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Physiology and pathophysiology of aquaporins
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Molecular physiology of urinary concentrating mechanism: Regulation of aquaporin water channels by vasopressin
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Knepper MA: Molecular physiology of urinary concentrating mechanism: regulation of aquaporin water channels by vasopressin. Am J Physiol 1997, 272:F3-F12. An outstanding summary of both short-term and long-term regulation of AQP2 by vasopressin is given.
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0030860531
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Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea
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Ishibashi K, Kuwahara M, Gu Y, Kageyama Y, Tohsaka A, et al.: Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea. J Biol Chem 1997, 272:20782-20786. The cloning of a new aquaporin (AQP7) from rat testis is reported. AQP7 is expressed abundantly in testis and also facilitates urea and glycerol transport.
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0031589528
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Ishibashi K, Kuwahara M, Kageyama Y, Tohsaka A, Marumo F, Sasaki S. Cloning and functional expression of a second new aquaporin abundantly expressed in testis. Biochem Biophys Res Comm 1997, 237:714-718. The molecular cloning of a new aquaporin (AQP8) from rat testis is reported. It is shown that AQP8 has highest amino acid sequence identity with a plant water channel, suggesting that AQP8 is a unique member in mammalian aquaporins. See also Koyama et al. (J Biol Chem 1997, 272:30329-30333) and Ma et al. (Biochem Biophys Res Comm 1997, 240:324-328).
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8
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0030729487
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Ishibashi K, Kuwahara M, Kageyama Y, Tohsaka A, Marumo F, Sasaki S. Cloning and functional expression of a second new aquaporin abundantly expressed in testis. Biochem Biophys Res Comm 1997, 237:714-718. The molecular cloning of a new aquaporin (AQP8) from rat testis is reported. It is shown that AQP8 has highest amino acid sequence identity with a plant water channel, suggesting that AQP8 is a unique member in mammalian aquaporins. See also Koyama et al. (J Biol Chem 1997, 272:30329-30333) and Ma et al. (Biochem Biophys Res Comm 1997, 240:324-328).
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Koyama1
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9
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0031576555
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Ishibashi K, Kuwahara M, Kageyama Y, Tohsaka A, Marumo F, Sasaki S. Cloning and functional expression of a second new aquaporin abundantly expressed in testis. Biochem Biophys Res Comm 1997, 237:714-718. The molecular cloning of a new aquaporin (AQP8) from rat testis is reported. It is shown that AQP8 has highest amino acid sequence identity with a plant water channel, suggesting that AQP8 is a unique member in mammalian aquaporins. See also Koyama et al. (J Biol Chem 1997, 272:30329-30333) and Ma et al. (Biochem Biophys Res Comm 1997, 240:324-328).
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Biochem Biophys Res Comm
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Ma1
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Molecular cloning of a new aquaporin from rat pancreas and liver
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Koyama Y, Yamamoto T, Kondo D, Funaki H, Yaoita E, Kawasaki K, et al.: Molecular cloning of a new aquaporin from rat pancreas and liver. J Biol Chem 1997, 272:30329-30333. The molecular cloning of a new water channel (AQP8) from rat pancreas and liver is reported. In addition, the expression of AQP8 in hepatocytes, acinal cells of the pancreas and salivary gland, and absorptive colonic epithelial cells is shown. See also Ishibashi et al. (Biochem Biophys Res Comm 1997, 237:714-718) and Ma et al. (Biochem Biophys Res Comm 1997, 240:324-328).
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11
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0031589528
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Koyama Y, Yamamoto T, Kondo D, Funaki H, Yaoita E, Kawasaki K, et al.: Molecular cloning of a new aquaporin from rat pancreas and liver. J Biol Chem 1997, 272:30329-30333. The molecular cloning of a new water channel (AQP8) from rat pancreas and liver is reported. In addition, the expression of AQP8 in hepatocytes, acinal cells of the pancreas and salivary gland, and absorptive colonic epithelial cells is shown. See also Ishibashi et al. (Biochem Biophys Res Comm 1997, 237:714-718) and Ma et al. (Biochem Biophys Res Comm 1997, 240:324-328).
