review of cellulose ethers in hydrophilic matrices for oral controlled-release dosage forms. Int. J. Pharm. Tech. Prod. Mfr. 5: 1-9
2. Bonferoni, M. C., Rossi, S., Ferrari, F., Bertoni, M., Sinistri, R., Caramella, C. (1995) Characterization of three hydroxy-propylmethylcellulose substitution types: rheological properties and dissolution behaviour. Eur. J. Pharm. Biopharm. 41: 242-246
3. Bonferoni, M. C., Rossi, S., Ferrari, F., Bertoni, M., Caramella, C. (1996) A study of three hydroxypropylmethyl cellulose substitution types: effect of particle size and shape on hydrophilic matrix performances. STP Pharma Sci. 6: 277-284
4. Fagan, P. G., Harrison, P. J., Shankland, N. (1989) A correlation between cloud point and disintegration of hydroxyalkylcellulose controlled release matrices. J. Pharm. Pharmacol. 41: 25P
5. Ford, J. L., Rubinstein, M. H., Changela, A., Hogan, J. A. (1985) Influence of pH on the dissolution of promethazine hydrochloride from hydroxypropylmethylcellulose controlled release tablets. J. Pharm. Pharmacol. 37: 115P
6. Ford, J. L., Rubinstein, M. H., McCaul, F., Hogan, J. E., Edgar, P.E. (1987) Importance of drug type, tablet shape and added diluents on drug release kinetics from hydroxypropylmethylcellulose matrix tablets. Int. J. Pharm. 40: 223-224
7. Ford, J. L., Mitchell, K., Rowe, P., Armstrong, D. J., Elliott, P. N. C., Rostron, C., Hogan, J. E. (1991) Mathematical modelling of drug release from hydroxypropylmethylcellulose matrices: effect of temperature. Int. J. Pharm. 71: 95-140
8. Haque, A., Richarson, R. K., Morris, E. R, Gidley, M. J., Caswell, D. C. (1993) Thermogelation of methylcellulose. Part II: effect of hydroxypropyl substituents. Carbohydr. Polym. 22: 175-186
9. Mitchell, K., Ford, J. L., Armstrong, D. J., Elliot, P. N. C., Rostron, C., Hogan, J. E. (1990) The influence of additives on the cloud point, disintegration and dissolution of hydroxypropylmethylcellulose gels and matrix tablets. Int. J. Pharm. 66: 233-242
10. Mitchell, K., Ford, J. L., Armstrong, D. J., Elliot, P. N. C., Hogan, J. E., Rostron, C. (1993) The influence of substitution type on the performance of methylcellulose and hydroxypropylmethylcellulose in gels and matrices. Int. J. Pharm. 100: 143-154
11. Rajabi-Siahboomi, A. R., Henderson, A., Davies, M. C., Melia C. D. (1993) HPMC hydrophilic matrix systems: structure-activity relationships and release behaviour of diclofenac sodium. J. Pharm. Pharmacol. 45: 1109
12. Rajabi-Siahboomi, A. R., Adler, J., Davies, M. C., Melia C. D. (1994) Particle swelling and the mechanism of failure of HPMC matrices. Proc. 3rd Assoc. UKaps Conf. 21
13. Rajabi-Siahboomi, A. R., Bowtell, R. W., Mansfield, P., Davies, M. C., Melia, C. D. (1996) Structure and behavior in hydrophilic matrix sustained release dosage forms: 4. Studies of water mobility and diffusion coefficients in the gel layer of HPMC tablets using NMR imaging. Pharm. Research. 13: 376-380
14. Sarkar, N. (1979) Thermal gelation properties of methyl and hydroxypropyl methycellulose. J. Appl. Polym. Sci. 24: 1073-1087
15. Sarkar, N. (1995) Kinetics of thermal gelation of methylcellulose and hydroxypropylmethylcellulose in aqueous solutions. Carbohydr. Polym. 26: 195-203
16. Sarkar, N., Walker, L. C. (1995) Hydration-dehydration properties of methylcellulose and hydroxypropylmethylcellulose. Carbohydr. Polym. 27: 177-185