Determination of n-hexane metabolites by liquid chromatography/mass spectrometry 1. 2,5-hexanedione and other phase I metabolites in untreated and hydrolyzed urine samples by atmospheric pressure chemical ionization

Rapid Communications in Mass Spectrometry

Volumn 12, Issue 19, 1998, Pages 1410-1416

  Andreoli, Roberta ^a   Manini, Paola ^a   Mutti, Antonio ^a   Bergamaschi, Enrico ^a   Niessen, Wilfried M A ^b  

^a UNIVERSITY OF PARMA   (Italy)

^b Hyphen MassSpec Consultancy   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ATMOSPHERIC CHEMISTRY; ATMOSPHERIC IONIZATION; ATMOSPHERIC PRESSURE; HEXANE; HYDROLYSIS; LIQUID CHROMATOGRAPHY; METABOLITES; POSITIVE IONS; QUALITY ASSURANCE; QUALITY CONTROL; SPECTROMETRY;

ATMOSPHERIC PRESSURE CHEMICAL IONIZATION; ATMOSPHERIC PRESSURE CHEMICAL IONIZATION LIQUID CHROMATOGRAPHY; HEXANONE; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; N-HEXANE; PHASE CONDITIONS; PHASE I; POSITIVE ION MODE; REVERSED PHASE; URINE SAMPLE;

BIOMOLECULES;

EID: 0031709780     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0231(19981015)12:19<1410::AID-RCM339>3.0.CO;2-M     Document Type: Article

References (22)

1. IPCS, n-Hexane, Environmental Health Criteria 122, WHO, Geneva (1991).
2. G. D. Di Vincenzo, C. J. Kaplan and J. Dedinas, Toxicol. Appl. Pharmacol. 36, 511 (1976).
3. L. Perbellini, F. Brugnone, R. Silvestri and E. Gaffuri, Int. Arch. Occup. Environ. Health 48, 99 (1981).
4. A. Mutti, M. Falzoi, S. Lucertini, G. Arfini, M. Zignani, S. Lombardi and I. Franchini, Br. J. Ind. Med. 4, 533 (1984).
5. T. Kawai, K. Mizunuma, T. Yasugi, Y. Uchida and M. Ikeda, Int. Arch. Occup. Environ. Health 62, 403 (1990).
6. N. Fedtke and H. M. Bolt, Biomed. Environ. Mass Spectrom. 14, 563 (1987).
7. N. Fedtke and H. M. Bolt, Arch. Toxicol. 61, 131 (1987).
8. L. Perbellini, D. Marhuenda Amoros, A. Cardona Llorens, C. Giuliari and F. Brugnone, Br. J. Ind. Med. 47, 421 (1990).
9. T. Soriano, M. Menendez, P. Sanz and M. Repetto, Human Exp. Toxicol. 15, 497 (1996).
10. S. Kezic and A. C. Monster, J. Chromatogr. 563, 199 (1991).
11. J. G. M. van Engelen, S. Kezic, W. de Haan, J. J. G. Opdam and F. A. de Wolff, J. Chromatogr. B 667, 233 (1995).
12. A. A. Nomeir and M. B. Abou-Donia, Anal. Biochem. 151, 381 (1985).
13. I. Marchiseppe, M. Valentino, M. Governa and V. Stocchi, J. Chromatogr. 495, 288 (1989).
14. M. P. Colombini, P. Carrai, R. Fuoco and C. Abete, J. Chromatogr. 592, 255 (1992).
15. M. Ogata, T. Iwamoto and T. Taguchi, Ind. Health 28, 125 (1990).
16. G. Gori, G. B. Bartolucci, A. Sturaro, G. Parvoli, L. Doretti, R. Troiano and B. Casetta, J. Chromatogr. B 673, 165 (1995).
17. L. Maestri, S. Ghittori, M. Imbriani and E. Capodaglio, J. Chromatogr. B 657, 111 (1994).
18. T. Kawai, T. Yasugi, K. Mizunuma, S. Horiguchi, Y. Uchida, O. Iwami, H. Iguchi and M. Ikeda, Int. Arch. Occup. Environ. Health 63, 213 (1991).
19. ACGIH, Threshold Limit Values (TLVs) for Chemical Substances and Physical Agents and Biological Exposures Indices (BEIs) for 1996-1997, ACGIH, Cincinnati, OH (1996).
20. L. Perbellini, G. Pezzoli, F. Brugnone and M. Canesi, Int. Arch. Occup. Environ. Health 65, 49 (1993).
21. A. Mutti, E. Bergamaschi, S. Ghittori, M. Imbriani and I. Franchini, Int. Arch. Occup. Environ. Health 65, S171 (1993).
22. P. Bavazzano, P. Apostoli, C. Balducci, G. B. Bartolucci, M. Buratti, P. Duca, G. Gori, V. Li Donni, L. Perbellini, A. Perico and C. Minoia, Int. Arch. Occup. Environ. Health 71, 284 (1998).