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Biochem Biophys Res Comm
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Ishibashi1
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0031576555
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Koyama Y, Yamamoto T, Kondo D, Funaki H, Yaoita E, Kawasaki K, et al.: Molecular cloning of a new aquaporin from rat pancreas and liver. J Biol Chem 1997, 272:30329-30333. The molecular cloning of a new water channel (AQP8) from rat pancreas and liver is reported. In addition, the expression of AQP8 in hepatocytes, acinal cells of the pancreas and salivary gland, and absorptive colonic epithelial cells is shown. See also Ishibashi et al. (Biochem Biophys Res Comm 1997, 237:714-718) and Ma et al. (Biochem Biophys Res Comm 1997, 240:324-328).
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Biochem Biophys Res Comm
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Ma1
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13
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0031576555
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Cloning of a novel water and urea-permeable aquaporin from mouse expressed strongly in colon, placenta, liver and heart
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Ma T, Yang B, Verkman AS: Cloning of a novel water and urea-permeable aquaporin from mouse expressed strongly in colon, placenta, liver and heart. Biochem Biophys Res Comm 1997, 240:324-328. The cloning of AQP8 from mouse is described. In contrast to the findings in the studies by Ishibashi et al. (Biochem Biophys Res Comm 1997, 237:714-718) and Koyama et al. (J Biol Chem 1997, 272:30329-30333), the authors of this study report that AQP8 is also permeable for urea.
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Biochem Biophys Res Comm
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Ma, T.1
Yang, B.2
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0031589528
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Ma T, Yang B, Verkman AS: Cloning of a novel water and urea-permeable aquaporin from mouse expressed strongly in colon, placenta, liver and heart. Biochem Biophys Res Comm 1997, 240:324-328. The cloning of AQP8 from mouse is described. In contrast to the findings in the studies by Ishibashi et al. (Biochem Biophys Res Comm 1997, 237:714-718) and Koyama et al. (J Biol Chem 1997, 272:30329-30333), the authors of this study report that AQP8 is also permeable for urea.
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Biochem Biophys Res Comm
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Ishibashi1
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15
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0030729487
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Ma T, Yang B, Verkman AS: Cloning of a novel water and urea-permeable aquaporin from mouse expressed strongly in colon, placenta, liver and heart. Biochem Biophys Res Comm 1997, 240:324-328. The cloning of AQP8 from mouse is described. In contrast to the findings in the studies by Ishibashi et al. (Biochem Biophys Res Comm 1997, 237:714-718) and Koyama et al. (J Biol Chem 1997, 272:30329-30333), the authors of this study report that AQP8 is also permeable for urea.
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J Biol Chem
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Koyama1
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16
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Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability
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Kuriyama H, Kawamoto S, Ishida N, Ohno I, Matsuzawa Y, Matsubara K, Okubo K: Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability. Biochem Biophys Res Commun 1997, 241:53-58. The cloning of a novel water channel (AQP9) from adipose tissue is reported. t is shown that AQP9 also facilitates glycerol transport.
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Biochem Biophys Res Commun
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Kuriyama, H.1
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17
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0031214773
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Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chrcmosome locus 12q13
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Ma T, Yang B, Umenishi F, Verkman AS: Closely spaced tandem arrangement of AQP2, AQP5, and AQP6 genes in a 27-kilobase segment at chrcmosome locus 12q13. Genomics 1997, 43:387-389.
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Isolation of human aquaporin 3 gene
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Inase N, Fushimi K, Ishibashi K, Uchida S, Ichioka M, Sasaki S, Marumo F: Isolation of human aquaporin 3 gene. J Biol Chem 1995, 270:17913-17916.
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Jung JS, Preston GM, Smith BL, Guggino WB, Agre P: Molecular structure of the water channel through aquaporin-CHIP. J Biol Chem 1994, 269:14648-14654.
