Crotonic acid-directed biosynthesis of the immunosuppressants produced by Streptomyces hygroscopicus var. ascomyceticus

Journal of Fermentation and Bioengineering

Volumn 86, Issue 3, 1998, Pages 261-265

  Sun, Wen Jun ^a   Salmon, Peter ^a   Wilson, James ^a   Connors, Neal ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Biosynthesis; Crotonic acid; Fermentation; Immunomycin; Macrolide; Streptomyces hygroscopicus var. ascomyceticus

Indexed keywords

BIOSYNTHESIS; ENZYMES; FERMENTATION; FERMENTERS; ORGANIC ACIDS;

CROTONIC ACID; IMMUNOMYCIN; MACROLIDE; STREPTOMYCES HYGROSCOPICUS VAR. ASCOMYCETICUS;

ANTIBIOTICS;

ASCOMYCIN; DINOCAP; IMMUNOSUPPRESSIVE AGENT; MACROLIDE;

ANALYTIC METHOD; ARTICLE; BACTERIAL METABOLISM; BIOREACTOR; CARBOXYLATION; ENZYME ACTIVITY; ENZYME SYNTHESIS; EXTRACTION; FERMENTATION; MOLECULAR CLONING; NONHUMAN; STREPTOMYCES HYGROSCOPICUS;

STREPTOMYCES HYGROSCOPICUS;

EID: 0031709044     PISSN: 0922338X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0922-338X(98)80003-2     Document Type: Article

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