Influence of amino acids on the biosynthesis of cyclosporin A by Tolypocladium inflatum

Applied Microbiology and Biotechnology

Volumn 45, Issue 6, 1996, Pages 800-803

  Balakrishnan, K ^a   Pandey, A ^a,b  

^a REGIONAL RESEARCH LABORATORY CSIR   (India)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYCLOSPORIN A; GLYCINE; IMMUNOSUPPRESSIVE AGENT; LEUCINE; METHIONINE; SARCOSINE; VALINE;

ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG SYNTHESIS; FUNGUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; TOLYPOCLADIUM INFLATUM;

EID: 0029785059     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002530050765     Document Type: Article

References (18)

1. Balakrishnan K, Pandey A (1996) Panorama of cyclosporin research. J Basic Microbiol 36:1-27
2. Billich A, Zocher R (1987) Enzymatic synthesis of cyclosporin A. J Biol Chem 262:17 258-17 259
3. Demain AL, Newkirk JF, Hendlin D (1963) Effect of L-methionine in cephalosporin C fermentation. J Bacteriol 85:339-343
4. Gräfe U (1982) In: Krumphanzl V, Sikyta B, Venek Z (eds) Over-production of microbial products. Academic Press, New York, pp 63-75
5. Haavik HI (1981) Biosynthesis of bacitracin role of precursors. FEMS Microbiol Lett 10:111-114
6. Haavik HI, Vessia B (1978) Bacitracin fermentation by Bacillus lichenformis. Acta Path Microbiol Scand [B] 86:67-70.
7. Kleinkauf M, Döhren H von (1983) In: Vining LC (ed) Biochemistry and genetic regulation of commercially important antibiotics. Addison-Wesley, New York, pp 95-145
8. Kobel H, Traber R (1982) Directed biosynthesis of cyclosporins. Eur J Appl Microbiol Biotechnol 14:237-240
9. Kreuzig F (1984) High speed liquid chromatography with convensional instruments for the determination of cyclosporin A, B, C and D in fermentation broth. J. Chromatogr 290:181-186
10. Krumpinski VM, Robbers JE, Floss HG (1976) Role of precursors in ergot alkaloid synthesis. J Bacteriol 125:158-165
11. Lawen A, Zocher R (1990) Non-ribosomal biosynthesis of secondary metabolites. J Biol Chem 268:20 452-20 465.
12. Lawen A, Traber R, Geyl D, Zocher R, Kleinkauf H (1989) Cell free biosynthesis of new cyclosporins. J Antibiot (Tokyo) 42: 1283-1289.
13. Lawen A, Traber R, Reuille R, Ponelle M (1994) In titro biosynthesis of ring extended cyclosporins. Biochem J 300:395-399.
14. Lee J, Agathos SN (1989) Effect of amino acids on the production of cyclosporin A by Tolypocladium inflatum. Biotechnol Lett 11:77-82
15. Matsumura M, Imanaka T, Yoshida T, Taguchi H (1978) Cephalosporin C biosynthesis. J Ferment Technol 56:345-353
16. Pandey A, Balakrishnan K, Nair V (1995) An improved process for the production of cyclosporin A. Indian patent (New Delhi) filed
17. Zocher R, Madry N, Peeters H, Kleinkäuf H (1984) Biosynthesis of cyclosporin A. Phytochemistry 23:549-551.
18. Zocher R, Nihira T, Paul E, Madry N, Peeters H, Kleinkauf H, Keller U (1986) Biosynthesis of cyclosporin A. Biochemistry 25:550-553