Ligation of HLA class I molecules on smooth muscle cells with anti-HLA antibodies induces tyrosine phosphorylation, fibroblast growth factor receptor expression and cell proliferation

International Immunology

Volumn 10, Issue 9, 1998, Pages 1315-1323

  Bian, Hong ^a   Harris, Paul E ^a   Reed, Elaine F ^a  

^a The New York Presbyterian Hospital   (United States)

Author keywords

MHC; Signal transduction; Transplantation

Indexed keywords

CELL PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR; HLA ANTIBODY; HLA ANTIGEN CLASS 1;

ANTIBODY PRODUCTION; ANTIGEN BINDING; ARTICLE; ATHEROSCLEROSIS; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; VASCULAR ENDOTHELIUM;

ANTIBODIES; ARTERIOSCLEROSIS; CELL DIVISION; CELLS, CULTURED; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MUSCLE PROTEINS; MUSCLE, SMOOTH; PHOSPHORYLATION; RECEPTORS, FIBROBLAST GROWTH FACTOR; TRANSPLANTATION; TYROSINE;

EID: 0031692083     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/10.9.1315     Document Type: Article

References (53)

1. Haruhito, A. and Tilney, N. L. 1994. Chronic graft rejection. Curr. Opin. Immunol. 6:770.
2. Paul, L. C. and Fellstrom, B. 1992. Chronic vascular rejection of the heart and kidney - have rational treatment options emerged? Transplantation 53:1169.
3. Hayry, P., Isoniemi, H.,Yilmaz, S., Mennander, A., Lemstrom, K., Raisanen-Sokolowski, A., Koskinen, P., Ustinov, J., Lautenschlager, I., Taskinen, E., Krogerus, L., Aho, P. and Paavonen, T. 1993. Chronic allograft rejection, Immunol. Rev. 134:33.
4. Johnson, D. E., Gao, S. Z., Schroeder, J. S., Decampli, W. M. and Billingham, M. E. 1989. The spectrum of coronary artery pathologic findings in human cardiac allografts. J. Heart Transplant. 8:349.
5. Fenoglio, J., Ho, E., Reed, E., Rose, E., Smith, C., Reemstma, K., Marboe, C. and Suciu-Foca, N. 1989. Anti-HLA antibodies and heart allograft survival. Transplant. Proc. 21:807.
6. Suciu-Foca, N., Reed, E., D'Agati,V. D., Ho, E., Cohen, D. J., Benvenisty, A. I., McCabe, R., Brensilver, J. M., King, D. W. and Hardy, M. A. 1991. Soluble HLA antigens, anti-HLA antibodies and antiidiotypic antibodies in the circulation of renal transplant recipients. Transplantation 51:593.
7. Suciu-Foca, N., Reed, E., Marboe, C. Harris, P., Xi, Y. P., Sun, Y. K., Ho, E., Rose, E., Reemtsma, K. and King, D. W. 1991. The role of anti-HLA antibodies in heart transplantation. Transplantation 51:716.
8. Ende, N., Orsi, E. V., Baturay, N. Z. and Britten, T. L. 1979. Properties of a cytotoxic kidney antibody associated with human renal transplantation. Am. J. Clin. Pathol. 71: 543.
9. Duijvestijn, A. M. and Van Breda Vriesman, P. J. C. 1991. Chronic renal allograft rejection. Selective involvement of the glomerular endothelium in humoral immune reactivity and intravascular coagulation. Transplantation 52:195.
10. Cherry, R., Nielsen, H., Reed, E., Reemtsma, K., Suciu-Foca, N. and Marboe, C. C. 1992. Vascular (humoral) rejection in human cardiac allograft biopsies: relation to circulating anti-HLA antibodies. J. Heart Lung Transplant. 11:24.
11. Reed, E. F., Hong, B., Ho, E., Harris, P. E., Weinberger, J. and Suciu-Foca, N. 1996. Monitoring of soluble HLA alloantigens and anti-HLA antibodies identifies heart allograft recipients at risk of transplant-associated coronary artery disease. Transplantation 61:566.
12. Davenport, A., Younie, M. E., Parsons, J. E. M. and Klouda, P. T. 1994. Development of cytotoxic antibodies following renal allograft transplantation is associated with reduced graft survival due to chronic vascular rejection. Nephrol. Dial. Transplant. 9:1315.
13. Costa, A. N., Scolari, M. P., Iannelli, S., Buscaroli, A., D'Arcangelo, G. L., Brando, B., Indiveri, F., Savi, M., Borgnino, L. C., DeSanctis, L. B., Stefoni, S. and Bonomini, V. 1997. The presence of posttranplant HLA-specific IgG antibodies detected by enzyme-linked immunosorbent assay correlates with specific rejection pathologies. Transplantation 63:167.
