Mediation of calcitonin gene-related peptide in protection of ischemic preconditioning in rat hindlimbs

Acta Pharmacologica Sinica

Volumn 19, Issue 5, 1998, Pages 477-480

  Zhou, Fu Wen ^a   Li, Yuan Jian ^a   Deng, Han Wu ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Acetylcholine; Calcitonin gene related peptide; Capsaicin; Norepinephrine; Phenylephrine; Rep erfusion injury; Vasodilation

Indexed keywords

ACETYLCHOLINE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CAPSAICIN; NORADRENALIN; PHENYLEPHRINE;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HINDLIMB; INTRAVENOUS DRUG ADMINISTRATION; LEG ISCHEMIA; MALE; NONHUMAN; RAT; REPERFUSION INJURY; SENSORY NERVE; VASCULAR ENDOTHELIUM; VASOCONSTRICTION; VASODILATATION;

ACETYLCHOLINE; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CAPSAICIN; HINDLIMB; ISCHEMIC PRECONDITIONING; MALE; NOREPINEPHRINE; PHENYLEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; VASOCONSTRICTOR AGENTS; VASODILATION;

EID: 0031695680     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Losano G, Gattullo D, Pagliaro P. Myocardial, neural and vascular aspects of ischemic preconditioning. Life Sci 1996; 59: 1185-92.
2. Parratt JR. Protection of the heart by ischemic preconditioning: mechanisms and possibilities for pharmacological exploitation. Trends Phaimacol Sci 1994; 15: 19-25.
3. Li YJ, Xiao ZS, Peng CF, Deng HW. Calcitonin generelated peptide-induced preconditioning protects against ischemia-reperfusion injury in isolated rat hearts. Eur J Pharmacol 1996; 311: 163-7.
4. Li YJ, Li YJ, Peng CF, Li NS, You JM, Deng HW. Calcitonin gene-related peptide protects against endothelial cell damage due to oxidised low-density lipoprotein. Med Sci Res 1995; 23: 253-4.
5. Loke KE, Woodman OL. Effect of ischemic preconditioning on vascular dysfunction induced by ischemia and reperfusion in rat hindquarters. Cardiovasc Res 1996; 32: 1081-7.
6. Virus RM, McManus DQ, Gebhart GF. Capsaicin treatment in adult Wistar-Kyoto and spontaneously hypertensive rats: neurochemical effects in the spinal cord. Eur J Pharmacol 1983; 92: 1-8.
7. Zhou X, Zhai X, Ashraf M. Preconditioning of bovine endothelial cells: the protective effect is mediated by an adenosine A2 receptor through a protein kinase C signaling pathway. Circ Res 1996; 78: 73-81.
8. Franco-Cereceda A. Calcitonin gene-related peptide and tachyKinins in relation to local sensory control cardiac contractility and coronary vascular tone. Acta Physiol Scand 1988; 133 (Suppl 596): 3-64.
9. Xiao ZS, Li YJ, Deng HW. Ischemic preconditioning mediated by calcitonin gene-related peptide in isolated rat hearts. Acta Pharrnacol Sin 1996; 17: 445-8.
10. Tang YH, Lu R, Li YJ, Deng HW, Liu GZ. Protection by capsaicin against attenuated endotheliumdependent vasorelaxation due to Lysophosphatidylcholine. Naunyn Schmiedebergs Arch Pharmacol 1997; 356: 364-7.
11. Tang YH, Lu R, Li YJ, Peng CF, Deng HW. Effect of calcitonin gene-related peptide-induced preconditioning on attenuated endothelium-dependent vasorelaxation induced by lysophosphatidylcholine. Acta Pharmacol Sin 1997; 18: 405-7.