The role of phosphatidylinositol transfer proteins (PITPs) in intracellular signalling

Trends in Endocrinology and Metabolism

Volumn 9, Issue 8, 1998, Pages 324-328

  Wiedemann, Claudia ^a   Cockcroft, Shamshad ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHATIDYLINOSITOL TRANSFER PROTEIN; PHOSPHOLIPASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ENZYME SUBSTRATE; EXOCYTOSIS; HUMAN; HUMAN CELL; MEMBRANE VESICLE; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; PROTEIN FAMILY; RAT; REVIEW; SIGNAL TRANSDUCTION;

EID: 0031691132     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-2760(98)00080-0     Document Type: Review

References (38)

1. Alb JG, Kearns MA, Bankaitis VA Phospholipid metabolism and membrane dynamics. Curr Biol. 8:1996;534-541.
2. 2+ ion concentrations. Biochem. J 327:1997;545-552.
3. 2+-activated exocytosis. J Biol Chem. 272:1997;19637-19640.
4. Bankaitis VA, Aitken JR, Cleves AE, Dowhan W An essential role for a phospholipid transfer protein in yeast golgi function. Nature. 347:1990;561-562.
5. Brown HA, Gutowski S, Moomaw CR, Slaughter C, Sternweis PC ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity. Cell. 75:1993;1137-1144.
6. Chen YG, Siddhanta A, Austin CDet al. Phospholipase D stimulates release of nascent secretory vesicles from the trans-Golgi network. J Cell Biol. 138:1997;495-504.
7. Cockcroft S, Thomas GMH, Fensome Aet al. Phospholipase D: a downstream effector of ARF in granulocytes. Science. 263:1994;523-526.
8. 2. Curr Biol. 5:1995;775-783.
9. Cunningham E, Tan SW, Swigart P, Hsuan J, Bankaitis V, Cockcroft S The yeast and mammalian isoforms of phosphatidylinositol transfer protein can all restore phospholipase C-mediated inositol lipid signalling in cytosol-depleted RBL-2H3 and HL60 cells. Proc Natl Acad Sci U S A. 93:1996;6589-6593.
10. 2 synthesis. Curr Biol. 6:1996;730-738.
11. Hamilton BA, Smith DJ, Mueller KLet al. The vibrator mutation causes neurogeneration via reduced expression of PITPα: positional complementation cloning and extragenic suppression. Neuron. 18:1997;711-722.
12. Hara S, Swigart P, Jones D, Cockcroft S The first 5 amino acids of the carboxy terminus of phosphatidylinositol transfer protein α (PITPα) play a critical role in inositol lipid signalling: transfer activity of PITP is essential but not sufficient for restoration of phospholipase C signalling. J Biol Chem. 272:1997;14909-14913.
13. 2+-activated secretion. Nature. 366:1993;572-575.
14. 2+-activated secretion. Nature. 374:1995;173-177.
15. Janmey PA Phosphoinositides and calcium as regulators of cellular actin assembly and disassembly. Annu Rev Physiol. 56:1994;169-191.
16. Jenkins GH, Fisette PL, Anderson RA Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid. J Biol Chem. 269:1994;11547-11554.
17. Kauffmann-Zeh A, Thomas GMH, Ball Aet al. Requirement for phosphatidylinositol transfer protein in epidermal growth factor signalling. Science. 268:1995;1188-1190.
18. Kular G, Loubtchenkov M, Swigart Pet al. Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase(γ) in the formylmethionyl-leucylphenylalanine-dependent production of phosphatidylinositol 3,4,5 trisphosphate in human neutrophils. Biochem. J 325:1997;299-301.
19. Lopez MC, Nicaud JM, Skinner HBet al. A phosphatidylinositol/phosphatidylcholine transfer protein is required for the differentiation of the dimorphic yeast Yarrowia lipolytica from the yeast to the mycelial form. J Cell Biol. 124:1994;113-127.
20. Loyet KM, Kowalchyk JA, Chaudhary A, Chen J, Prestwich GD, Martin TFJ Specific binding of phosphatidylinositol 4,5-bisphosphate to calcium-dependent activator protein for secretion (CAPS), a potential phosphoinositide effector protein for regulated exocytosis. J Biol Chem. 273:1998;8337-8343.
21. 2+-activated exocytosis in a cell-free system. J Biol Chem. 272:1997;14447-14453.
22. Milligan SC, Alb JG, Elagina RB, Bankaitis VA, Hyde DR The phosphatidylinositol transfer protein domain of Drosophila retinal degeneration B protein is essential for photoreceptor cell survival and recovery from light stimulation. J Cell Biol. 139:1997;351-363.
23. Morgan CP, Sengelov H, Whatmore J, Borregaard N, Cockcroft S ARF-regulated phospholipase D activity localizes to secretory vesicles and mobilizes to the plasma membrane following MetLeuPhe stimulation of human neutrophils. Biochem. J 325:1997;581-585.
24. Ohashi M, Jan de Vries K, Frank Ret al. A role for phosphatidylinositol transfer protein in secretory vesicle formation. Nature. 377:1995;544-547.
25. Panaretou C, Domin J, Cockcroft S, Waterfield MD Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150-PtdIns 3-kinase complex. J Biol Chem. 272:1997;2477-2485.
26. Paterson HF, Savopoulos JW, Perisic Oet al. Phospholipase C δ1 requires a PH domain for interaction with the plasma membrane. Biochem. J 312:1995;661-666.
27. Rothman JE Mechanisms of intracellular protein transport. Nature. 372:1994;55-63.
28. Schiavo G, Gu QM, Prestwich GD, Sollner TH, Rothman JE Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin. Proc Natl Acad Sci U S A. 93:1996;13327-13332.
29. Shaw G The pleckstrin homology domain: an intriguing multifunctional protein module. BioEssays. 18:1996;35-46.
30. Stack JH, Herman PK, Schu PV, Emr SD A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole. EMBO. J 12:1993;2195-2204.
31. 2 concentration monitored in living cells. Curr Biol. 8:1998;343-346.
32. Thomas GMH, Cunningham E, Fensome Aet al. An essential role for phosphatidylinositol transfer protein in phospholipase C-mediated inositol lipid signalling. Cell. 74:1993;919-928.
33. Tuscher O, Lorra C, Bouma B, Wirtz KWA, Huttner WB Cooperativity of phosphatidylinositol transfer protein and phospholipase D in secretory vesicle formation from the TGN - phosphoinositides as a common denominator. FEBS Lett. 419:1997;271-275.
34. Wang D, Miller R, Shaw R, Shaw G The pleckstrin homology domain of human β1 II spectrin is targeted to the plasma membrane in vivo. Biochem Biophys Res Commun. 225:1996;420-426.
35. Whatmore J, Morgan CP, Cunningham E, Collison KS, Willison KR, Cockcroft S ADP-ribosylation factor1-regulated phospholipase D is localized at the plasma membrane and intracellular organelles in HL60 cells. Biochem. J 320:1996;785-794.
36. Wiedemann C, Schafer T, Burger MM Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion. EMBO. J 15:1996;2094-2101.
37. Willars GB, Nahorski SR, Challiss RAJ Differential regulation of muscarinic acteylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells. J Biol Chem. 273:1998;5037-5046.
38. Wirtz KWA Phospholipid transfer proteins. Annu Rev Biochem. 60:1991;73-99.