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The three-dimensional structure of aquaporin-1
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Walz T, Hirai T, Murata K, Heymann JB, Mitsuoka K, Fujiy-oshi Y, Smith BL, Agre P, Engel A: The three-dimensional structure of aquaporin-1. Nature 1997, 387:624-627. One of the first studies to show the three-dimensional structure of AQP1 as determined by electron crystallography.
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Cheng A, van Hoek AN, Yeager M, Verkman AS, Mitra AK: Three-dimensional organization of a human water channel. Nature 1997, 387:627-630. One of the first studies to show the three-dimensional structure of AQP1 as determined by electron crystallography.
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Nature
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Cheng, A.1
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Li HL, Lee S, Jap BK: Molecular design of aquaporin-1 water channel as revealed by electron crystallography. Nat Struct Biol 1997, 4:263-265. One of the first studies to show the three-dimensional structure of AQP1 as determined by electron crystallography.
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Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS: Severely impaired urinary concentrating ability of transgenic mice lacking AQP1 water channels. J Biol Chem 1998, 273:4296-4299. The generation of AQP1-knockout mice is reported. It is shown that these mice, in contrast to humans lacking AQP1, have a severe urinary concentrating defect, suggesting that AQP1 is required for the formation of concentrated urine by the kidney.
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Deen PMT, Knoers NVAM: Physiology and pathophysiology of the aqua-porin-2 water channel. Curr Opin Nephrol Hypertens 1998, 7:37-42. This review gives an updated overview of the regulation of collecting duct water permeability by vasopressin and the involvement of AQP2 in diseases with either increased or decreased water reabsorption.
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Vargas-Poussou R, Forestier L, Dautzenberg MD, Niaudet P, Dechaux M, Antignac C: Mutations in the vasopressin V2 receptor and aquaporin-2 genes in 12 families with congenital nephrogenic diabetes insipidus. J Am Soc Nephrol 1997, 8:1855-1862.
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Molecular and cellular defects in nephrogenic diabetes insipidus
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Knoers NVAM, van Os CH: Molecular and cellular defects in nephrogenic diabetes insipidus. Curr Opin Nephrol Hypertens 1996, 5:353-358.
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Curr Opin Nephrol Hypertens
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, pp. 353-358
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Knoers, N.V.A.M.1
Van Os, C.H.2
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41
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0001651763
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Autosomal dominant and autosomal recessive nephrogenic diabetes insipidus: Novel mutations in the AQP2 gene
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Bichet DG, Arthus M-F, Lonergan M, Blfe W, Skorechi K, Nivet H, et al.: Autosomal dominant and autosomal recessive nephrogenic diabetes insipidus: novel mutations in the AQP2 gene. J Am Soc Nephrol 1995, 6:717.
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(1995)
J Am Soc Nephrol
, vol.6
, pp. 717
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Bichet, D.G.1
Arthus, M.-F.2
Lonergan, M.3
Blfe, W.4
Skorechi, K.5
Nivet, H.6
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42
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85038552147
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An AQP2 mutant encoded in dominantly-inherited nephrogenic diabetes insipidus is impaired in its routing from a post-endoplasmic reticulum compartment
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Mulders SMA, Rijss JPL, Kamsteeg E-J, Bichet DG, van Os CH, Deen PMT: An AQP2 mutant encoded in dominantly-inherited nephrogenic diabetes insipidus is impaired in its routing from a post-endoplasmic reticulum compartment [abstract]. J Am Soc Nephrol 1997, 8:23A. This abstract reports for the first time the expression of a mutant AQP2 protein, encoded in a kindred with autosomal dominant nephrogenic diabetes insipidus, in X. leavis oocytes. This mutant is retarded in the Golgi or post-Golgi compartment.
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(1997)
J Am Soc Nephrol
, vol.8
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Mulders, S.M.A.1
Rijss, J.P.L.2
Kamsteeg, E.-J.3
Bichet, D.G.4
Van Os, C.H.5
Deen, P.M.T.6
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43
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0028935612
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Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla
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Marples D, Christensen S, Christensen EI, Ottossen PD, Nielsen S: Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla. J Clin Invest 1995, 95:1838-1845.
