Insulin-like growth factor-1 (IGF-1) has a costimulatory effect on proliferation of committed progenitors derived from human umbilical cord CD34+ cells

Stem Cells

Volumn 16, Issue 5, 1998, Pages 334-342

  Frostad, S ^a,c   Bjerknes, R ^a   Abrahamsen, J F ^a   Olweus, J ^b   Bruserud, O ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b BD Technologies   (United States)

^c HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

Granulocyte colony stimulating factor; Insulin like growth factor 1 (IGF 1); Umbilical cord hematopoietic stem cells

Indexed keywords

CD15 ANTIGEN; CD34 ANTIGEN; MONOCLONAL ANTIBODY; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 3; RECOMBINANT SOMATOMEDIN C; RECOMBINANT STEM CELL FACTOR;

ANTIGEN EXPRESSION; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; UMBILICAL CORD BLOOD;

EID: 0031695398     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.160334     Document Type: Article

References (29)

1. Beatty PG, Anasetti C, Hansen JA et al. Marrow transplantation from unrelated donors for treatment of hematological malignancies: effect of mismatching for one HLA locus. Blood 1993;81:249-253.
2. Petersdorf EW, Longton GM, Anasetti C et al. The significance of HLA-DRB1 matching on clinical outcome after HLA-A, B, DR identical unrelated donor marrow transplantation. Blood 1995;86:1606-1613.
3. Wagner J. Umbilical cord blood stem cell transplantation. Am J Pediatr Hematol Oncol 1993;15:169-174.
4. Kurtzberg J, Laughlin M, Graham ML et al. Placental blood as a source of hematopoietic stem cells for transplantation into unrelated recipients. N Engl J Med 1996;335:157-166.
5. Kögler G. The effect of different thawing methods, growth factor combinations and media on the ex vivo expansion of umbilical cord blood primitive and committed progenitors. Bone Marrow Transplant 1998;21:233-241.
6. Gmür J, Burger J, Schanz U et al. Safety of stringent prophylactic platelet transfusion policy for patients with acute leukemia. Lancet 1991;338:1223-1226.
7. Barnes R. Infections following bone marrow transplantation. In: Treleaven J, Barret J, eds. Bone Marrow Transplantation in Practice. London, England: Churchill Livingstone, 1992:281-288.
8. + cells is essential for optimal ex vivo expansion of umbilical cord blood cells. J Hematother 1997;6:145-150.
9. Denning-Kendall PA. Is in vitro expansion of human cord blood clinically relevant? Bone Marrow Transplant 1998;21:225-232.
10. Merchav S, Tatarsky I, Hochberg Z. Enhancement of human granulopoiesis in vitro by biosynthetic insulin-like growth factor-1/somatomedin C and human growth hormone. J Clin Invest 1988;81:791-797.
11. Aron DC. Insulin-like growth factor-1 and erythropoiesis. Biofactors 1992;3:211-216.
12. Shimon I, Spielberg O. The insulin-like growth factor system in regulation of normal and malignant hematopoiesis. Leuk Res 1994;19:233-240.
13. Miltenyi S, Müller S, Weichel W et al. High gradient magnetic cell separation with MACS. Cytometry 1990;11:231-238.
14. + cells in peripheral and cord blood by flow cytometry. Exp Hematol 1994;22:1003-1010.
15. + hematopoietic progenitor cells. Blood 1995;85:2402-2413.
16. Olweus J, Terstappen LWMM, Thompson PA et al. Expression and function of receptors for stem cell factor and erythropoietin during lineage commitment of human hematopoietic progenitor cells. Blood 1996;88:1594-1607.
17. + cells from umbilical cord blood, granulocyte colony stimulating factor-mobilized peripheral blood, and adult human bone marrow. J Hematother 1994;3:253-262.
18. hi cells is associated with distinct changes in the expression of the PU.1-regulated molecules, CD64 and macrophage colony-stimulating factor receptor. Blood 1996;88:3741-3754.
19. Geffner M. Effects of growth hormone and insulin-like growth factor I on T- and B-lymphocytes and immune function. Acta Paediatr Suppl 1997;423:76-79.
20. Baserga R. The double life of the IGF-1 receptor. Receptor 1993;2:261-266.
21. Juul A, Bang P, Hertel NT et al. Serum insulin-like growth factor-1 in 1030 healthy children, adolescents, and adults: relation to age, sex, stage of puberty, testicular size, and body mass index. J Clin Endocrinol Metab 1994;78:744-752.
22. Cicognani A, Pession A, Pasini A. IGF-1 and IGFBP-3 concentrations related to stimulated GH following BMT. Bone Marrow Transplant 1998;21:S162.
23. Leroith D. Insulin-like growth factors in health and disease. Ann Intern Med 1992;116:854-862.
24. Juul A, Holm K, Kastrup KW et al. Free insulin-like growth factor I serum levels in 1430 healthy children and adults, and its diagnostic value in patients suspected of growth hormone deficiency. J Clin Endocrinol Metab 1997;82:2497-2502.
25. Laporte J-P, Gorin N-C, Rubinstein P et al. Cord-blood transplantation from an unrelated donor in an adult with chronic myelogenous leukemia. N Engl J Med 1996;335:167-170.
26. Ohmizono Y, Sakabe H, Kimura T et al. Thrombopoietin augments ex vivo expansion of human cord blood-derived hematopoietic progenitors in combination with stem cell factor and flt3 ligand. Leukemia 1997;11:524-530.
27. Donaldson C, Armitage W, Denning-Kendall PA et al. Optimal cryopreservation of human umbilical cord blood. Bone Marrow Transplant 1996;18:725-731.
28. + hemopoietic cells. Leuk Lymphoma 1996;24:11-25.
29. Spence SE, Keller JR, Ruscetti FW et al. Engraftment of ex vivo expanded and cycling human cord blood hematopoietic progenitor cells in SCID mice. Exp Hematol 1998;26:507-514.