Hydrogen atom abstraction of 3,5-disubstituted analogues of paracetamol by horseradish peroxidase and cytochrome P450

Xenobiotica

Volumn 28, Issue 9, 1998, Pages 855-875

  Bessems, J G M ^a,b   De Groot, M J ^a,c   Baede, E J ^a   Te Koppele, J M ^a,b   Vermeulen, N P E ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b TNO   (Netherlands)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CYTOCHROME P450; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; PARACETAMOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CATALYSIS; DRUG METABOLISM; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; LIVER MICROSOME; MALE; NONHUMAN; OXIDATION; RAT;

ACETAMINOPHEN; ANIMALS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; HORSERADISH PEROXIDASE; HYDROGEN; MALE; MICROSOMES, LIVER; NADP; OXIDATION-REDUCTION; RATS; RATS, WISTAR; THERMODYNAMICS;

ANIMALIA; ARMORACIA RUSTICANA; RICKETTSIA SP. PAR;

EID: 0031710907     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982598239100     Document Type: Article

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