14. O'Connell, T. X. and Mowbray, J. F. 1973. Arterial intimal thickening produced by alloantibodies and xenoantibody. Transplantation 51:262.
15. Russell, P. S., Chase, C. M.,Winn, H. J. and Colvin, R. B. 1994. Coronary atherosclerosis in transplanted mouse hearts. II Importance of humoral immunity. J. Immunol. 152:5135.
16. Dasgupta, J. D., Egea, E., Relias, V., Iglesias, A., Gladstone, P. and Yunis, E. J. 1990. Involvement of major histocompatibility complex class I antigens in T cell activation. Eur. J. Immunol. 20:1553.
17. Wacholtz, M. C., Patel, S. S. and Lipsky, P. E. 1989. Patterns of costimulation of T-cell clones: by cross-linking CD3, CD4/ CD8, and class I MHC molecules. J. Immunol. 142: 4201.
18. Geppert, T. D., Wacholtz, M. C., Davis, L. S. and Lipsky, P. E. 1988. Activation of human T4 cells by cross-linking class I MHC molecules. J. Immunol. 140:2155.
19. Roosnek, E., Tunnacliffe, A. and Lanzavecchia, A. 1990. T-cell activation by a bispecific anti-CD3/anti-major histocompatibility complex class I antibody. Eur. J. Immunol. 28:1393.
20. Geppert, T. D., Davis, L. S., Gur, H., Wacholtz, M. C. and Lipsky, P. E. 1990. Accessory cell signals involved in T-cell activation. Immunol. Rev. 117: 5.
21. Geppert, T. D. and Lipsky, P. E. 1988. Activation of T lymphocytes by immobilized monoclonal antibodies to CD3. Regulatory influences of monoclonal antibodies to additional T cell surface determinants. J. Clin. Invest. 81:1497.
22. Hansen, N. Q., Tscherning, T. and Claesson, M. H. 1990 T-cell activation. IV. Evidence for a functional linkage between MHC class I, IL-2 and IL-4 receptor molecules. Cytokine 3:35.
23. Dissing, S., Geisler, C., Rubin, B., Plesner,T. and Claesson, M. H. 1990. T cell activation II. Activation of human T lymphoma cells by cross-linking of their MHC class I antigens. Cell. Immunol. 126:196.
24. Bregenholt, S., Ropke, M., Skov, S. and Claesson, M. H. 1996. Ligation of MHC class I molecules on peripheral blood T lymphocytes induces new phenotypes and functions. J Immunol. 157: 993.
25. Bian, H., Harris, P. E, Mulder, A. and Reed, E. F. 1997. Anti-HLA antibody ligation to HLA class I molecules expressed by endothelial cells stimulates tyrosine phosphorylation, inositol phosphate generation, and proliferation. Human Immunol. 53:90.
26. Reed, E. F., Tugulea, S. L. and Suciu-Foca, N. 1994. Influence of HLA class I and class II antigens on the peripheral T-cell receptor repertoire. Human Immunol. 40:111.
27. Fellstrom, B., Dimeny, E., Larsson, E., Klareskog, L., Tufveson, G. and Rubin, K. 1989. Importance of PDGF receptor expression in accelerated atherosclerosis-chronic rejection. Transplant. Proc. 21:3689.
28. Zhao, X. M., Yeoh, T. K, Frist, W. H., Porterfield, D. L. and Miller, G. G. 1994. Induction of acidic fibroblast growth factor and full-length platelet-derived growth factor expression in human cardiac allografts. Circulation 90:679.
29. Zhao, X. M., Yeoh, T. K., Hiebert, M., Frist, W. H. and Miller. G. G. 1993. The expression of acidic fibroblast growth factor (heparin binding growth factor-1) and cytokine genes in human cardiac allografts and T cells. Transplantation 56:1177.
30. Zhao, X. M., Frist W. H., Yeoh, T. K. and Miller, G. G. 1994. Modification of alternative messenger RNA splicing of fibroblast growth factor receptors in human cardiac allografts during rejection. J. Clin. Invest. 94:992.
31. Kerby, J. D., Verran, D. J., Luo, K. L., Ding, Q., Tagouri, Y., Herrera, G. A., Diethelm, A. G. and Thompson, J. A. 1996. Immunolocalization of FGF-1 and receptors in human renal allograft vasculopathy associated with chronic rejection. Transplantation 62:467.
32. Johnson, D. E. and Williams, L. T. 1993. Structural and functional diversity in the FGF receptor multigene family. Adv. Cancer Res. 60:1.
