Quantitative and qualitative alterations of long-term culture- initiating cells in patients with acute leukaemia in complete remission

British Journal of Haematology

Volumn 103, Issue 1, 1998, Pages 124-128

  Yao, M ^a   Bouchet, S ^a   Harnois, C ^a   Giarratana, M C ^a,b   Laporte, J P ^a   Gorin, N C ^a   Lopez, M ^a,c   Douay, L ^b,d  

^a BICHAT HOSPITAL   (France)

^b HÔPITAL SAINT ANTOINE   (France)

^c INSERM   (France)

^d ARMAND TROUSSEAU HOSPITAL   (France)

Author keywords

Acute leukaemia; Autografting; Long term culture initiating cells; Mafosfamide; Purging

Indexed keywords

MAFOSFAMIDE;

ACUTE LEUKEMIA; ARTICLE; BONE MARROW CELL; BONE MARROW PURGING; CANCER REGRESSION; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HEMATOPOIESIS; HUMAN; MONONUCLEAR CELL; PRIORITY JOURNAL;

ACUTE DISEASE; ANTINEOPLASTIC AGENTS; BONE MARROW PURGING; CYCLOPHOSPHAMIDE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA, LYMPHOCYTIC; LEUKEMIA, MYELOID; TRANSPLANTATION, AUTOLOGOUS;

EID: 0031714916     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00967.x     Document Type: Article

References (22)