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(1995)
J Clin Invest
, vol.95
, pp. 1838-1845
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Marples, D.1
Christensen, S.2
Christensen, E.I.3
Ottossen, P.D.4
Nielsen, S.5
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44
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0029996150
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Hypokalemia-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla and cortex
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Marples D, Frokiaer J, Dorup J, Knepper MA, Nielsen S: Hypokalemia-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla and cortex. J Clin Invest 1996, 97:1960-1968.
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(1996)
J Clin Invest
, vol.97
, pp. 1960-1968
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Marples, D.1
Frokiaer, J.2
Dorup, J.3
Knepper, M.A.4
Nielsen, S.5
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45
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0030820453
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Downregulation of aquaporin-2 parallels changes in renal water excretion in unilateral ureteral obstruction
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Frokiaer J, Christensen BM, Marples D, Djurhuus JC, Jensen UB, Knepper MA, Nielsen S: Downregulation of aquaporin-2 parallels changes in renal water excretion in unilateral ureteral obstruction. Am J Physiol 1997, 273:F213-F223. The development and maintenance of postobstructive polyuria in bilateral ureteral obstruction and release of this blockade are associated with a marked reduction in AQP2 expression in rat collecting ducts.
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(1997)
Am J Physiol
, vol.273
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Frokiaer, J.1
Christensen, B.M.2
Marples, D.3
Djurhuus, J.C.4
Jensen, U.B.5
Knepper, M.A.6
Nielsen, S.7
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46
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0030922702
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Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct
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Nielsen S, Terris J, Andersen D, Ecelbarger C, Frokiaer J, Jonassen T, et al.: Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct. Proc Natl Acad Sci U S A 1997, 94:5450-5455. The authors demonstrate that the increased water retention in rats with congestive heart failure coincides with a marked increase in AQP2 expression and that nearly all AQP2 is located in the apical membrane of collecting duct cells. See also Xu et al. (J Clin Invest 1997, 99:1500-1505).
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(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 5450-5455
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Nielsen, S.1
Terris, J.2
Andersen, D.3
Ecelbarger, C.4
Frokiaer, J.5
Jonassen, T.6
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47
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0030899402
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Nielsen S, Terris J, Andersen D, Ecelbarger C, Frokiaer J, Jonassen T, et al.: Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct. Proc Natl Acad Sci U S A 1997, 94:5450-5455. The authors demonstrate that the increased water retention in rats with congestive heart failure coincides with a marked increase in AQP2 expression and that nearly all AQP2 is located in the apical membrane of collecting duct cells. See also Xu et al. (J Clin Invest 1997, 99:1500-1505).
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(1997)
J Clin Invest
, vol.99
, pp. 1500-1505
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Xu1
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48
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0030899402
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Upregulation of aquaporin-2 water channel expression in chronic heart failure
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Xu DL, Martin PY, Ohara M, St John J, Pattison T, Meng X, et al.: Upregulation of aquaporin-2 water channel expression in chronic heart failure. J Clin Invest 1997, 99:1500-1505. The increased water retention in rats with congestive heart failure coincides with a marked increase in AQP2 expression, and nearly all AQP2 is located in the apical membrane of collecting duct cells. In addition, administration of a vasopressin type 2 receptor antagonist, OPC31260, inhibited this up-regulation completely and resulted in a significant increase in diuresis, a decrease in urinary osmolality, and a rise in plasma osmolality. See also Nielsen et al. (Proc Natl Acad Sci U S A 1997, 94:5450-5455)
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(1997)
J Clin Invest
, vol.99
, pp. 1500-1505
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Xu, D.L.1
Martin, P.Y.2
Ohara, M.3
St John, J.4
Pattison, T.5
Meng, X.6
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49
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0030922702
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Xu DL, Martin PY, Ohara M, St John J, Pattison T, Meng X, et al.: Upregulation of aquaporin-2 water channel expression in chronic heart failure. J Clin Invest 1997, 99:1500-1505. The increased water retention in rats with congestive heart failure coincides with a marked increase in AQP2 expression, and nearly all AQP2 is located in the apical membrane of collecting duct cells. In addition, administration of a vasopressin type 2 receptor antagonist, OPC31260, inhibited this up-regulation completely and resulted in a significant increase in diuresis, a decrease in urinary osmolality, and a rise in plasma osmolality. See also Nielsen et al. (Proc Natl Acad Sci U S A 1997, 94:5450-5455)
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(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 5450-5455
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Nielsen1
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50
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0028814505
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Increased expression of water channel in cirrhotic rat kidneys
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Asahina Y, Izumi N, Enmoto N, Sasaki S, Fushimi K, Marumo F, Sato C: Increased expression of water channel in cirrhotic rat kidneys. Hepatology 1995, 21:169-173.