33. Mohammadi, M., Dikic, I., Sorokin, A., Burgess, W. H., Jaye, M. and Schlessinger, J. 1996. Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction. Mol. Cell Biol. 16:977.
34. Bar-Sagi, D. and Feramisco, J. R. 1985. Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation. Cell 42: 841.
35. Noda, M., Ko, M., Ogura, A., Liu, D. G., Amano, T., Takano, T. and Ikawa, Y. 1985. Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line. Nature 318: 73.
36. Kouhara H., Hadari, Y. R., Spivak-Kroizman, T., Schilling, J., Bar-Sagi, D., Lax, I. and Schlessinger, J. 1997. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89:693.
37. Gay, C. G. and Winkles, J. A. 1990. Heparin-binding growth factor-1 stimulation of human endothelial cells induces plateletderived growth factor A-chain gene expression. J. Biol. Chem. 265:3284.
38. Huang, J., Mohammadi, M., Rodrigues, G. A. and Schlessinger, J. 1995. Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis. J. Biol. Chem. 270:5065.
39. Geppert, T. D., Wacholtz, M. C., Patel, S. S., Lightfoot, E. and Lipsky, P. E. 1989. Activation of human T cell clones and Jurkat cells by cross-linking class I MHC molecules. J. Immunol. 142:3763.
40. Guild, B. C., Erikson, R. L. and Strominger, J. L. 1983. HLA-A2 and HLA-B7 antigens are phosphorylated in vitro by rous sarcoma virus kinase (pp60v) at a tyrosine residue encoded in a highly conserved exon of the intracellular domain. Proc. Natl Acad. Sci. USA. 80:2894.
41. Guild, B. C. and Strominger, J. L. 1984. Human and murine class I MHC antigens share conserved serine 335, the site of HLA phosphorylation in vivo. J. Biol. Chem. 259:9235.
42. Gur, H., El-Zaatari, F., Geppert, T. D., Wacholtz, M. C., Taurog, J. D. and Lipsky, P. E. 1990. Analysis of T cell signaling by class I MHC molecules: the cytoplasmic domain is not required for signal transduction. J. Exp. Med. 172:1267.
43. Due, C., Simonsen, M. and Olsson, L. 1986. The major histocompatibility complex class I heavy chain as a structural subunit of the human cell membrane insulin receptor: implications for the range of biologic functions of histocompatibility antigens. Proc. Natl Acad. Sci. USA 83:6007.
44. Phillips, M. L., Moule, M. L., Delovitch, T. L. and Yip, C. C. 1986. Class I histocompatibility antigens and insulin receptors: evidence for interactions. Proc. Natl Acad. Sci. USA 83:3474.
45. Samson, M., Cousin, J. L. and Fehlmann, M. 1986. Cross-linking of insulin receptors to MHC antigens in human B lymphocytes: evidence for selective molecular interactions. J. Immunol. 137:2293.
46. Schrieber, A. B., Schlessinger, J. and Edidin, M. 1984. Interaction between major histocompatibility complex antigens and epidermal growth factor receptors on human cells. J. Cell. Biol. 98:725.
47. Skov, S., Odum, N. and Claesson, M. H. 1995. MHC class I signaling in T cells leads to tyrosine kinase activity and PLC-γ1 phosphorylation. J. Immunol. 154:1167.
48. Mohammadi, M., McMahon, G., Sun, L., Tang, C., Hirth, P., Yeh, B. K., Hubbard, S. R. and Schlessinger, J. 1997. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science 276:955.
49. Rekhter, M. D. and Gordon, D. 1995. Active proliferation of different cell types, including lymphocytes, in human atherosclerotic plaques. Am. J. Pathol. 147:668.
50. Wick, G., Schett, G., Amberger, A., Kleindienst, R and Xu, Q. 1995. Is atherosclerosis an immunologically mediated disease? Immunol. Today 16:27.
51. Ross, R. 1993. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362:801.
52. King, D. W., Reed, E. and Suciu-Foca, N. 1989. Complexes of soluble HLA antigens and anti-HLA autoantibodies in human sera: possible role in maintenance of self-tolerance. Immunol. Res. 8:249.
53. Beck, S. and Barrell, B. G. 1988. Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens. Nature 331:269.