1. Betticher, D.C., Huxol, H., Muller, R., Speck, B. & Nissen, C. (1993) Colony growth in cultures from bone marrow and peripheral blood after curative treatment for leukemia and severe aplasic anemia. Experimental Hematology, 21, 1517-1521.
2. Bonnet, D. & Dick, J.E. (1997) Human acute myeloid leukaemia is organized as a hierarchy that originates from a primitive haematopoietic cell. Nature Medicine, 3, 730-737.
3. Burnett, A.K., Graham, S. & Alcorn, M. (1995) Sustained growth in long term bone marrow culture of AML remission marrow predicts a high probability of remaining relapse free after auto BMT in first complete remission. Experimental Hematology, 21, 1020 (abstract 42).
4. Burnett, A.K., Tansey, P., Watkins, R., Alcorn, M., Maharaya, D., Singer, C.R.J., McKinnon, S., McDonald, G.A. & Robertson, A.G. (1984) Transplantation of unpurified autologous bone marrow in acute myeloid leukaemia in first remission. Lancet, ii, 1068-1074.
5. Chang, J., Geary, C.G. & Testa, N.G. (1990) Long-term bone marrow damage after chemotherapy for acute myeloid leukaemia does not improve with time. British Journal of Haematology, 75, 68-72.
6. Douay, L., Hu, C., Giarratana, M.C., Bouchet, S. & Gorin, N.C. (1995) Amifostine improves the antileukemic therapeutic index of mafosfamide: implications for bone marrow purging. Blood, 86, 2849-2855.
7. Douay, L., Laporte, J.P., Mary, J.Y., Lopez, M., Lemonnier, M.P., Stachowiak, J., Benitez, O., Deloux, J., Najman, A., Salmon, C. & Gorin, N.S. (1987) Differences in kinetics of hematopoietic reconstitution between ALL and ANLL after autologous bone marrow transplantation with marrow treated in vitro with mafosfamide (Asta Z 7577). Bone Marrow Transplantation, 2, 33-43.
8. Douay, L., Mary, J.Y., Giarratana, M.C., Najman, A. & Gorin, N.C. (1989) Establishment of a reliable experimental procedure for bone marrow purging with mafosfamide (Asia Z 7557). Experimental Hematology, 17, 429-432.
9. Gorin, N.C., Douay, L., Laporte, J.P., Lopez, M., Mary, J.Y., Najman, A., Salmon, C., Aegerter, P., Stakowiak, J., David, R., Pene, F., Kantor, G., Deloux, J., Duhamel, E., van den Akker, J., Gerota, J., Parlier, Y. & Duhamel, G. (1986) Autologous bone marrow transplantation using marrow incubated with Asta Z 7557 in adult acute leukemia. Blood, 67, 1367-1376.
10. Greenberger, J.S. (1991) Toxic effects on the hematopoietic microenvironment. Experimental Hematology, 19, 1101-1109.
11. Kobari, L., Giarratana, M.C., Poloni, A., Firat, H., Labopin, M., Gorin, N.C. & Douay, L. (1998) Flt3 ligand, MGDF, Epo and G-CSF enhance ex vivo expansion of hematopoietic cell compartments in the presence of SCF, IL3 and IL6. Bone Marrow Transplantation, 21, 759-767.
12. Laporte, J.P., Douay, L., Lopez, M., Labopin, M., Jouet, J.P., Lesage, S., Stachowiak, J., Fouillard, L., Isnard, F., Noel-Walter, M.P., Pene, F., Deloux, J., van den Akker, J., Grande, M., Bauters, F., Najman, A. & Gorin, N.C. (1994) One hundred twenty-five adult patients with primary acute leukemia autografted with marrow purged by mafosfamide: a 10-year single institution experience. Blood, 84, 5810-5818.
13. Laporte, J.P., Gorin, N.C., Lemonnier, M.P., Isnard, F. & Najman, A. (1988) A new combination of two intercalating agents (Mitoxantrone and Daunomycine) in adult refractory acute leukemia: the DON protocol. Cancer Chemotherapy and Pharmacology, 22, 344-347.
14. Löwenberg, B., Abels, J., Van Bekkum, D.W., Dzoljic, G., Hagenbeek, A., Hendrikds, W.D.H., Van de Poel, J., Skoo, W., Sintnicolaas, K. & Wagemaker, G. (1984) Transplantation of non purified autologous bone marrow in patients with AML in first remission. Cancer, 54, 2840-2849.
15. Neben, S., Hemman, S., Montgomery, M., Farrara, J. & Mauch, P. (1993) Hematopoietic stem cell deficit of transplanted bone marrow previously exposed to cytotoxic agents. Experimental Hematology, 21, 156-162.
16. Sharkis, S.J., Santos, G.W. & Colvin, M. (1980) Elimination of acute myelogenous leukemic cells from marrow and tumor suspensions in the rat with 4-hydroperoxycyclophosphamide. Blood, 55, 521-523.
17. Sirard, C., Lapidot, T., Vormoor, J., Cashman, J.D., Doedens, M., Murdoch, B., Jamal, N., Messner, H., Addey, L., Minden, M., Laraya, P., Keating, A., Eaves, A., Lansdorp, P.M., Eaves, C.J. & Dick, J.E. (1996) Normal and leukemic SCID-repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis. Blood, 87, 1539-1548.
18. Straetmans, N., Ma, D.D.F., Herman, P.H., Zenebergh, A., Chang, A., Deneys, V., De Bruyère, M. & Ferrant, A. (1995) Long-term culture of autologous transplanted bone marrow for acute myeloid leukaemia: evidence for an in vitro haematopoietic defect and lack of correlation with the speed of engraftment. Bone Marrow Transplantation, 15, 421-428.
19. Sutherland, H.J., Blair, A. & Zapf, R.W. (1996) Characterization of a hierarchy in human acute myeloid leukemia progenitor cells. Blood, 87, 4754-4761.
20. Sutherland, H.J., Eaves, C.J., Lansdorp, P.M., Phillips, G.L. & Hogge, D.E. (1994) Kinetics of committed and primitive blood progenitor mobilization after chemotherapy and growth factor treatment and their use in autotransplants. Blood, 83, 3808-3814.
21. Yeager, A.M., Kaizer, H., Santos, G.W., Saral, R., Colvin, O.M., Stuart, R.K., Braine, H.G., Burke, P.J., Ambinder, R.F., Burns, W.H., Fuller, D.J., Davis, J.M., Karp, J.E., May, W.S., Rowley, S.D., Sensenbrenner, L.L., Vogelsang, G.B. & Wingard, J.R. (1986) Autologous bone marrow transplantation in patients with acute nonlymphocytic leukemia, using ex vivo marrow treatment with 4-hydroperoxycyclophosphamide. New England Journal of Medicine, 315, 141-147.
22. Zittoun, R.A., Mandelli, F., Willemze, R., De Witte, T., Labar, B., Resegotti, L., Leoni, F., Damasio, E., Visani, G., Papa, G., Caronia, F., Hayat, M., Stryckmans, P., Rotoli, B., Leoni, P., Peetermans, M.E., Dardenne, M., Vegna, M., Petti, M.C., Solbu, G. & Suciu, S. (1995) Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. New England Journal of Medicine, 332, 217-223.