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(1995)
Hepatology
, vol.21
, pp. 169-173
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Asahina, Y.1
Izumi, N.2
Enmoto, N.3
Sasaki, S.4
Fushimi, K.5
Marumo, F.6
Sato, C.7
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51
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0029561845
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Role of water channel AQP-CD in water retention in SIADH and cirrhotic rats
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Fujita N, Ishikawa S, Sasaki S, Fujisawa G, Fushimi K, Marumo F, Saito T: Role of water channel AQP-CD in water retention in SIADH and cirrhotic rats. Am J Physiol 1995, 38:F926-F931.
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Am J Physiol
, vol.38
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Fujita, N.1
Ishikawa, S.2
Sasaki, S.3
Fujisawa, G.4
Fushimi, K.5
Marumo, F.6
Saito, T.7
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52
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16944367028
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The genetics of primary nocturnal enuresis: Inheritance and suggestion of a second major gene on chromosome 12q
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Amell H, Hjalmas K, Jagervall M, Lackgren G, Stenberg A, Bengttson B, et al.: The genetics of primary nocturnal enuresis: inheritance and suggestion of a second major gene on chromosome 12q. J Med Genet 1997, 34:360-365.
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(1997)
J Med Genet
, vol.34
, pp. 360-365
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Amell, H.1
Hjalmas, K.2
Jagervall, M.3
Lackgren, G.4
Stenberg, A.5
Bengttson, B.6
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53
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0030851768
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Immunolocalization and effect of dehydration on AQP3, a basolateral water channel of kidney collecting ducts
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Ishibashi K, Sasaki S, Fushimi K, Yamamoto T, Kuwahara M, Marumo F: Immunolocalization and effect of dehydration on AQP3, a basolateral water channel of kidney collecting ducts. Am J Physiol 1997, 272:F235-F241.
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(1997)
Am J Physiol
, vol.272
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Ishibashi, K.1
Sasaki, S.2
Fushimi, K.3
Yamamoto, T.4
Kuwahara, M.5
Marumo, F.6
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54
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0030922070
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Water and glycerol permeabilities of aquaporins 1-5 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes
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Yang B, Verkman AS: Water and glycerol permeabilities of aquaporins 1-5 and MIP determined quantitatively by expression of epitope-tagged constructs in Xenopus oocytes. J Biol Chem 1997, 272:16140-16146.
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(1997)
J Biol Chem
, vol.272
, pp. 16140-16146
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Yang, B.1
Verkman, A.S.2
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55
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0030909563
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Very high single channel water permeability of aquaporin-4 in baculovirus-infected insect cells and liposomes reconstituted with purified aquaporin-4
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Yang B, van Hoek AN, Verkman AS: Very high single channel water permeability of aquaporin-4 in baculovirus-infected insect cells and liposomes reconstituted with purified aquaporin-4. Biochemistry 1997, 36:7625-7632.
