Hypercholesterolemia enhances oxidant production in mesenteric venules exposed to ischemia/reperfusion

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 18, Issue 10, 1998, Pages 1583-1588

  Kurose, Iwao ^a   Wolf, Robert E ^a   Grisham, Matthew B ^a   Neil Granger, D ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

Mast cell degranulation leukocyte endothelial cell adhesion; Platelet aggregation; Vascular permeability

Indexed keywords

OXIPURINOL; SUPEROXIDE DISMUTASE; XANTHINE OXIDASE;

ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; HYPERCHOLESTEROLEMIA; ISCHEMIA; LEUKOCYTE ADHERENCE; MALE; MAST CELL DEGRANULATION; MESENTERIC ARTERY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; THROMBOCYTE AGGREGATION;

EID: 0031714628     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.18.10.1583     Document Type: Article

References (22)

1. Osborne JA, Mentley RK, Lefer AM. Increased severity of acute myocardial ischemia in experimental atherosclerosis. Heart Vessels. 1987;3:73-79.
2. Golino P, Maroko PR, Carew TE. The effect of acute hypercholesterolemia on myocardial infarct size and the no-reflow phenomenon during coronary occlusion-reperfusion. Circulation. 1987;75:292-298.
3. Gauthier TW, Scalia R, Murohara T, Guo J, Lefer AM. Nitric oxide protects against leukocyte-endothelium interactions in the early stages of hypercholesterolemia. Arterioscler Thromb. 1995;15:1652-1659.
4. Henninger DD, Gerritsen ME, Granger DN. Low-density lipoprotein receptor knock-out mice exhibit exaggerated microvascular responses to inflammatory stimuli. Circ Res. 1997;81:274-281.
5. Kimura M, Kurose I, Russell J, Granger DN. Effects of fluvastatin on leukocyte-endothelial cell adhesion on hypercholesterolcmic rats. Arterioscler Thromb Vasc Biol. 1997:17:1521-1526.
6. Harris NR, Granger DN. Neutrophil enhancement of reperfusion-induced capillary fluid filtration associated with hypercholesterolemia. Am J Physiol. 1996;271:H1755-H1761.
7. Kurose I, Argenbright LW, Anderson DC, Tolley J, Miyasaka M, Harris N, Granger DN. Reperfusion-induced leukocyte adhesion and vascular protein leakage in normal and hypercholesterolemic rats. Am J Physiol. 1997;273:H854-H860.
8. Granger DN, Korthuis RJ. Physiologic mechanisms of post-ischemic tissue injury. Annu Rev Physiol. 1995;57:311-332.
9. 2 in cultured endothelial cells. Arch Biochem Biophys. 1993;302:348-355.
10. Kurose I, Wolf RE, Grisham MB, Aw TY, Specian RD, Granger DN. Microvascular responses to inhibition of nitric oxide production: role of active oxidants. Circ Res. 1995;76:30-39.
11. Kurose I, Anderson DC, Miyasaka M, Tamatani T, Paulson JC, Todd RF, Rusche JR, Granger DN. Molecular determinants of reperfusion-induced leukocyte adhesion and vascular protein leakage. Circ Res. 1994;74:336-343.
12. Davis MJ. Determination of volumetric flow in capillary tubes using an optical Doppler velocimeter. Microvasc Res. 1987;34:223-230.
13. Emaus RK, Grunwald R, Lemasters JJ. Rhodamine 123 as a probe of transmembrane potential in isolated rat liver mitochondria: spectral and metabolic properties. Biochim Biophys Acta. 1986;850:436-448.
14. Kurose I, Argenbright LW, Wolf R, Liao L, Granger DM. Ischemia-reperfusion-induced microvascular dysfunction: role of oxidants and lipid mediators. Am J Physiol. 1997;272:H2976-H2982.
15. Harrison DG, Ohara Y. Physiologic consequences of increased vascular oxidant stresses in hypercholesterolemia and atherosclerosis: implications for impaired vasomotion. Am J Cardiol. 1995;75:758-818.
16. Alexander RW. Hypertension and the pathogenesis of atherosclerosis: oxidative stress and the mediation of arterial inflammatory response: a new perspective. Hypertension. 1995;25:155-161.
17. Ohara Y, Peterson TE, Sayegh HS, Subramanian RR, Wilcox JN, Harrison DG. Dietary correction of hypercholesterolemia in the rabbit normalizes endothelial superoxide anion production. Circulation. 1995;92:898-903.
18. Cardillo C, Kilcoyne CM, Cannon RO, Quyyumi AA, Panza JA. Xanthine oxidase inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients. Hypertension. 1997;30:57-63.
19. Harrison DG. Cellular and molecular mechanisms of endothelial cell dysfunction. J Clin Invest. 1997;100:2153-2157.
20. Ratych RE, Chuknyska RS, Bulkley GB. The primary localization of free radical generation after anoxia-reoxygenation in isolated endothelial cells. Surgery. 1987;102:122-131.
21. Granger DN. Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol. 1986;90:H80-H85.
22. White CR, Darley-Usmar V, Berrington WR, McAdams M, Gore JZ, Thompson JA, Parks DA, Tarpey MM, Freeman BA. Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits. Proc Nat Acad Sci USA. 1996;93:8745-8749.