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(1997)
Biochemistry
, vol.36
, pp. 7625-7632
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Yang, B.1
Van Hoek, A.N.2
Verkman, A.S.3
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56
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0030955183
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Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4
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Ma T, Yang B, Gillespie A, Carlosn EJ, Epstein CJ, Verkman AS: Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. J Clin Invest 1997, 100:957-962. The generation of AQP4-knockout mice is reported. These mice have a mild defect in urinary concentrating ability consistent with the expression of AQP4 in the medullary collecting duct. The AQP4 deletion in these mice has little or no effect on development, survival, growth, and neuromuscular function. In addition, AQP4-knockout mice are free of symptoms related to disturbances in centra osmoregulation.
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(1997)
J Clin Invest
, vol.100
, pp. 957-962
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Ma, T.1
Yang, B.2
Gillespie, A.3
Carlosn, E.J.4
Epstein, C.J.5
Verkman, A.S.6
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57
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0031022918
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Specialized membrane-domains for water transport in glial cells: High resolution immunogold cytochemistry of aquaporin-4 in rat brain
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Nielsen S, Nagelhus EEA, Amiry-Moghaddam M, Bourque C, Agre P, Otterson OP: Specialized membrane-domains for water transport in glial cells: high resolution immunogold cytochemistry of aquaporin-4 in rat brain. J Neurosci 1997, 17:171-180.
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(1997)
J Neurosci
, vol.17
, pp. 171-180
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Nielsen, S.1
Nagelhus, E.E.A.2
Amiry-Moghaddam, M.3
Bourque, C.4
Agre, P.5
Otterson, O.P.6
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58
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0031569812
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Cloning and chromosomal localization of mouse aquaporin 4: Exclusion of a candidate mutant phenotype, ataxia
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Turtzo LC, Lee MD, Lu M, Smoth BL, Copeland NG, Gilbert DJ, et al.: Cloning and chromosomal localization of mouse aquaporin 4: exclusion of a candidate mutant phenotype, ataxia. Genomics 1997, 41:267-270.
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(1997)
Genomics
, vol.41
, pp. 267-270
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Turtzo, L.C.1
Lee, M.D.2
Lu, M.3
Smoth, B.L.4
Copeland, N.G.5
Gilbert, D.J.6
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59
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0030657804
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Aquaporins in complex tissues: II. Subcellular distribution in respiratory and glandular tissues of rat
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Nielsen S, King LS, Christensen BM, Agre P: Aquaporins in complex tissues: II. Subcellular distribution in respiratory and glandular tissues of rat. Am J physiol 1997, 273:C1549-C1561.
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(1997)
Am J Physiol
, vol.273
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Nielsen, S.1
King, L.S.2
Christensen, B.M.3
Agre, P.4
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60
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0030666976
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Aquaporins in complex tissues. Developmenta patterns in respiratory and glandular tissues of rat
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King LS, Nielsen S, Agre P: Aquaporins in complex tissues. Developmenta patterns in respiratory and glandular tissues of rat. Am J Physiol 1997, 273:C1541-C1548
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(1997)
Am J Physiol
, vol.273
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King, L.S.1
Nielsen, S.2
Agre, P.3
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61
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85038539740
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Yasui M, Serlachius E, Lofgren M, Belusa R, Nielsen S, Aperia A: Perinatal changes in expression of aquaporin-4 and other water and ion transporters in rat lung.
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Perinatal Changes in Expression of Aquaporin-4 and Other Water and Ion Transporters in Rat Lung
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Yasui, M.1
Serlachius, E.2
Lofgren, M.3
Belusa, R.4
Nielsen, S.5
Aperia, A.6
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62
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0002522374
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Cloning and expression of two new aquaporins from testis
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Ishibashi K, Kuriyama R, Guy Y, Kuwahara M, Sasaki M, Marumo F: Cloning and expression of two new aquaporins from testis. J Am Soc Nephrol 1997, 8:18A.
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(1997)
J Am Soc Nephrol
, vol.8
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Ishibashi, K.1
Kuriyama, R.2
Guy, Y.3
Kuwahara, M.4
Sasaki, M.5
Marumo, F.6
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